Clinical trials: Pulmonary Insufficiency
Pain
Use of Intrathecal Hydromorphone in Elective Cesarean Deliveries
The purpose of this study is to determine if intrathecal hydromorphone will relieve pain as well as intrathecal morphine after cesarean delivery, with fewer side effects.
- Trial name
- NCT01866254
- Testing
- Hydromorphone, Morphine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Grace Shih, MD
Airway Obstruction, Hypertension
Epidemiological Study on the Relationship Between Respiratory Health and Air Pollution From Industrial Sources
The ELISABET STUDY is across sectional Survey on a representative sample of two urban area conduct on a representative sample. The main objective of the project is to compare the prevalence of the obstructive ventilatory…
- Conditions
- Airway Obstruction, Hypertension, Diabetes Mellitus, Dyslipidemias
- Trial name
- ELISABET (NCT02490553)
- Testing
- heteroevaluation scale by a nurse or doctor
- Volunteers
- 3,276 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cystic Fibrosis, Pancreatic Insufficiency
Beta-cell Response to Incretin Hormones in Cystic Fibrosis
In recent years, diabetes has emerged as one of the most significant co-diseases that many Cystic Fibrosis (CF) patients develop.
- Trial name
- NCT01851694
- Testing
- GLP-1, GIP
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Nasal Obstruction
The Vivaer Procedure for Treatment of the Septal Swell Bodies (SWELL)
Post-market study to access the clinical use of the Vivaer Arc Stylus to treat Septal Swell Bodies (SSB).
- Trial name
- SWELL (NCT05099263)
- Testing
- Vivaer Arc Stylus
- Where
- 9 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aerin Medical
Respiratory Depression, Blood Pressure
Cardiopulmonary Responses to Exposure to Ozone and Diesel Exhaust
The US EPA Clean Air Multiyear research program is moving toward a multi-pollutant approach to the assessment of air pollution in response to recommendations by the NRC 2004 and the BOSC in 2005.
- Trial name
- DEPOZ (NCT01874834)
- Testing
- ozone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Respiratory Depression, Cannabis Use
Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers
Rationale: Opioid misuse and abuse are common problems in the Western world. The rate of unintentional drug overdose is rapidly increasing, not only in the Unites States but also in the Netherlands.
- Conditions
- Respiratory Depression, Cannabis Use, Opioid Use
- Trial name
- COXY (NCT05235503)
- Testing
- Medicinal cannabis in combination with oxycodon
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Respiratory Failure, Acute Dyspnoea
A New Way of Looking at Your Lungs
There is increasing interest in how thoracic (chest) ultrasound might enhance the management of patients with respiratory failure and breathlessness, particularly in the emergency admissions or intensive care setting.
- Trial name
- NCT01949402
- Testing
- Computed Tomography, Thoracic ultrasound, Spirometry
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hypercapnia, Ventilatory Depression
Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on Ventilation
This study is designed to evaluate the effects of the coadministration of paroxetine or escitalopram with an opioid on ventilation. Ventilation will be assessed using a rebreathing methodology.
- Trial name
- NCT05470465
- Testing
- Paroxetine and Oxycodone, Escitalopram and Oxycodone
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Food and Drug Administration (FDA)
Respiratory Depression
TAES Improve the Function of Respiration and Circulation on Elderly Patients Undergoing Colonoscopy Procedure
To explore the effectiveness of transcutaneous acupuncture electrical stimulation (TAES), a non-invasive modality in improvement of the function of respiration and circulation on elder patient during colonoscopy.
- Trial name
- NCT03775122
- Testing
- TAES
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Lung Neoplasms Accompanied by Respiratory Function Insufficiency
Irreversible Electroporation(IRE) For Lung Neoplasms Accompanied by Respiratory Function Insufficiency
The purpose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for Lung Neoplasms accompanied by Respiratory Function Insufficiency.
- Trial name
- IRE (NCT02430753)
- Testing
- Irreversible electroporation (IRE), NanoKnife
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Slow Breathing, Acute Myocardial Infarction
The Effect of Slow Breathing Exercise Applied to Patients on Pulse, Blood Pressure and Quality of Life
This study was designed as a randomized controlled experimental type in order to determine the effect of slow breathing exercise applied after the procedure on heart rate, blood pressure and quality of life in patients who…
- Trial name
- NCT06098222
- Testing
- Slow breathing exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Trauma, Rib Fractures
Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures
The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes.
- Conditions
- Trauma, Rib Fractures, Chest Wall Disorder, Respiratory Insufficiency
- Trial name
- NCT06533904
- Testing
- Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
COVID-19
A Study to Learn How Renal Impairment Affects the Pharmacokinetics of PF-07817883.
The purpose of the study is to learn about: how PF-07817883 is processed in the body of adult participants. the safety of PF-07817883.
- Trial name
- NCT06586216
- Testing
- PF-07817883
- Where
- 3 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Dementia, Diabetes Mellitus
Impact of Lifestyle Modification on the Development of Dementia, Chronic Kidney Disease, Diabetes, Chronic Obstructive Pulmonary Disease, Cancers and Cardiovascular Disease in a Thai General Population
This is a community-based cluster randomized control trial aimed to investigate the impact of lifestyle modification (diet, physical activity, alcohol drinking and smoking) on the development of dementia, diabetes, chronic kidney…
- Conditions
- Dementia, Diabetes Mellitus, Chronic Kidney Disease, Cardiovascular Diseases
- Trial name
- NCT02967406
- Testing
- 4 x 4 lifestyle modification
- Where
- Thailand
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Choking, Airway Obstruction
Evaluation of Foreign Body Airway Obstruction Interventions Through Simulation
WHY IS THIS STUDY BEING DONE? Little is known about the best treatment for choking. New airway clearance devices like LifeVac© and Dechoker© are being sold to help a choking person.
- Trial name
- NCT06227234
- Testing
- Dechoker, LifeVac, Abdominal Thrusts
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cardiovascular Diseases, COPD
The Cartagena Cohort Study
Cardiovascular and respiratory diseases are the first and third cause of death, respectively. Cardiovascular risk is known to increase in groups with impaired lung function; however, the mechanisms behind this association are not…
- Conditions
- Cardiovascular Diseases, COPD, Lung Function Decreased, Atherosclerosis
- Trial name
- CaReS (NCT05339048)
- Testing
- Genetic risk variants, Diet, Physical activity
- Where
- Colombia
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- Universidad de Cartagena