Clinical trials: Pulmonary Nodules
Lung Cancer
Intra-op vs Pre-op Transbronchial Localization for Small Lung Nodule
Comparing pre-operative transbronchial localization under augmented fluoroscopy and intra-operative transbronchial localization using electromagnetic navigation bronchoscopy system for small lung nodules.
- Trial name
- NCT03793387
- Testing
- AF-guided endobronchial marking, ENB-guided endobronchial marking
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Lung Cancer
Piloting a Virtual Navigation (VN) System for Bronchoscopic Lung Nodule Sampling
The overall goal is to evaluate the role of a Virtual Navigation (VN) system (the Virtual Navigator) in the bronchoscopic evaluation and tissue sampling of lung cancer and other chest lesions at the Penn State Hershey Medical…
- Trial name
- NCT05599321
- Testing
- Virtual Navigation System
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Penn State University
Lung Diseases, Dyspnea
Effects of Transcutaneous Nerve Electrostimulation (TENS) of Acupuncture Points on Pulmonary Function and Dyspnea Symptoms in Patients With Pulmonary Nodules
The ancient use of acupuncture as a treatment modality of traditional Chinese medicine has also been proven effective in Western medicine.
- Conditions
- Lung Diseases, Dyspnea, Acupuncture
- Trial name
- LUNG TENS (NCT04051398)
- Testing
- transcutaneous nerve electrostimulation (TENS) of acupuncture points
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital Santa Marcelina
Lung Cancer (NSCLC)
Real-Time Non-Invasive Localization for Multiple Lung Nodules
This study compares real-time non-invasive localization and manual CT-guided needle localization for multiple lung nodules under 20 mm. It primarily aims to evaluate the successful resection rate of pulmonary nodules.
- Trial name
- NCT07257549
- Testing
- Manual needle localization, Real-time non-invasive localization
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Lung Tumor, Solitary Pulmonary Nodule
Feasibility of Multi-Energy Digital Radiography Detector for Lung Lesions Detection
A single-centre, industry sponsored, pilot study to assess the feasibility of Single Exposure Dual Energy Subtraction with a Multi-Energy digital radiography detector as an imaging platform for lung lesion detection.
- Trial name
- NCT03528733
- Testing
- Multi-Energy Digital Radiography Detector System
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- KA Imaging Inc.
Colon Cancer Liver Metastasis, Multiple Pulmonary Nodules
Combined Liver and Right Lung Resection for Colorectal Metastases by Means of J-shaped Thoracophrenolaparotomy
The purpose of this study is to determine whether J-shaped thoracophrenolaparotomy is effective in the surgical treatment of simultaneous liver and right lung metastases from colorectal cancer
- Trial name
- NCT02090816
- Testing
- Surgery of liver and lung
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- University of Milan
Lung Nodule, Solitary, Lung Nodule
Iriscope for the Diagnosis of Peripheral Pulmonary Lesions: a Multicentre Randomised Controlled Trial
A pulmonary nodule is a small mass detected in your lungs during a scan. When a nodule is suspicious, we need to determine its nature (benign or malignant). To do this, a bronchoscopy is performed.
- Conditions
- Lung Nodule, Solitary, Lung Nodule, Lung Cancer (Diagnosis)
- Trial name
- NCT07798362
- Testing
- Use of Iriscope via guide sheath to guide biopsies, Bronchoscopy
- Volunteers
- 140 people
- Sponsor
- Erasme University Hospital
Pulmonary Nodule, Solitary, Whole-genome Methylation Sequencing
Benign/Malignant Pulmonary Nodule Classification Based on High-throughput Whole-genome Methylation Sequencing(GM-seq)
Lung cancer is the first cancer in China in terms of morbidity and mortality. The problem of early diagnosis/treatment has always been concerned.
- Trial name
- NCT05415670
- Testing
- Whole-genome Methylation Sequencing(GM-seq)
- Where
- 2 sites in China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Geneplus-Beijing Co. Ltd.
Lung Cancer
Evaluating the Pulmonary Nodule With Imaging and Biomarkers
The study aims to determine if there are defining EBUS and confocal endoscopy features as well as exhaled alveolar gas VOC that can discriminate malignant pulmonary nodules or masses from benign etiology, thereby obviating…
- Trial name
- NCT01739881
- Testing
- Olympus Ultrathin Bronchofibervideoscope (XP260F)
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National University Hospital, Singapore
Carcinoma, Non-Small-Cell Lung
SLND or Not in cT1 GGO Invasive Lung Adenocarcinoma (ECTOP-1009)
This is a study from Eastern Cooperative Thoracic Oncology Project, numbered as ECTOP-1009. Systematically mediastinal lymph node dissection or not in clinical stage T1 ground-glass dominated invasive lung adenocarcinoma: a…
- Trial name
- NCT04527419
- Testing
- No mediastinal lymph node dissection
- Where
- China
- Volunteers
- 545 people
- Sponsor
- Fudan University
Lung Cancer
Deep Learning Model for Pure Solid Nodules Classification
The purpose of this study is to compare the predictive performance of a CT-based deep learning model for pure-solid nodules classification and compared with the tumor maximum standardized uptake value on PET in a multicenter…
- Trial name
- NCT05542992
- Testing
- CT-based deep learning model
- Where
- 5 sites in China
- Volunteers
- 260 people
- Sponsor
- Chang Chen
Pulmonary Nodules, Ground-glass Opacity
Percutaneous Robotic Navigation Microwave Ablation Versus CT-guided Microwave Ablation in the Treatment of Pulmonary Nodules With Ground-glass Opacity
1. To compare the precision of robot-guided microwave ablation and CT-guided microwave ablation in the treatment of ground-glass nodules. 2.
- Trial name
- NCT07389889
- Testing
- Robot, CT scan
- Volunteers
- 116 people
- Sponsor
- Fujian Medical University Union Hospital
Pulmonary Nodule Cm
Bronchoscopy Assisted by Electromagnetic Navigation (EMN) in the Diagnosis of Small Pulmonary Nodules
Due to CT screening, a lot of peripheral nodule not accessible to conventional endoscopy will be found. Electromagnetic navigation directed bronchoscopy (ENB) is a new technique needing validation.
- Trial name
- NCT01779388
- Testing
- Bronchoscopy
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- European Lung Cancer Working Party
Lung Nodule
Non-Invasive ctDNA Methylation Detection for Lung Nodule Patients
Low-dose computed tomography (LDCT) is recommended for early-stage lung cancer screening. However, it is often difficult to determine indolent lesions from more aggressive tumors without an invasive intervention or prolonged…
- Trial name
- NCT03685669
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Lung Nodule, Lung Mass
Cone Beam CT Guided Robotic Navigational Bronchoscopy
Navigational bronchoscopy (NB) is used to access peripheral and central parenchymal lung lesions via endobronchial and transbronchial approach.
- Conditions
- Lung Nodule, Lung Mass, Lung Cancer
- Trial name
- CBCTRNB (NCT05358041)
- Testing
- Robotic Bronchoscopy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Columbus Regional Health
Lung Nodules
Pneumothorax Post CT Lung Biopsy
A CT scan is performed after a lung biopsy in order to detect a Pneumothorax. We postulate that CT is more useful than chest radiography
- Trial name
- NCT00188409
- Testing
- CT scan
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Pulmonary Nodule Cm
Prognostic Value of miR-21 and miR-486 in Pulmonary Nodule Surgery
This study prospectively evaluated the prognostic value of microRNA-21 (miR-21) and microRNA-486 (miR-486) expression in patients with pulmonary nodules who underwent clock-guided minimally invasive surgery.
- Trial name
- NCT07060287
- Testing
- Clock-Guided Minimally Invasive Surgery
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Hospital of Hebei Medical University
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-making
The researchers are aimed to investigate the dynamic evolution of indeterminate pulmonary nodules by a long-term follow-up of patients with different characteristics.
- Trial name
- DEPICT (NCT04857333)
- Testing
- CT scan, Antibiotics, Surgical Resection
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- GuiBin Qiao
Lung Nodules, Pneumothorax Iatrogenic Postprocedural
Pneumothorax Safety of Pleural-Depth-Trimmed Hookwires for Lung Nodule Localization
The goal of this observational study is to learn about the pneumothorax risk associated with the Pleural-Depth-Trimmed Hookwire (PDTH) technique in patients undergoing Preoperative CT-Guided Lung Nodule Localization (POCTGL).
- Conditions
- Lung Nodules, Pneumothorax Iatrogenic Postprocedural, Propensity Score Matching
- Trial name
- NCT07300072
- Testing
- Preoperative CT-Guided Lung Nodule Localization with Pleural-Depth-Trimmed Hookwire (PDTH) Technique, Preoperative CTGuided Lung Nodule Localization with Patent Blue Vital Dye (PBVD) Localization Technique
- Where
- Taiwan
- Volunteers
- 1,072 people
- Sponsor
- Chung Shan Medical University
Non-Small Cell Lung Cancer, Stage IA Non-Small Cell Lung Cancer
Segmentectomy Versus Lobectomy for Deep Solid-Dominant Early-Stage NSCLC
SOLID is a multicenter, open-label, randomized, controlled, phase III non-inferiority trial comparing anatomic segmentectomy with lobectomy in patients with deeply located, solid-dominant, clinical stage IA non-small cell lung…
- Trial name
- SOLID (NCT07698990)
- Testing
- Anatomic Segmentectomy, Anatomic Lobectomy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Chest Hospital