Clinical trials: Pulmonary Procedures
Mental Health Wellness, Psychological Security
Ultra-brief Online Mindfulness-based Intervention During COVID-19 Movement Control Order
The federal government of Malaysia implemented a nationwide Movement Control Order (MCO) to control the COVID-19 outbreak. The MCO, however, has been found to have a negative impact on people's mental wellbeing.
- Conditions
- Mental Health Wellness, Psychological Security, Psychological Distress
- Trial name
- NCT04536441
- Testing
- Ultra Brief Online Mindfulness-based Intervention, Control
- Where
- Malaysia
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman
Asthma
Using Mobile Phones to Improve Adherence to Inhaled Steroids
This study has two main goals. The first goal is to test whether a mobile phone intervention can increase adherence to daily inhaled steroid medications in African American adolescents prescribed this type of medication by…
- Trial name
- ADEPT4 (NCT01710059)
- Testing
- Asthma Supervision, Mobile Phone, Inhaled Corticosteroid Mobile Phone Application
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Rush University Medical Center
Pulmonary Nodules, Lung Cancer (Diagnosis)
The Percutaneous Interventional Surgery Control System for Pulmonary Nodule Biopsy
This prospective, single-center, non-inferiority, randomized controlled clinical trial aims to evaluate the efficacy and safety of a percutaneous interventional surgical control system in performing percutaneous needle biopsy of…
- Conditions
- Pulmonary Nodules, Lung Cancer (Diagnosis), Percutaneous Needle Biopsy, Transthoracic Needle Biopsy
- Trial name
- NCT07277088
- Testing
- Percutaneous Needle Biopsy with Interventional Surgical Control System, Conventional Manual Percutaneous Needle Biopsy
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Jiayuan Sun
Persistent Atrial Fibrillation
FIH Study of PFLotus in Persistent Atrial Fibrillation
Single-shot pulsed-field ablation (PFA) catheters maximize pulmonary vein isolation (PVI) efficiency but are limited for focal or linear ablation.
- Trial name
- PFLotus- FIH (NCT07301190)
- Testing
- Pulse field ablation with the PFLotus catheter
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Third People's Hospital of Chengdu
Stress, Burnout
RECHARGE: A Brief Psychological Intervention to Build Resilience in Healthcare Workers During COVID-19
The healthcare industry is inherently demanding, stressful, and, at times, emotionally draining. On a typical day, many workers must make rapid and critical decisions, manage numerous demands, team conflicts, and challenging…
- Conditions
- Stress, Burnout, Anxiety, Depression
- Trial name
- NCT04531774
- Testing
- RECHARGE, Self Study
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Naser Morina
Sepsis, Bacteraemia
Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care
Acute illness is the most common presentation of children attending ambulatory care settings. Serious infections (e.g. meningitis, sepsis, pyelonephritis, pneumonia) are rare, but their impact is quite large (increased morbidity…
- Conditions
- Sepsis, Bacteraemia, Meningitis, Abscess
- Trial name
- ERNIE2 (NCT02024282)
- Testing
- Use of C-reactive protein (CRP) point of care test, Brief intervention and parent leaflet, Finger Pulse Oximeter
- Where
- 2 sites in Belgium
- Volunteers
- 8,962 people
- Sponsor
- KU Leuven
Pulmonary Surgical Procedures
Hyperpolarized Xenon MRI for Assessment of Pulmonary Function in Lung Transplant
This study compares the equivalence of hyperpolarized 129Xe MRI to 133Xe scintigraphy for the evaluation of pulmonary function in patients being evaluated for lung transplant.
- Trial name
- NCT03418090
- Testing
- 129Xe MRI, 133XE scintigraphy
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Polarean, Inc.
COPD Symptoms After Coil Procedure
Chronic Obstructive Pulmonary Disease (COPD) Co-Pilot AIR Substudy of CLN0014
The purpose of undertaking CLN0020, which was a Substudy of the European Coil registry (CLN0014), was to investigate the use of COPD Co-Pilot AIR™, a COPD disease management program manufactured and operated by HGE Health Care…
- Trial name
- Co-Pilot Air (NCT03267992)
- Testing
- COPD Co-Pilot AIR App
- Where
- 2 sites in Switzerland
- Volunteers
- 9 people
- Sponsor
- Boston Scientific Corporation
Rehabilitation, Post-Acute COVID-19 Syndrome
RCT Long COVID-19 Rehabilitation
The Coronavirus 2019 (COVID-19) pandemic has resulted in at least four million infections in Norway. The vast majority of cases are diagnosed and followed up in the community, but some with extensive symptoms and large degree of…
- Conditions
- Rehabilitation, Post-Acute COVID-19 Syndrome, Post-Infectious Disorders
- Trial name
- NCT06085911
- Testing
- One day course, Individual follow-ups
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital of North Norway
Incidental Lung Nodule
Lung Nodule Characterization by Artificial Intelligence Techniques
Management of incidental lung nodule is difficult and mainly based on simple morphometric characteristics such as maximum size and shape.
- Trial name
- CARANOD-IA (NCT03843164)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Anesthesia
Effects of One-handed and Two-handed Mask Ventilation Techniques on Global and Regional Lung Ventilation
Two-handed mask ventilation has been shown to provide higher tidal volume than one-handed mask ventilation. The effects of the two techniques on respiratory mechanics during induction of general anesthesia, however, still need to…
- Trial name
- NCT04617665
- Testing
- One-handed mask ventilation, Two-handed mask ventilation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fudan University
Fetal Distress
Prediction of Fetal Lung Maturity
Diabetes is the most common medical complication of pregnancy in the united states four to five percent of pregnancies are complicated by diabetes.
- Trial name
- NCT03159234
- Testing
- fetal lung volume, pulmonary artery resistance index, Fetal adrenal gland volume:
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Assiut University
COVID-19, SARS-CoV-2
PEP Flute-selfcare in COVID-19
Most research on the coronavirus SARS-CoV-2 and COVID-19 disease relate to screening measures, development of vaccines and optimising treatment of hospitalised patients.
- Trial name
- PEP-CoV (NCT04530435)
- Testing
- PEP flute
- Where
- Denmark
- Volunteers
- 378 people
- Sponsor
- Bispebjerg Hospital
Asthma
Asthma Intervention Research (AIR) Trial
The purpose of this study is to demonstrate the effectiveness and safety of the Alair System for the treatment of asthma. This will be a multicenter, randomized controlled study comparing the effects of treatment with the Alair…
- Trial name
- NCT00214526
- Testing
- Bronchial thermoplasty with the Alair System, Conventional therapy with ICS+LABA
- Volunteers
- 112 people
- Sponsor
- Asthmatx, Inc.
Cancer, Pleural Neoplasms
Safety, Efficacy, and Side Effects Study of Interventional Cryotherapy in the Pleural Space("ICE PLS")
The purpose of this study is to evaluate the safety, efficacy, and side effects of the CryoSpray Ablation(TM) System (CSA(TM) System) to treat neoplastic lesions on the parietal pleural surface.
- Trial name
- NCT00747916
- Testing
- CryoSpray Ablation (TM) System
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- CSA Medical, Inc.
Pulmonary Disease, Chronic Obstructive
Tiotropium 18ug Inhalation Capsule Using a Handihaler® Among Korean COPD Patients
This is a descriptive observational open non-comparative study of the safety and efficacy of tiotropium inhalation capsule given at 18mcg once a day for 30 days among Korean patients with COPD.
- Trial name
- NCT00620516
- Where
- 71 sites in South Korea
- Volunteers
- 3,008 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive
TARA Working Prototype [Version 2]: Feasibility Study
TARA is a Digital Behaviour Change Intervention (DBCI) for Individuals with COPD (IwCOPD), which has been designed using a Human-Centred Design (HCD) methodology.
- Trial name
- NCT04320524
- Testing
- Technology-Assisted Respimat Adherence Digital Behaviour Change Intervention
- Sponsor
- Boehringer Ingelheim
Lung Cancer, Small Cell
Regulatory Hycamtin(Oral) PMS
Non-interventional, open-label, single group, multicentric post-marketing surveillance to monitor the safety and effectiveness of Topotecan administered in Korean patients according to the prescribing information
- Trial name
- Hycamtin PMS (NCT01037023)
- Testing
- Topotecan
- Where
- 2 sites in South Korea
- Volunteers
- 92 people
- Sponsor
- GlaxoSmithKline
Lung Cancer (Diagnosis), Smoking Cessation
Impact of Lung Cancer Screening With Chest Scans Combined With Coaching on Smoking Cessation in Heavy Smokers
Lung cancer is common and serious, but when detected early, the chances of recovery are significantly better. Tobacco use is the leading cause.
- Conditions
- Lung Cancer (Diagnosis), Smoking Cessation, Lung Neoplasm
- Trial name
- NCT07860359
- Testing
- Image-Based Counseling, Smoking Cessation Coaching, Low-Dose Chest Computed Tomography (LDCT)
- Where
- Switzerland
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
COPD, Respiratory Disease
Phase 1 Study Into Pharmacokinetics and Food Effect of Vapendavir in Healthy Participants and Participants With COPD
Vapendavir (VPV) is potent virostatic antiviral agent active against all known enterovirus species. VPV binds to the viral capsid, thereby inhibiting viral attachment to the target cell and, independently, preventing release of…
- Conditions
- COPD, Respiratory Disease, Lower Respiratory Disease, Pulmonary Disease
- Trial name
- NCT05962645
- Testing
- Vapendavir
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Altesa Biosciences, Inc.
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