Clinical trials: Pulmonary Segmentectomy
Non-Small Cell Lung Cancer
Factors Determine the Feasibility and Surgical Margin Quality of Sublobar Resection for Non-small Cell Lung Cancer?
Sublobar resection (SR) has been recognized as non-inferior to lobectomy for small-sized non-small cell lung cancer (NSCLC). This study aimed to systematically identify the potential factors influencing the feasibility and…
- Trial name
- NCT07005401
- Where
- China
- Volunteers
- 1,064 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Pulmonary Nodule, Solitary
ICG Fluorescence Versus CO₂ Inflation-Deflation for Intersegmental Plane Identification During Thoracoscopic Segmentectomy
Intersegmental plane identification is a critical step in thoracoscopic anatomical segmentectomy because it helps ensure adequate surgical margins while preserving healthy lung tissue.
- Trial name
- NCT07745738
- Testing
- Indocyanine Green Fluorescence Imaging, Carbon Dioxide Inflation-Deflation
- Volunteers
- 50 people
- Sponsor
- Tongji Hospital
Non Small Cell Lung Cancer
Clinical Outcomes and Quality Of Life After Minimally Invasive Segmentectomy Versus Lobectomy for Lung Cancer
The goal is to compare patient reported outcomes, such as dyspnea, physical functioning and quality of life, between minimally invasive segmentectomy and lobectomy for stage I NSCLC during the first year after surgery.
- Trial name
- NCT07477158
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Lung Neoplasms, Pain
Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study
Whereas it, in the case of conventional thoracotomy, has been demonstrated that thoracic epidural analgesia is more effective than systemic opioids in terms of pain relief and preservation of postoperative pulmonary function, the…
- Conditions
- Lung Neoplasms, Pain, Immune Suppression
- Trial name
- SEAVATS (NCT02359175)
- Testing
- Bupivacaine in epidural catheter, Fentanyl in epidural catheter, Oral Paracetamol
- Where
- Denmark
- Volunteers
- 161 people
- Sponsor
- Odense University Hospital
Lung Cancer
A Study to Optimize Care for Lung Cancer Patients Undergoing Video-Assisted Thoracoscopic Surgery (VATS)
This is a research study for participants who have been diagnosed with lung cancer and are receiving VATS (Video Assisted Thoracoscopic Surgery) lobectomy or segmentectomy.
- Trial name
- NCT02502695
- Testing
- VATS-associated best practices
- Where
- 6 sites in United States
- Volunteers
- 173 people
- Sponsor
- Dana-Farber Cancer Institute
Lung Neoplasms, Surgery
Comparison of Segmentectomy Versus Lobectomy for Non-small Cell Lung Cancer ≤ 2 cm in the Middle Third of the Lung Field
This study aims to investigate whether segmentectomy had non-inferiority long-term oncological effects (disease-free survival and overall survival) compared with lobectomy in the treatment of patients with early-stage non-small…
- Trial name
- NCT04944563
- Testing
- Segmentectomy, Lobectomy
- Where
- China
- Volunteers
- 1,120 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Multiple Pulmonary Nodules
Fast Track Rehabilitation Following Video-assisted Lung Segmentectomy
Aim of this prospective randomized study is to assess the safety and efficacy of video-assisted lung segmentectomy (Group B) comparing with mini muscle-sparing thoracotomy (group A) during diagnostic process for pulmonary nodules.
- Trial name
- NCT01397045
- Testing
- VATS, Mini thoracotomy
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Theagenio Cancer Hospital
Non-Small Cell Lung Cancer
Septum-guided Segmentectomy for 2-3 cm Clinical Stage IA3 Peripheral Non-Small Cell Lung Cancer
This is a single-center, prospective, single-arm, open-label clinical trial evaluating the efficacy and safety of septum-guided segmentectomy in patients with 2-3 cm clinical stage IA3 peripheral non-small cell lung cancer…
- Trial name
- SGS2606 (NCT07780591)
- Testing
- septum-guided anatomical segmentectomy
- Volunteers
- 100 people
- Sponsor
- Shanghai Chest Hospital
Delirium, Aged
Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly Patients
The primary aim of this interventional study is to investigate the impact of perioperative administration of Maxigesic (combination of acetaminophen and ibuprofen) on delirium after minimally invasive lung surgery in elderly…
- Conditions
- Delirium, Aged, Lung Neoplasms, Robotic Surgical Procedures
- Trial name
- NCT05834569
- Testing
- Acetaminophen and Ibuprofen, Normal saline
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Korea University Guro Hospital
Pulmonary Surgical Procedures, Thoracic Surgery, Video-assisted
Registry of the Spanish Society of Thoracic Surgery
ReSECT is a project promoted by the Spanish Society of Thoracic Surgery with the aim not only to become an indefinite, dynamic and inclusive registry, but also to establish a common structural framework for the development of…
- Conditions
- Pulmonary Surgical Procedures, Thoracic Surgery, Video-assisted, Robotic Surgical Procedures, Thoracotomy
- Trial name
- ReSECT (NCT05600569)
- Where
- Spain
- Volunteers
- 30,000 people
- Sponsor
- Sociedad Española de Cirugía Torácica
Lung Cancer Stage I, Lung; Node
Intra-operative Air Leak Management After Minimally Invasive Lung Segmental Resection
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), a still unsolved issue is represented by intraoperative alveolar air leaks (IOAALs), which if prolonged beyond the…
- Conditions
- Lung Cancer Stage I, Lung; Node, Air Leak From Lung
- Trial name
- NCT06544200
- Testing
- Polymeric Hydrogel Matrix
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- University Hospital Padova
Thoracic Surgery
Contribution of 3D Printing in Anatomical Lung Segmentectomies.
The aim of the present work was to evaluate if the presence on the operating field of a 3D printed personalized model of the pulmonary anatomy of a patient operated by full thoracoscopy for an anatomical segmentectomy, makes it…
- Trial name
- 3DiLUNG (NCT05695404)
- Testing
- Segmentectomy
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Institut Mutualiste Montsouris
Non-small Cell Lung Cancer
Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer
Lungs are made up of individual lobes. When a lung cancer tumour is detected in one of these lobes, surgeons typically perform a Lobectomy.
- Trial name
- NCT02570815
- Testing
- indocyanine green
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Analgetic, Lung Cancer (NSCLC)
High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy
The aim is to conduct a randomized controlled trial (RCT) with a high dose arm (1mg/kg) vs a low dose (8mg in total) of steroid (Dexamethasone) given intravenous (IV) after the induction of anesthesia to "High-pain-responders" in…
- Conditions
- Analgetic, Lung Cancer (NSCLC), Video Assisted Thoracic Surgery (VATS), Glucocorticoid
- Trial name
- DEXTER (NCT07213375)
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
NSCLC, Stage I
Comparison of Sublobar and Lobectomy in Small (2 Cm or Less 0.5<CTR<1) Non-small Cell Lung Cancer: a Prospective, Multicenter Randomized Controlled Study
The early NSCLC（Non-small cell lung cancer） patients with partial solid nodules mainly composed of solid components, whose maximum tumor diameter was ≤ 2.0cm and 0.5<CTR（Consolidation tumor ratio）<1, as indicated by preoperative…
- Trial name
- NCT06028412
- Testing
- Sublobar, Lobectomy
- Where
- China
- Volunteers
- 660 people
- Sponsor
- Xiaolong Yan, Dr.
IA Lung Adenocarcinoma, Combined Segmentectomy
Combined Segmentectomy Versus Lobectomy for Stage IA Lung Adenocarcinoma With Ground-glass Component of Prospective, Randomized, Controlled Clinical Study
This project intends to include stage IA lung adenocarcinoma patients with CT imaging grboreal lesions; compare the results of lobectomy vs combined subsegmentectomy, and compare perioperative complications, differences in lung…
- Trial name
- NCT05983835
- Testing
- Patients receive subsegmentectomy
- Where
- China
- Volunteers
- 688 people
- Sponsor
- Fujian Medical University Union Hospital
Non-Small Cell Lung Cancer, Stage IA Non-Small Cell Lung Cancer
Segmentectomy Versus Lobectomy for Deep Solid-Dominant Early-Stage NSCLC
SOLID is a multicenter, open-label, randomized, controlled, phase III non-inferiority trial comparing anatomic segmentectomy with lobectomy in patients with deeply located, solid-dominant, clinical stage IA non-small cell lung…
- Trial name
- SOLID (NCT07698990)
- Testing
- Anatomic Segmentectomy, Anatomic Lobectomy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Chest Hospital
Non-small Cell Lung Cancer
Comparison of Lobectomy and Segmentectomy for cT1aN0M0 Peripheral NSCLC
Anatomic segmentectomy may be a less invasive type of surgery than lobectomy for cT1aN0M0 peripheral NSCLC and may retain more pulmonary function.
- Trial name
- NCT02481661
- Testing
- segmentectomy
- Where
- China
- Volunteers
- 610 people
- Sponsor
- Zhejiang Cancer Hospital
Lung Cancer
Disposable Powered Articulating Linear Cutter Stapler in Total-Thoracoscopic Anatomic Lobectomy (Segmentectomy)
To evaluate whether the anastomosis success rate of the main effectiveness evaluation indexes is not inferior to the similar products produced by Johnson \& Johnson when the Fengh Disposable Powered Articulating Endoscopic Linear…
- Trial name
- NCT05329402
- Testing
- Disposable Powered Articulating Endoscopic Linear Cutter Stapler, ECHELON Flex Powered Articulating Endoscopic Linear Cutters
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Fengh Medical Co., Ltd.
Lung Diseases, Surgery
Robotic Versus Video-assisted Lobectomy/Segmentectomy for Lung Surgery
To compare the safety/efficacy of the robotic-assisted lobectomy/segmentectomy (RAL/S) with the video-assisted lobectomy/segmentectomy (VAL/S) for lung resection.
- Trial name
- NCT05270616
- Testing
- robotic surgery, uniport surgery, multiple- port surgery
- Where
- China
- Volunteers
- 800 people
- Sponsor
- The Second Hospital of Shandong University