Clinical trials: Pulmonary Embolism (PE)
Deep Vein Thrombosis, Pulmonary Embolism
3 Months' Versus 6 Months' Anticoagulation in Patients With DVT and/or PE
To determine whether 3 months' anticoagulation is as good as or better than 6 months' for the treatment of DVT/PE
- Conditions
- Deep Vein Thrombosis, Pulmonary Embolism, Deep Vein Thrombosis With Pulmonary Embolism
- Trial name
- NCT00365950
- Testing
- Duration of anticoagulation, Warfarin duration
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,400 people
- Sponsor
- British Thoracic Society
PE - Pulmonary Embolism, PE - Pulmonary Thromboembolism
FlowTriever for Acute Massive Pulmonary Embolism (FLAME)
To evaluate treatment outcomes of patients diagnosed with high-risk (massive) pulmonary embolism
- Trial name
- FLAME (NCT04795167)
- Where
- 11 sites in United States
- Volunteers
- 115 people
- Sponsor
- Inari Medical
Pulmonary Embolism
The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
To demonstrate the efficacy and safety of the 8F BASHIR™ .035 Endovascular Catheter and the 8F BASHIR™ S-B .035 Endovascular Catheter for the administration of pharmaco-mechanical catheter directed therapy using pulse sprays of…
- Trial name
- NCT06433011
- Testing
- The Bashir™ Endovascular Catheter, r-tPA
- Where
- 23 sites in United States
- Volunteers
- 500 people
- Sponsor
- Thrombolex, Inc.
Cancer, Venous Thromboembolism
Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer
The overarching objective of the study is to determine the effectiveness of LMWH/ warfarin vs. DOAC anticoagulation for preventing recurrent VTE in cancer patients.
- Conditions
- Cancer, Venous Thromboembolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE)
- Trial name
- CANVAS (NCT02744092)
- Testing
- Rivaroxaban, Apixaban, Edoxaban
- Where
- 151 sites in United States
- Volunteers
- 811 people
- Sponsor
- Alliance Foundation Trials, LLC.
Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension
Chinese PE Multimodality Imaging Artificial Intelligence Study
The CHinese pulmOnary Embolism Multimodality Imaging-artifiCial intelligencE Study (CHOICE) is a prospective observational multi-center study that will collect imaging text data and raw data of patients with pulmonary embolism…
- Conditions
- Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Disease
- Trial name
- NCT06526468
- Testing
- Artificial Intelligence
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Pulmonary Embolism, Deep Vein Thrombosis
Angel® Catheter Early Feasibility Clinical Study
The primary objective of this clinical trial is to obtain initial insights into the safety of the Angel® Catheter in critically ill subjects with high risk of venous thromboembolism (VTE) disease AND who are not receiving…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Venous Thromboembolism
- Trial name
- NCT01847196
- Testing
- Angel® Catheter
- Where
- 4 sites in United States
- Volunteers
- 6 people
- Sponsor
- BiO2 Medical
Acute Pulmonary Embolism (PE)
Surgical Pulmonary Embolectomy Versus Catheter-directed Thrombolysis in the Treatment of Pulmonary Embolism: A Non-inferiority Study
Acute pulmonary embolism (PE) is a serious and potentially lethal condition. The clinical spectrum of PE spans from asymptomatic PE to patients with severe hemodynamic compromise.
- Trial name
- Lungembolism (NCT03218410)
- Testing
- surgical pulmonary embolectomy, catheter-directed thrombolysis
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pulmonary Embolism
Assessing the Prognosis of Pulmonary Embolism Using Clinical and Imaging Biomarkers (Retrospective & Prospective )
Venous thromboembolism (VTE), which clinically manifests as deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common but elusive illness that can cause significant disability and death if not promptly diagnosed and…
- Trial name
- NCT00805246
- Where
- 2 sites in United States
- Volunteers
- 910 people
- Sponsor
- University of Pittsburgh
Pulmonary Embolism, Atrial Fibrillation
Evaluation of the Accuracy and Precision of the INRatio® Prothrombin Time (PT) Monitoring System With New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity
This is a multi-center study designed to evaluate the accuracy and precision of the INRatio® Prothrombin Time (PT) Monitoring System, utilizing the INRatio test strip newly designed for low sample volume and heparin…
- Conditions
- Pulmonary Embolism, Atrial Fibrillation, Deep Vein Thrombosis
- Trial name
- ECLIPSE-01 (NCT01037270)
- Where
- 4 sites in United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Abbott RDx Cardiometabolic
Pulmonary Embolism
DS-9231 in Intermediate-risk (Sub-massive) Acute Pulmonary Embolism (PE)
The primary objective of this study is to evaluate safety and initial effectiveness of DS-9231 when taken together with current standard of care.
- Trial name
- NCT03316729
- Testing
- DS-9231
- Sponsor
- Daiichi Sankyo
PE - Pulmonary Embolism, PE - Pulmonary Thromboembolism
Stent-Retriever for Acute Massive Pulmonary Embolism (SRAME)
To evaluate treatment outcomes of patients diagnosed with pulmonary embolism.
- Trial name
- SRAME (NCT05992168)
- Testing
- Stent-Retriever
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Suzhou Zenith Vascular SciTech Limited
Venous Thromboembolic Disease, Deep Venous Thrombosis
Registry of Angiovac Procedures In Detail Outcomes Database-RAPID Registry
Venous thromboembolic disease is a significant cause of morbidity and mortality. The purpose of the RAPID registry is to collect information on the Angiovac procedure and Angiovac device used in the treatment of deep venous…
- Conditions
- Venous Thromboembolic Disease, Deep Venous Thrombosis, Right Heart Pathology, Pulmonary Embolism
- Trial name
- RAPID (NCT04414332)
- Testing
- Data collection only
- Volunteers
- 234 people
- Sponsor
- University of California, Los Angeles
Dyspnea, Pulmonary Embolism
Inhaled Nitric Oxide (iNO) in Post-Pulmonary Embolism (Post-PE)
Following acute pulmonary embolism (PE), up to a third of patients develop post-PE syndrome described as having persistent breathlessness (dyspnea), impaired exercise capacity, and a reduced quality of life.
- Trial name
- NCT04920695
- Testing
- Nitric Oxide
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Dr. Denis O'Donnell
Acute Pulmonary Embolism (PE)
Prognostic Factors for Acute Pulmonary Embolism in Critically Ill Patients
Acute pulmonary embolism (PE) is an important cause of in-hospital mortality and may be rapidly fatal if not diagnosed and treated.
- Trial name
- NCT01839266
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Pulmonary Embolism, Pulmonary Embolus/Emboli
Non-Invasive Measurement of Cardiac Output and Stroke Volume in PE
Pulmonary embolism impacts over 1 in 1000 adults annually and is the third leading cause of cardiovascular death after heart attack and stroke. The consequence of each PE is widely variable.
- Conditions
- Pulmonary Embolism, Pulmonary Embolus/Emboli, Pulmonary Disease, Pulmonary Embolism and Thrombosis
- Trial name
- NCT04855370
- Testing
- Non-invasive hemodynamic measurements
- Where
- United States
- Sponsor
- University of California, Los Angeles
Acute Pulmonary Embolism
A Phase II Study to Evaluate the Efficacy of ThromboView® in the Detection of Pulmonary Emboli
The aim of the study is to determine the diagnostic accuracy of 99mTc ThromboView® SPECT imaging for the detection of acute pulmonary embolism (PE) in patients for whom there is a moderate to high clinical suspicion for PE.
- Trial name
- NCT00519506
- Testing
- ThromboView
- Where
- 6 sites in United States, Canada
- Volunteers
- 61 people
- Sponsor
- Agen Biomedical
Thrombosis, Deep Venous Thrombosis
Venous Thromboembolism and Haemostatic Disturbances in Patients With Upper Gastrointestinal Cancer
Cancer is a well known risk factor for venous thromboembolism (VTE) such as deep venous thrombosis (DVT) and pulmonary embolism (PE).
- Conditions
- Thrombosis, Deep Venous Thrombosis, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- GIVTE (NCT00660205)
- Where
- Denmark
- Volunteers
- 285 people
- Sponsor
- University of Aarhus
Acute DVT of Lower Extremity
Vascular Boot Warming Program After Acute Deep Vein Thrombosis (DVT) ± Pulmonary Embolism (PE)
The Researchers are studying whether a vascular boot warming program plus standard of care anticoagulation can be a safe and effective method to resolve Deep Vein Thrombosis (DVT) ±Pulmonary Embolism (PE) earlier and prevent…
- Trial name
- NCT03465735
- Testing
- Vascular Boot, Standard of Care
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Venous Thromboembolism, Thoracic Surgery
Incidence of Venous Thromboembolism in Patients Undergoing Major Esophageal Resection
The purpose of this study is to determine the incidence of post-operative venous thromboembolism (VTE) in patients undergoing major esophageal resection for malignancy.
- Conditions
- Venous Thromboembolism, Thoracic Surgery, Esophageal Cancer
- Trial name
- NCT03115541
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 187 people
- Sponsor
- McMaster University
Pulmonary Embolism Acute, Pulmonary Embolism Acute Massive
Cohort Study on Treatment Comes of Catheter-based Therapy in Patients With Acute Pulmonary Embolism in Hong Kong
This retrospective cohort study (Hong Kong PECT Registry) compares treatment outcomes between different percutaneous catheter-based therapies in patients with acute pulmonary embolism (PE).
- Conditions
- Pulmonary Embolism Acute, Pulmonary Embolism Acute Massive, Pulmonary Embolism Subacute Massive
- Trial name
- HK-PECT (NCT07029841)
- Testing
- catheter-based therapy
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong