Clinical trials: Pulmonary Procedures
Long COVID, Long Covid19
Narrative Intervention for Long COVID-19 (NICO)
This T1 proof of concept trial is designed to test the Narrative Intervention for Long COVID-19 intervention.
- Trial name
- NICO (NCT06091293)
- Testing
- Narrative Intervention for Long COVID-19 (NICO)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Colorado, Denver
COPD
COPD Access to Pulmonary Rehabilitation Intervention
Persons with COPD have significant functional disability but cannot access rehabilitative treatment at hospital-based conventional pulmonary rehabilitation (PR) programs.
- Trial name
- CAPRI (NCT03794921)
- Testing
- Every Step Counts
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- VA Office of Research and Development
Long COVID
Study to Investigate the Health Benefits of a Quercetin/Curcumin-Based Supplement for Mild to Moderate Long COVID-19 Symptoms
This pragmatic clinical study aims to evaluate the efficacy and tolerance of a combined quercetin/curcumin supplement in adults experiencing mild to moderate symptoms of Long COVID-19.
- Trial name
- NCT06974058
- Testing
- Nasafytol® (Quercetin/Curcumin Supplement)
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Dyspnea, Respiratory Insufficiency
Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness in Patients With Advanced Disease
Episodic breathlessness is a common and distressing symptom in patients with advanced disease such as cancer, chronic obstructive pulmonary disease (COPD) and chronic heart failure.
- Conditions
- Dyspnea, Respiratory Insufficiency, Neoplasms, Pulmonary Disease, Chronic Obstructive
- Trial name
- CoBeMEB (NCT04630743)
- Testing
- Cognitive and Behavioral intervention for the Management of Episodic Breathlessness
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Cologne
Persistent Atrial Fibrillation, Pulsed-field Ablation
Pulsed-field Ablation in Patients With Persistent Atrial Fibrillation
Since a new method called pulsed-field ablation (PFA) has emerged, allowing significantly simpler, safer, and faster creation of ablative lesions in paroxysmal AF and PsAF (13), redefining the "optimal" ablation approach started…
- Trial name
- PIVCO (NCT05922917)
- Testing
- pulsed-field ablation
- Where
- 3 sites in Czechia
- Volunteers
- 518 people
- Sponsor
- České Budějovice Hospital
Pulmonary Disease, Chronic Obstructive, Breathing Exercises
Effects of an Exercise Rehabilitation Programme With a Nasal Inspiratory Restriction Device in COPD Patients
This study evaluates the effects of a nasal restriction device for inspiratory muscle training (FeelBreathe) after 8 weeks of exercise intervention on exercise capacity, quality of life, dyspnea and inspitarotory muscle strength…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Breathing Exercises, Exercise Tolerance
- Trial name
- EPOC_2_0 (NCT03936348)
- Testing
- Exercise training program with and without FB
- Volunteers
- 16 people
- Sponsor
- University of Cadiz
ARDS
Three Methods for Best PEEP Determination Compared With PEEP Determination Guided by Adult Respiratory Distress Syndrome (ARDS) Network
To compare the best Positive End Expiratory Pressure (PEEP) as determined by one of three commonly used clinical approaches for best PEEP determination, with PEEP guided by the ARDS network algorithm.
- Trial name
- NCT01742715
- Testing
- PEEP by Best oxygenation, PEEP by Best Compliance, PEEP by Esophageal pressure
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Wolfson Medical Center
Anesthesia
Intraoperative Measurement of Lung Elastance and Transpulmonary Pressure Using Two Different Methods.
Classically lung elastance and transpulmonary pressure are measured from the difference in tidal variations of airway pressure subtracted by tidal variations i esophagus pressure divided by the tidal volume.
- Trial name
- Lungbaro (NCT02830516)
- Testing
- Measurement of lung elastance by two methods
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Stefan Lundin
Thoracic Anesthesia, One Lung Ventillation (OLV)
Association Between One Lung Ventilation and Myocardial Injury Markers (Troponin T and I) in Thoracic Surgical Procedures (OLVTIS)
This prospective single-group cohort study aims to investigate the association between the One-Lung Ventilation (OLV) technique and myocardial injury, as measured by postoperative Troponin T and Troponin I levels, in patients…
- Trial name
- OLVTIS (NCT07302243)
- Where
- Indonesia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitas Jenderal Soedirman
Atopic Dermatitis, Food Allergy in Children
Preventing Atopic Dermatitis and ALLergies in Children
The primary objective is of the PreventADALL study is to test if primary prevention of allergic diseases is possible by simple and low cost strategies, and secondary to asses the impact of xenobiotic exposure and microbiota in…
- Conditions
- Atopic Dermatitis, Food Allergy in Children, Asthma, Rhinitis, Allergic
- Trial name
- PreventADALL (NCT02449850)
- Testing
- Food intervention, Skin care
- Where
- Norway
- Volunteers
- 2,701 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Lung Neuroendocrine Neoplasm, GEP Neuroendocrine Tumor
A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus, Sunitinib or PRRT (CABOTEM)
The aim of CABOTEM study is to demonstrate the safety and activity of the Cabozantinib and Temozolomide combination in Lung and GEP-NENs patients, progressing after a first line therapy, including target therapies (everolimus…
- Trial name
- CABOTEM (NCT04893785)
- Testing
- Cabozantinib and Temozolomide
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- National Cancer Institute, Naples
Intra-abdominal Hypertension, Acute Respiratory Distress Syndrome (ARDS)
End-expiratory Transpulmonary Pressure-guided vs Electrical Impedance Tomography-guided PEEP Titration Methods in Patients With Intra-abdominal Hypertension Combined With Acute Respiratory Distress Syndrome: a Randomized Crossover Controlled Study
This study aims to adopt a randomized crossover design to compare the effects of end-expiratory transpulmonary pressure-guided PEEP titration and EIT-guided PEEP titration on local lung ventilation, shunt, dead space, and…
- Trial name
- NCT06697717
- Testing
- Transpulmonary Pressure-Guided PEEP Titration in IAH and ARDS Patients, EIT-Guided PEEP Titration in IAH and ARDS Patients
- Where
- China
- Volunteers
- 15 people
- Sponsor
- XiaoJing Zou,MD
Pulmonary Valve Insufficiency, Pulmonary Regurgitation
COMPASSION - COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal THV
To assess the safety and effectiveness of pulmonic THV implantation in subjects with dysfunctional RVOT conduit requiring treatment for moderate or severe pulmonary regurgitation (≥3+ pulmonary regurgitation) and/or RVOT conduit…
- Conditions
- Pulmonary Valve Insufficiency, Pulmonary Regurgitation, Dysfunctional RVOT Conduit, Pulmonary Obstruction
- Trial name
- NCT00676689
- Testing
- SAPIEN Transcatheter Valve Implantation
- Where
- 7 sites in United States
- Volunteers
- 81 people
- Sponsor
- Edwards Lifesciences
Monitored Anesthesia Care, Respiratory Monitoring
Importance of Integrated Pulmonary Index in Pediatric Endoscopy
Integrated Pulmonary Index (IPI) is a tool that provides numerical values on a scale of 1-10 based on physiological parameters such as peripheral oxygen saturation (SpO2), pulse rate, respiratory rate, end-tidal carbon dioxide…
- Trial name
- NCT05137574
- Testing
- Integrated Pulmonary Index (IPI) monitoring, propofol, ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Lung-protective Ventilation, Respiratory Function Monitor
Optimization of Ventilation Strategies in Preterm and Term Infants in a Single-center Intervention Study
This study was a non-blinded, non-randomized intervention study in a single-center clinical setting, analyzing ventilation quality with and without RFM visibility.
- Trial name
- NCT05512689
- Testing
- Ventilations while using a respiratory function monitor
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cancer, Lung, Cancer, Head and Neck
A Stepped Care Intervention to Reduce Disparities in Mental Health Services Among Cancer Patients and Caregivers
Medically under-served (i.e., low-income, uninsured, underinsured) cancer patients generally encounter significant disparities in accessing care for their mental health needs while undergoing toxic treatments that provide…
- Trial name
- NCT03016403
- Testing
- Stepped-Care Intervention, Enhanced Usual Care
- Where
- 5 sites in United States
- Volunteers
- 535 people
- Sponsor
- University of Colorado, Denver
COPD
Breathing Control in Patients With Chronic Obstructive Pulmonary Disease (COPD)
There is a demand for explorative and comparative studies on various non-pharmaceutical efforts in treating and helping chronic obstructive pulmonary disease patients. This study has been developed in light of this need.
- Trial name
- NCT01512043
- Testing
- Breathing control
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Lovisenberg Diakonale Hospital
Lung Carcinoma, Metastatic Malignant Neoplasm in the Lung
Panitumumab-IRDye800 in Detecting Cancer in Participants With Lung Cancer During Surgery
This phase I/II trial studies the best dose and timing of panitumumab-IRDye800 in detecting cancer in participants with lung cancer during the surgery.
- Conditions
- Lung Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8
- Trial name
- NCT03582124
- Testing
- Near-Infrared Fluorescence Imaging, Panitumumab-IRDye800, Pharmacokinetic Study
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Carotid Stenosis, Coronary Artery Disease
Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients
Prospective, single-center, clinical registry of patients with symptomatic/critical carotid artery stenosis at risk of stroke coexisting with unstable or multivessel severe coronary artery disease and/or severe valvular heart…
- Conditions
- Carotid Stenosis, Coronary Artery Disease, Valvular Heart Disease, Myocardial Infarction
- Trial name
- SIM-GUARD (NCT04973579)
- Testing
- Simutaneous (single anaesthesia) carotid artery stenting with MicroNet covered stent (CGuard) and cardiac surgery (CABG or surgical valve replacement / repair procedure)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- John Paul II Hospital, Krakow
Neoplasms, Geriatric Assessment
Oncogeriatric Intervention and Follow-up at Home
The study is a randomized study of patients living in four municipalities in Eastern Jutland. After geriatric assessment half of the patients will be offered a tailor-made intervention in their homes.
- Conditions
- Neoplasms, Geriatric Assessment, Lung Neoplasms, Colorectal Neoplasms
- Trial name
- NCT02837679
- Testing
- Geriatric Follow up
- Where
- Denmark
- Volunteers
- 350 people
- Sponsor
- Aarhus University Hospital
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