Clinical trials: Pulmonary Procedures
COPD
Impairments That Affect Correct Inhaler Use in COPD
INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: 1. Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic…
- Trial name
- INHALE (NCT06135324)
- Where
- 9 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- COPD Foundation
Pulmonary Emphysema
Post-Market Clinical Evaluation of the Zephyr Valve 5.5-LP EBV
This is a Post-Market Evaluation of the Zephyr Valve 5.5-LP EBV to assess Treated Lobar Volume Reduction (TLVR), changes in lung function and the safety profile of the Zephyr Valve treatment with the use of at least one Zephyr…
- Trial name
- NCT04161235
- Testing
- The Pulmonx Zephyr Endobronchial Valve (EBV) 5.5- LP
- Where
- 3 sites in Germany, Switzerland and 1 more
- Volunteers
- 2 people
- Sponsor
- Pulmonx Corporation
Severe Asthma
Real-world Study Assessing Efficacy of TezepeLumaB in Patients With Severe Asthma Regardless of Phenotype in Russia
ELBRUS is a 12-month (52-week), multi-centre, prospective, non-comparative and non-interventional (observational), post-reimbursement real-world evidence study that will assess patient-reported outcomes after tezepelumab…
- Trial name
- ELBRUS (NCT06566885)
- Where
- 15 sites in Russia
- Volunteers
- 125 people
- Sponsor
- AstraZeneca
COVID-19, Mental Health
Impact of a Minimal Psychoeducational Intervention on Anxiety Among Hospitalized COVID-19 Patients in Denmark
Background: There is limited knowledge on the psychological implications of COVID-19 among hospitalized patients and their close relatives.
- Conditions
- COVID-19, Mental Health, Psychoeducation, Anxiety
- Trial name
- PISCA (NCT04351789)
- Testing
- Psychoeducational intervention
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Healthy Participants, Intrusive Memories
Understanding Reactions to Emotional Material in the Media During COVID-19
This feasibility study aims to adapt a protocol usually run in the laboratory in the Psychology Department for healthy participants (including the trauma film paradigm (James et al., 2016) and a simple cognitive task…
- Trial name
- NCT04608097
- Testing
- Simple cognitive task intervention
- Where
- Sweden
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Cystic Fibrosis, Chronic Obstructive Pulmonary Disease (COPD)
Prevalence and Treatment of Urinary Incontinence in Women With Cystic Fibrosis and Chronic Obstructive Pulmonary Disease
Women with chronic lung disease characterised by chronic cough report urinary incontinence. Recently there have been reports of increased urinary incontinence in girls and women with cystic fibrosis.
- Trial name
- NCT00164138
- Testing
- Pelvic floor training group
- Where
- 2 sites in Australia
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Long COVID
Inspiratory Muscle Training in People With Long COVID-19- A Pilot Investigation.
This pilot investigation will recruit people with Long COVID to participate in a 4 week individualized inspiratory muscle training intervention with pre and post spirometry testing and additional functional outcomes to assess the…
- Trial name
- NCT06091358
- Testing
- PrO2
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Bath
COPD
QualiTy of Life Evaluation in Patients With ChRonic ObstructIve Pulmonary Disease Who Require Tiotropium as additiOnal treatmeNt.
Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous disease usually with a decline lung function and worsening symptoms; hence, both forced expiratory volume in 1 s (FEV1; lung function) and validated…
- Trial name
- TRITON (NCT06170125)
- Testing
- Tiotropium treated patients
- Volunteers
- 500 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Lung Carcinoma
Evaluating the Impact of Centralized Interventions on Lung Cancer Screening Adherence in Community Settings, ACCELL Trial
This clinical trial tests the impact of lung cancer screening care coordination interventions implemented at the system-level on lung cancer screening adherence in community settings.
- Trial name
- NCT06324110
- Testing
- Electronic Health Record Review, Interview, Patient Navigation
- Where
- United States
- Volunteers
- 6,772 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Childhood Obesity
Evaluation of an Online Lifestyle Intervention in Mexican School Children During COVID-19 Pandemic
Introduction: School closures due to the COVID-19 pandemic represent a risk factor for the development of childhood obesity due to the increase in unhealthy behaviors.
- Trial name
- NCT04772859
- Testing
- Online Lifestyle Intervention, Control Group
- Where
- Mexico
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Cystic Fibrosis
Prospective Intervention Study on Vitamin D in Patients With Cystic Fibrosis
The vast majority of Cystic Fibrosis (CF) patients worldwide are vitamin D insufficient. There is no evidence of benefit of vitamin D supplementation for CF patients yet.
- Trial name
- D-vitamin (NCT01321905)
- Testing
- Supplementation with vitamin D2/D3
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Karolinska Institutet
Oral Hygiene, Oral Health, Ventilators, Mechanical
Oral Care to Prevent Ventilator-associated Pneumonia
This study was conducted to investigate the effect of oral care given by two different methods on the development of ventilator-associated pneumonia in patients connected to mechanical ventilators.
- Trial name
- NCT05161962
- Testing
- One group received standard oral care., It was applied to the other group by aspiration.
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Ataturk University
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis)
Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS
This study evaluates potential of music therapy treatment to support breathing, speech, swallow and cough of persons with amyotrophic lateral sclerosis (ALS).
- Conditions
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis), Dysarthria, Flaccid, Dysarthria, Spastic
- Trial name
- NCT03604822
- Testing
- Music therapy
- Where
- 2 sites in Russia, United Kingdom
- Volunteers
- 8 people
- Sponsor
- Alisa Apreleva
Nutritional Support, Aerobic Exercise
Study on Pulmonary Rehabilitation for Stable Chronic Obstructive Pulmonary Disease(COPD) Patients
To compare the difference of effectiveness for stable COPD patients with poor nutritional status among three groups named health education, upper and lower limb exercises, and oral nutritional supplements.
- Conditions
- Nutritional Support, Aerobic Exercise, Respiratory Function Tests, Body Composition
- Trial name
- NCT04741373
- Testing
- oral nutritional supplements, rehabilitation exercise, health education
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Fudan University
Asthma
Tele-spirometry in Primary Care - Randomized Clinical Trial Cluster: the Effectiveness of Telemedicine in Asthma
The purpose of this study is to determine the effectiveness of telemedicine multifaceted intervention in symptoms patients with asthma.
- Trial name
- RESPIRANET-A (NCT02901522)
- Testing
- telemonitoring, Spirometry (baseline), Spirometry (20 - 22weeks)
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
ECMO Treatment, ARDS
Hemodynamic Monitoring and Fluid Responsiveness in Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) - "HemodynamECMOnitoring-VA Study"
In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels.
- Conditions
- ECMO Treatment, ARDS, Pneumonia, Intensive Care
- Trial name
- NCT06593756
- Testing
- Transthoracic Echocardiography, Uncalibrated Pulse Contour Analysis, Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Asthma
Developing and Implementing Asthma-Guidance and Prediction System (a-GPS) for Better Asthma Management
Asthma is the most common chronic condition in children and one of the five most burdensome diseases in the United States. Despite this, research and care for childhood asthma are limited by inefficient utilization of electronic…
- Trial name
- NCT02865967
- Testing
- Usual care + a-GPS, Usual care
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Mayo Clinic
Cystic Fibrosis (CF)
Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis
The goal of this clinical trial is to compare the effects of autogenic drainage and mechanical percussion on lung function, dyspnea, and quality of life in children with cystic fibrosis.
- Trial name
- ADMP-CF (NCT07729787)
- Testing
- Autogenic Drainage, Mechanical Percussion
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Lung Cancer
S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery
RATIONALE: A program that includes bupropion may be more effective in helping early-stage lung cancer patients to quit smoking. It is not yet known if a program to quit smoking is more effective with or without bupropion.
- Trial name
- NCT00032084
- Testing
- smoking cessation intervention, bupropion hydrochloride, nicotine
- Where
- 176 sites in United States, Puerto Rico
- Volunteers
- 10 people
- Sponsor
- SWOG Cancer Research Network
Neuromuscular Diseases
Methods to Improve Expiratory Cough Flow and Lung Volume in Children With NMDs
Children with neuromuscular diseases (NMDs) and weak chest muscles suffer frequent chest infections, hospital admissions and reduced life expectancy.
- Trial name
- NCT02342132
- Testing
- Non-invasive bipap ventilator, Mechanical insufflator-exsufflator, High frequency percussive oscillator
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
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