Clinical trials: Pulmonary Nodules, open to volunteers
Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery
Video-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery
Right-sided double-lumen tubes are used for lung isolation during thoracoscopic surgery but can be difficult to position because of right bronchial anatomy.
- Conditions
- Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery, One-lung Ventilation, Lung Cancer
- Trial name
- NCT07849400
- Testing
- Continuous video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube
- Where
- 3 sites in China
- Volunteers
- 566 people
- Sponsor
- Diansan Su
Pulmonary Nodule, Pneumothorax
Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection
Brief Summary The goal of this clinical trial is to evaluate the safety and recovery outcomes of different tubeless strategies in adult patients undergoing uniportal video-assisted thoracoscopic (VATS) wedge resection who are…
- Conditions
- Pulmonary Nodule, Pneumothorax, Postoperative Complications
- Trial name
- NCT07395349
- Testing
- Conventional Chest Tube Drainage, Single Intraoperative Aspiration Tubeless, Double Intraoperative Aspiration Tubeless
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Lung Nodule
AI-based Low Dose CBCT Reconstruction for Clinical Application
The goal of this clinical trial is to learn if AI-based low dose CBCT reconstructed images can guide lung puncture effectively. The main questions it aims to answer are: 1.
- Trial name
- NCT06831617
- Testing
- AI-based low dose CBCT reconstructed images system, Conventional CBCT images system
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Pulmonary Nodules, Early-Stage Lung Cancer
Application of Electromagnetic Navigation System in Pulmonary Nodule Localization
This study aims to design and conduct a multicenter, prospective, randomized controlled post-market clinical trial to validate the clinical efficacy of high-precision electromagnetic navigation technology.
- Trial name
- NCT07595120
- Testing
- Electromagnetic Navigation-Guided Percutaneous Localization of Pulmonary Nodules, CT-Guided Percutaneous Localization of Pulmonary Nodules
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Pulmonary Nodules, Lung Neoplasms
A Multicenter Cohort Study of AI-Based Methods for Pulmonary Nodule Diagnosis and Follow-up
This is an observational, multicentre study. The primary objective of this study was to evaluate the diagnostic performance and clinical applicability of artificial intelligence models for pulmonary nodule segmentation…
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Artificial Intelligence (AI)
- Trial name
- NCT07815483
- Volunteers
- 16,880 people
- Sponsor
- Shanghai East Hospital
Lung Nodule, Lung Cancer
Biobank for the Identification of Biomarkers in Lung Cancer (BIRD, Biomarkers in Respiratory Disease)
The BIRD biobank aims at collecting clinical and biological data from patients suffering from a chronic respiratory disease. The lung cancer subpopulation will be divided into two cohorts to identify biomarkers of cancer.
- Trial name
- BIRD-NK (NCT06054854)
- Testing
- Extra blood sampling, Non-invasive or leftover samples or medical waste
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Toulouse
High-risk Lung Nodules
Immunoprevention for High-risk Lung Lesions
The main purpose of this study is to assess nadunolimab as an immunoprevention strategy for high-risk lung nodules in participants who are current or former tobacco smokers. The study may last up to 5 years for each participant.
- Trial name
- NCT07284485
- Testing
- Nadunolimab
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Robert Samstein
Lung Cancer (Diagnosis), Lung Nodule
A Randomized Controlled Trial Comparing Percutaneous CT-Guided Biopsy and Shape-Sensing Robotic-Assisted Bronchoscopy
The ENCOMPASS study is a post-market, multicenter, randomized controlled trial comparing two established approaches for obtaining a biopsy of small pulmonary nodules (≤2 cm): CT-guided percutaneous lung nodule biopsy and…
- Trial name
- ENCOMPASS (NCT07761351)
- Testing
- Shape-Sensing Robotic-Assisted Bronchoscopy with Cone-Beam CT (ssRAB with CBCT), CT-guided percutaneous lung nodule biopsy
- Where
- 3 sites in Germany, Switzerland and 1 more
- Volunteers
- 550 people
- Sponsor
- Intuitive Surgical
Lung Nodules
Bronchoscopic Navigation Robot-guided Dye Marking-assisted Thoracoscopic Pulmonary Nodule Resection
With the widespread use of low-dose spiral CT screening for the lungs, an increasing number of small nodules are being detected, and surgical resection is the preferred method for clinical intervention of pulmonary nodules.
- Trial name
- NCT06821451
- Testing
- Bronchoscopic navigation robot, Conventional electromagnetic navigation bronchoscope
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Ruijin Hospital
Pulmonary Nodule Cm
Sedation of Remazolam Combined With Afentanil in Non-intubated Thoracoscopic Pulmonary Surgery
Non-intubated Thoracoscopic surgery (NITS) is a newly emerging minimally invasive surgical technique in recent years . Compared with traditional intubation general anesthesia, it has the advantages of less trauma, faster recovery…
- Trial name
- R-A NITS (NCT06810843)
- Testing
- Remazolam combined with afentanil for non-intubated thoracoscopic surgery, Propofol combined with afentanil in non-intubated thoracoscopic surgery
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Qianfoshan Hospital
Pulmonary Nodules, Lung Neoplasms
Deep Learning Time-Series Prediction of Long-Term Growth Patterns of Pulmonary Ground-Glass Nodules Using Serial CT
Pulmonary ground-glass nodules (GGNs) are commonly found on chest CT scans. Some stay stable for years, while others slowly or rapidly turn into lung cancer.
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Adenocarcinoma of Lung
- Trial name
- GGN-Trajectory (NCT07647692)
- Testing
- Serial Thin-Slice Chest CT
- Where
- China
- Volunteers
- 4,750 people
- Sponsor
- Peking University People's Hospital
Lung Nodules
Pre-Emptive Parecoxib Sodium for Pain Control During CT-Guided Lung Nodule Localization
Before undergoing minimally invasive lung surgery, patients with small lung nodules often need a procedure called "CT-guided hook wire localization." This involves using a CT scanner to help doctors place a tiny wire in the lung…
- Trial name
- PEARL (NCT07675473)
- Testing
- PARECOXIB SODIUM, 0.9 % Normal Saline
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Long Jiang
Solitary Pulmonary Nodule, Lung Neoplasms
Radiomics for Distinguishing Benign and Malignant Lung Nodules
Differentiating between benign (non-cancerous) and malignant (cancerous) pulmonary nodules is a critical step in determining appropriate patient management and cancer treatment planning.
- Conditions
- Solitary Pulmonary Nodule, Lung Neoplasms, Multiple Pulmonary Nodules
- Trial name
- NCT07852000
- Volunteers
- 255 people
- Sponsor
- Assiut University
Pulmonary Nodules, Lung Neoplasms
Longitudinal AI-Assisted Management of Indeterminate Pulmonary Nodules
Patients with indeterminate lung nodules often face a choice between continued CT surveillance and invasive investigation. This trial compares management with or without access to an AI report that matches nodules across real…
- Trial name
- NCT07895277
- Testing
- AI-Assisted Longitudinal CT Assessment and Pulmonary Nodule Management
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lung Cancer
Safety and Efficacy Evaluation of Cryoablation in the Treatment of Ground-Glass Nodules
Lung cancer is the leading cause of cancer-related mortality worldwide, making early diagnosis and intervention critical. With the widespread adoption of low-dose computed tomography (LDCT) screening, the detection rate of…
- Trial name
- NCT07232433
- Testing
- Cryoablation
- Where
- 2 sites in China
- Volunteers
- 90 people
- Sponsor
- Ruijin Hospital
Lung Cancer (Locally Advanced or Metastatic)
Pemefolacianine for IMI of Lung Cancer
The aim of this Phase 1b study is to investigate the safety and fluorescence signal of a single dose of Pemefolacianine for Injection, a novel fluorescence imaging agent developed by Nanjing Nuoyuan Medical Devices Co., Ltd…
- Trial name
- NCT07772895
- Testing
- Pemefolacianine Cohort 1 in Part A, Pemefolacianin Cohort 2 in Part B
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Sunil Singhal
Lung Cancer Patients
SERS-Based Serum Molecular Spectral Detection of Invasive Lung Cancer
Surgery is the main treatment for early lung cancer. It is worth noting that there are significant differences in postoperative prognosis and surgical methods between microinvasive cancer and early-stage invasive cancer.
- Trial name
- NCT06775015
- Testing
- Serum Raman spectroscopy intelligent diagnostic system
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fuzhou General Hospital
Pulmonary Nodule, Liposomal Bupivacaine
Effect of Intercostal Nerve Block With Liposomal Bupivacaine on Quality of Recovery in VATS Partial Pneumonectomy
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive approach for partial pneumonectomy, but postoperative pain remains a major challenge affecting recovery.
- Trial name
- NCT07512635
- Testing
- Bupivacaine Hydrochloride, Bupivacaine liposome
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Sanming First Hospital
The Efficacy and Safety of SBRT in MPLC
The Effectiveness and Safety of SBRT in the Treatment of Patients With MPLC After Surgery (SMILE)
To prospectively evaluate the effectiveness and safety of SBRT in the treatment of residual malignant pulmonary nodules after lung cancer, and is committed to providing new treatment options for patients with multiple primary…
- Trial name
- SMILE (NCT05113017)
- Testing
- NO Intervention
- Where
- 5 sites in China
- Volunteers
- 40 people
- Sponsor
- Fang Wu
Lung Nodules
The Effect of Acupuncture on Pulmonary Function Recovery Following Lung Resection
Background and Purpose: Lung resection surgery is the standard treatment for early-stage lung adenocarcinoma, but it often leads to reduced lung volume and postoperative pain, which can hinder pulmonary recovery.
- Trial name
- NCT07443540
- Testing
- Acupuncture Therapy, Incentive Spirometry (Standard Rehabilitation)
- Volunteers
- 56 people
- Sponsor
- Chung Shan Medical University