Clinical trials: Pulmonary Function Tests, open to volunteers
Asthma
Nutrition for Asthmatics
Determine to what extent three distinct dietary approaches improve asthma control and lung function.
- Trial name
- INHALE (NCT06151405)
- Testing
- DGA Diet, MCT Diet, KETO Diet
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pennington Biomedical Research Center
Thoracic Neoplasms
The Effects of a Family-Centered Tai Chi Exercise on Lung Function and Mental Health of Patients After Thoracoscopic Surgery
To explore the effect of a family-centered, eight-week, progressive sit-to-stand Tai Chi exercise on lung function and mental health in patients after thoracoscopic surgery_
- Trial name
- NCT06104774
- Testing
- Tai Chi Exercise
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Lung Cancer, Pneumonitis
Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy
The goal of this clinical trial is to learn if using an incentive spirometer can reduce lung problems in people with advanced lung cancer who are receiving chemotherapy and radiation therapy.
- Conditions
- Lung Cancer, Pneumonitis, Radiation-Induced Lung Injury, Immunotherapy-Induced Pneumonitis
- Trial name
- INSPIRE-CRT (NCT06688422)
- Testing
- incentive spirometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cooper Norcross Health
Respiratory Muscles, Cardiorespiratory Fitness
Effects of Aerobic and Diaphragmatic Exercises on Choir Singers
The goal of this randomized-controlled study is to compare the effects of diaphragmatic breathing exercise training provided by a physiotherapist and aerobic exercise training applied in addition to diaphragmatic breathing…
- Trial name
- NCT06745869
- Testing
- Diaphragmatic breathing exercise training, Aerobic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medipol University
Asthma
Alternate Nostril Breathing With Incentive Spirometry on Lung Function Among Asthma Patients
To compare effects of Alternate Nostril Breathing exercise with incentive spirometer on lung functions (forced vital capacity, forced expiratory volume, and peak expiratory flow rate) in Asthma patients.
- Trial name
- NCT07110116
- Testing
- Alternate nostril breathing with Incentive Spirometery, Incentive spirometery
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease (COPD)
Intermittent Hypoxemia, Lung Function Decline, Morbidity, and Mortality in COPD (PROSA Study).
This study aims to analyze if patients with chronic obstructive lung disease who experience a decline of blood oxygen saturation during physical exercise have a disease course different from that of COPD patients who do not…
- Trial name
- PROSA (NCT06265623)
- Testing
- No active intervention, but observational follow-up
- Where
- Germany
- Volunteers
- 148 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hypoxemia of Newborn
Lung Function Monitoring During Hypoxemia Episodes
Premature infants commonly have desaturation episodes due to different reasons such as cessation of breathing or loss of lung volume.
- Trial name
- NCT06535074
- Testing
- Detecting changes in lung volume with hypoxemia episodes
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Rutgers, The State University of New Jersey
AIDS, Pneumonia
Risk Identification Factors for Pulmonary Function Impairment in AIDS Patients Recovered From Severe Pneumonia
Screening for risk factors related to lung function impairment in patients who have recovered from AIDS with severe pneumonia, to provide clinical evidence for early identification and intervention of lung function damage in this…
- Trial name
- NCT06137196
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou 8th People's Hospital
Asthma, COPD
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.
- Conditions
- Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis
- Trial name
- NCT04624490
- Testing
- Hyperpolarized Xe129
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Mario Castro, MD, MPH
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Lung Function and Respiratory Muscle Strength Following Training of the Inspiratory Muscles in Frail Older Adults (IMT-3)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on lung function and respiratory muscle strength in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07556445
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Vagus Nerve Stimulations, Spirometry
Transcutaneous Auricular Vagus Nerve Stimulation and Spirometry: Sham-Controlled Randomized Trial
This study will examine the short-term effects of transcutaneous auricular vagus nerve stimulation (a non-invasive electrical stimulation delivered through the outer ear) on lung function measured by spirometry in healthy adults.
- Conditions
- Vagus Nerve Stimulations, Spirometry, Autonomic Nervous System (ANS) Functioning and Mood State, Blood Pressure Monitoring
- Trial name
- taVNS-SPIRO (NCT07482930)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide
Test-Retest Reliability And Validation For End-Tidal Carbon Dioxide Measurement (PetCO2) During Rest And Low-Loaded Steady State Work Using A Portable Capnograph.
The goal of this observational study is to investigate exhaled carbon dioxide measuring during rest and low-loaded work using a portable device (capnograph) and standard of care apparatus during a cardiopulmonary exercise test…
- Conditions
- Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide, VO2max, Ventilatory Physiology
- Trial name
- NCT07326449
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Linkoeping University
Primary Ciliary Dyskinesia (PCD)
Malnutrition and Sarcopenia Among Primary Ciliary Dyskinesia
The prevalence and causes of malnutrition and sarcopenia in children and adolescents with Primary ciliary dyskinesia (PCD) have not been sufficiently elucidated.
- Trial name
- Malnutrition (NCT07740538)
- Testing
- Physical assessments of individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Izmir Democracy University
COPD, Obesity & Overweight
GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD
Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation, obesity-related metabolic dysfunction, skeletal muscle impairment, and progressive decline in lung function.
- Conditions
- COPD, Obesity & Overweight, Sarcopenia
- Trial name
- GLIMR COPD (NCT07747805)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
COPD, Chronic Obstructive Pulmonary Disease (COPD)
Phase 2b Efficacy and Safety Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD Patients
This is a phase 2b, randomized, double-blind, placebo-controlled, dose-ranging,14-day dosing, 2-period crossover study in participants with chronic obstructive pulmonary disease (COPD).
- Conditions
- COPD, Chronic Obstructive Pulmonary Disease (COPD), Lung Disease Chronic, Lung Diseases, Obstructive
- Trial name
- AERODUO-2 (NCT07896252)
- Testing
- AERO-001, AERO-002, AERO-007
- Where
- 2 sites in United Kingdom
- Volunteers
- 64 people
- Sponsor
- AeroRx Therapeutics Inc.
Breathing, Lung Function Decreased
Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry
This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on methacholine challenge testing and whether these findings are associated with body habitus,
- Conditions
- Breathing, Lung Function Decreased, Asthma (Diagnosis), Obesity
- Trial name
- BREATH-OSC (NCT07356310)
- Testing
- Oscillometer
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
COPD, COPD Exacerbation Acute
The Italian Registry of Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a treatable but debilitating medical condition associated with persistent symptoms and chronic airflow obstruction.
- Conditions
- COPD, COPD Exacerbation Acute, Comorbid Chronic Lung Disease on Heart Failure, Mortality
- Trial name
- ICoRe (NCT06652776)
- Testing
- Pharmacological treatment
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- University of Milan
Respiratory Function Tests，Heart Function Tests, Cardiopulmonary Function
Xiangya Cardiopulmonary Health and Disease Cohort
Xiangya Cardiopulmonary Health and Disease Cohort (XY-CPHDC) is a non-intervention study grounded in real-world data. It is designed as a bidrectional clinical cohort combined retrospective and prospective design, in order to…
- Trial name
- XY-CPHDC (NCT06972784)
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Asthma
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction.
- Trial name
- NCT01225913
- Testing
- fluticasone/salmeterol in all asthmatics, budesonide/formoterol or fluticasone/salmeterol in all asthmatics
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gelb, Arthur F., M.D.
NSCLC Diagnosed by Histology or Cytology, A Multidisciplinary Team Assessment Determined That the Patient Was a Suitable Candidate for Radical Surgical Resection
Phase II Clinical Study of Probiotic LR607 in Patients With Non-Small Cell Lung Cancer
The goal of this clinical trial is to understand whether Lactobacillus rhamnosus LR607 can enhance neoadjuvant chemoimmunotherapy for adult patients with non-small cell lung cancer. It will also evaluate the safety of LR607.
- Conditions
- NSCLC Diagnosed by Histology or Cytology, A Multidisciplinary Team Assessment Determined That the Patient Was a Suitable Candidate for Radical Surgical Resection, Overall Lung Function is Adequate for the Planned Lung Resection, AJCC is Classified as IIA-IIIB
- Trial name
- NCT07534033
- Testing
- Probiotics combined with neoadjuvant chemoimmunotherapy
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Zhujiang Hospital