Clinical trials: Pulmonary Nodules
Pulmonary Nodules, Multiple
Detection and Volumetry of Pulmonary Nodules on Ultra-low Dose Chest CT Scan With Deeplearning Image Reconstruction Algorithm (DLIR)
evaluate the diagnostic performance of ultra-low dose CT using deep learning-based reconstruction in the detection of pulmonary nodules.
- Trial name
- DLIRTHORAX (NCT04482114)
- Testing
- ULD CT
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pulmonary Nodule, Solitary
The MDA Test to Differentiate of Benign and Malignant Pulmonary Nodules
The purpose of the study is the identification of the efficacy of MDA Test to Differentiate of Benign and Malignant Pulmonary Nodules.
- Trial name
- NCT03790735
- Testing
- FISH
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Lung Cancer (Diagnosis)
Prospective Multicenter Cohort Study for the Development and Evaluation of Risk Stratification Tools for Lung Cancers and Their Postoperative Recurrences Using Multimodal Clinical, Radiological, Tissue and Longitudinal Biological Phenotyping Among People at Risk of Lung Cancer
Interventional study with minimal risks and constraints, involving annual assessment of the prevalence and incidence of lung cancer using low-dose contrast-free thoracic CT scans, immunological, inflammatory, metabolic, blood…
- Trial name
- LUCA-pi COHORT (NCT07042867)
- Testing
- biobanking, low dose scan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Lung Cancer, Metastatic Cancer in the Lungs
Early Detection of Lung Cancer Via Bi-plane Correlation Chest Imaging
This project proposes a new method, Bi-plane Correlation Imaging (BCI), for improved detection of subtle lung nodules. In BCI, two digital radiographs of the chest are acquired within a short time interval from slightly different…
- Trial name
- NCT00673283
- Testing
- bi-plane chest radiography
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Duke University
Lung Cancer
Early Cancer Detection Test - Lung Cancer China
Lung cancer is the most common cancer in China from both incidence and mortality rate point of view, with significantly lower 5-year survival rate than average. Early detection is the recognized solution.
- Trial name
- ECLC (NCT04216511)
- Testing
- Tumor autoantibody detection
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Bai Chunxue
Pain, Pulmonary Nodules
Effect of CYP2D6*10 Gene Mutation on Perioperative Precision Analgesia of Oxycodone in Elderly Patients
The purpose of this prospective study was to determine the effect of CYP2D6 gene polymorphism on perioperative analgesia of oxycodone in elderly patients, and to assign the CYP2D6 phenotype according to the genotype, and to use…
- Conditions
- Pain, Pulmonary Nodules, Oxycodone
- Trial name
- NCT07484867
- Testing
- oxycodone
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Lung Cancer Screening, Asbestos
Artificial Intelligence in Lung Cancer Screening
Single-center, non-profit, observational, retrospective study of collection of clinical and amnestic data and images to create, implement and develop a pilot model of an integrated virtual platform.
- Trial name
- INAIL BRIC (NCT06444373)
- Where
- Italy
- Volunteers
- 728 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Lung Neoplasms, Computed Tomography
Methods of Computed Tomography Screening and Management of Lung Cancer
European lung cancer screening studies using computed tomography (CT) have shown that a management protocol based on measuring lung nodule volume and volume doubling time (VDT) is more specific for early lung cancer detection…
- Conditions
- Lung Neoplasms, Computed Tomography, Mass Screening, Lung Nodules
- Trial name
- NCT03992833
- Testing
- lung cancer screening
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
COVID 19, Inflammatory Status
FOUND - Ancillary Study to Smile Protocol NCT03654105
During the current pandemic, in Italy the majority of asymptomatic or pauci-symptomatic COVID-19 cases were not identified nor diagnosed and this fact caused a decrease in the effectiveness of the various containment measures…
- Trial name
- FOUND (NCT04441814)
- Where
- Italy
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Pulmonary Nodule, Invasive Fungal Infections
Granulomatous Pneumocystis Pneumonia
The intra-alveolar form of Pneumocystis jiroveci pneumonia (PjP) is a common pathology in immunocompromised patients, particularly those infected with HIV. The diagnosis is based on the detection of Pj in a LBA.
- Conditions
- Pulmonary Nodule, Invasive Fungal Infections, Pneumocystis Jirovecii
- Trial name
- NC (NCT03731156)
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Tuberculosis
Prevalence of Latent Tuberculosis (TB) Infection Diagnosed by Interferon-gamma Release Assay and Tuberculin Skin Tests in Patients With Old Healed TB
We easily regard nodules and fibrosis in upper lobes of lung as TB sequelae. The aim of this study is to confirm the prevalence of latent TB infection diagnosed by interferon-gamma release assay and tuberculin skin tests in…
- Trial name
- NCT01099098
- Where
- South Korea
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Lung Cancer (Diagnosis), Nodule, Solitary Pulmonary
Non-Invasive Malignancy Classifiers Using Blood-Biomarkers for Lung Nodule Evaluation
The goal of the NIMBLE study is to evaluate blood-based biomarkers for lung cancer risk prediction in patients referred with a lung nodule.
- Trial name
- NIMBLE (NCT07623473)
- Testing
- Blood tests
- Where
- Denmark
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
High Risk Cancer
Standalone Observational Study Assessing the Performance of an AI/ML Tech-based SaMD on Chest LDCT Images (REALITY)
This is a Multinational, Multicenter, retrospective study for the evaluation of the standalone efficacy and safety of an Artificial Intelligence/Machine Learning (AI/ML) technology-based end-to-end Computer assisted…
- Trial name
- REALITY (NCT06576232)
- Testing
- Median LCS
- Where
- 5 sites in United States, Spain
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Median Technologies