Clinical trials: Pulmonary Procedures
Chronic Obstructive Pulmonary Disease
Tiotropium In Early Chronic Obstructive Pulmonary Disease Patients in China
Chronic obstructive pulmonary disease (COPD) is one of the commonest respiratory diseases. During the early stage of COPD, patients only have mild respiratory symptoms or signs which may lead to under-diagnosis of the disease.
- Trial name
- Tie-COPD (NCT01455129)
- Testing
- Tiotropium
- Where
- 25 sites in China
- Volunteers
- 841 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Ventilator-Induced Lung Injury, Acute Respiratory Distress Syndrome
Comparing Mechanical Power in Different Inspiratory Times
We aimed to compare mechanical power and energy values using geometric methods at varying inspiratory rise times.
- Trial name
- NCT06413472
- Testing
- Mechanical ventilator adjustment for PCV, Mechanical ventilator adjustment for VCV
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
COPD (Chronic Obstructive Pulmonary Disease)
Development And Evaluation of An Adaptive Web-Based Intervention for COPD
Narrative-based tiered asynchronous psychosocial and behavioral whole health support for people adjusting to living with COPD. The intervention is administered by experienced LCSWs under the PI's supervision.
- Trial name
- NCT06770777
- Testing
- Tiered whole health support for people living with COPD
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Acute Cardiogenic Pulmonary Edema
OUT-OF-HOSPITAL CPAP STUDY
Evaluate efficacy and safety of CPAP in a randomised standard treatment controlled study, in out-of-hospital patients with acute cardiogenic pulmonary edema.
- Trial name
- NCT00439075
- Testing
- CPAP, standard treatment
- Where
- France
- Volunteers
- 124 people
- Sponsor
- University Hospital, Toulouse
Covid19, Mental Health Issue
CRISOL Contigo: a Multi-level Intervention to Reduce the Disproportionate Toll of COVID-19 Among Latino Communities in Philadelphia.
Latinos have been one of the racial/ethnic groups most impacted by the COVID-19 pandemic, and evidence of effective strategies to curb the pandemic, reduce disparities, and mitigate its impact is lacking and very urgent.
- Conditions
- Covid19, Mental Health Issue, Violence
- Trial name
- CRISOL Contigo (NCT04646616)
- Testing
- Community popular opinion leader (POL) based intervention
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Drexel University
Asthma
Environmental Intervention to Reduce Allergens in Urban Schools and Childhood Asthma
The investigators aim to pilot the role of school based intervention consisting of enhanced integrated pest management, classroom air purifiers and cleaning improves asthma morbidity.
- Trial name
- NCT01913795
- Testing
- integrated pest management, air purifier
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Asthma
physicAl aCtiviTy In minOrity womeN With Asthma Intervention
The ACTION intervention: physicAl aCtiviTy In minOrity womeN with asthma is a 3lifestyle physical activity intervention refined to be applicable for sedentary African American (AA) women with asthma.
- Trial name
- ACTION (NCT03265665)
- Testing
- ACTION Intervention, Enhanced usual care
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Illinois Chicago
Non Small Cell Lung Cancer Metastatic, Newly Diagnosed NSCLC
Liquid Biopsy Based NGS in Newly Diagnosed NSCLC
This study expands the application of an electronic health record (EHR) "nudge" used to prompt physicians' clinical practice to order molecular testing at the time of initial diagnosis for patients with specific types of advanced…
- Conditions
- Non Small Cell Lung Cancer Metastatic, Newly Diagnosed NSCLC, Non-Squamous Non-Small Cell Neoplasm of Lung
- Trial name
- iNUDGE (NCT05853887)
- Testing
- iNUDGE
- Where
- 6 sites in United States
- Volunteers
- 260 people
- Sponsor
- Charu Aggarwal
COVID - 19, Renal Transplant
Safety and Effectiveness of a Remdesivir Treatment to Prevent Severe COVID-19 in Kidney Transplant Patients
Since the start of the COVID-19 pandemic, the approach to solid organ transplantation has evolved. Transplants using organs (excluding lungs) from COVID-19-positive donors have shown short-term safety, but there is limited data…
- Conditions
- COVID - 19, Renal Transplant, SARS CoV 2 Infection
- Trial name
- COVIDKIDNEY (NCT07197164)
- Testing
- Remdesivir (RDV)
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Lung Neoplasms, Pancreatic Neoplasms
Diagnosis of Multiple Cancer and Monitoring of Minimal Residual Tumors After Treatment Using Blood and High-Sensitivity Genetic Analysis Techniques
This is a combined prospective and retrospective observational study aiming to validate a highly sensitive and specific blood-based method for the early diagnosis and post-treatment monitoring of multiple cancers.
- Conditions
- Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms
- Trial name
- NCT07035587
- Testing
- Serial Blood Sampling for Molecular Profiling, One-Time Blood Sampling for Molecular Profiling
- Where
- South Korea
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Asthma Control, Pulmonary Function
Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study
The primary goal of this study is to investigate the comparative long-term (i.e., 1-year) effectiveness of energy recovery ventilators (ERVs) and portable air cleaners (PACs) in reducing indoor air pollutants and mold levels and…
- Conditions
- Asthma Control, Pulmonary Function, Quality of Life, Stress
- Trial name
- NCT07196436
- Testing
- Energy Recovery Ventilator, Portable Air Cleaner
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas at Arlington
Pulmonary Diseases, Ophthalmological Diagnostic Techniques
Assisting Pulmonary Disease Diagnosis With Ophthalmic Artificial Intelligence Technology
This study intends to collect ophthalmologic examination results, pulmonary examination results and related indexes from patients with pulmonary disease and control populations, and combine big data analysis and artificial…
- Conditions
- Pulmonary Diseases, Ophthalmological Diagnostic Techniques, Artificial Intelligence
- Trial name
- NCT05847894
- Testing
- Ophthalmic examination, Pulmonary Examination
- Where
- 4 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Asthma
The Community United to Challenge Asthma
This study compares an asthma self-management intervention, delivered to the family and tailored to their needs and cultural beliefs, to standard asthma education on two risk factors for asthma exacerbations in high-risk Puerto…
- Trial name
- Project CURA (NCT01065883)
- Testing
- community health worker, mailed information
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rush University Medical Center
COPD, Obesity &Amp; Overweight
The Impact of a Weight Reduction Intervention on Clinical Outcomes in Patients With Obesity and COPD
Obesity and COPD are increasingly common and often coexist, worsening health outcomes such as reduced lung function, exercise capacity, and increased systemic inflammation.
- Trial name
- NCT07159594
- Testing
- Energy restriction
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
Carcinoma, Non-Small-Cell Lung
Cerebrospinal Fluid Immune Microenvironment Mechanism in Anaplastic Lymphoma Kinase Positive Lung Cancer Patients
This is an an interventional study to explore the mechanism of cerebrospinal fluid immune microenvironment in patients with advanced anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer with brain metastases…
- Trial name
- NCT06697990
- Testing
- Iruplinalib
- Volunteers
- 12 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Anxiety Disorders, Post Traumatic Stress Disorder
Psychological Impact of Admission With Covid-19 During the SARS-CoV-2 Pandemic: Naturalistic Cohort Study With a Digital Intervention
Studies have shown that admission to hospital during a coronavirus epidemic is associated with increased levels of anxiety, depression and panic disorder.
- Conditions
- Anxiety Disorders, Post Traumatic Stress Disorder, Depressive Disorder, Covid19
- Trial name
- FeelGood (NCT04449627)
- Testing
- Feeling Good Digital App
- Volunteers
- 125 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
COPD
Singing for Wellness: Is Singing a Useful Way of Supporting People in South Devon to Self-manage Aspects of Their COPD
The aim of this study is to explore whether singing is a useful way of supporting people in South Devon to self manage aspects of their COPD and associated social isolation.
- Trial name
- NCT04360642
- Testing
- singing
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Torbay and South Devon NHS Foundation Trust
Percutaneous Lung Ablation
A Clinical Trial of Percutaneous Lung Ablation Using Navigational Positioning Robot-assisted Procedures
The purpose of the trial is to exploratively evaluate the safety and efficacy of the Puncture Surgery Navigation and Positioning System for CT-guided percutaneous lung ablation procedures for multiple ground glass nodules.
- Trial name
- NCT07105813
- Testing
- Navigational Positioning System for Puncture Surgery
- Volunteers
- 30 people
- Sponsor
- Xiaolong Yan, Dr.
Pneumonia
Ventilator Associated Pneumonia and Late Complications of Percutaneous Tracheostomy
The purpose of this study is to investigate the incidence of ventilator associated pneumonia and late complications by comparing two different cannulas and two different percutaneous tracheostomy techniques.
- Trial name
- NCT00184925
- Testing
- Tracheostomy, cannula with subglottic drainage
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Radboud University Medical Center
Myocarditis
A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.
The purpose of this study is to learn about the safety and effects of the vaccine (called COMIRNATY) for the potential prevention of COVID-19. This study is seeking participants who: 1. Are age <21 years. 2.
- Trial name
- NCT05295290
- Testing
- Cardiac Imaging
- Where
- 18 sites in United States
- Volunteers
- 319 people
- Sponsor
- Pfizer
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