Clinical trials: Pulmonary Surgical Procedures
Low Cardiac Output
Hemodynamic Survey Cardiac Surgical Scenarios
The purpose of this study is to find out the Lidco Rapid ( monitoring tool gives cardiac output) is as equivalent in determining the hemodynamic assessment in cardiac surgical scenarios as the most often used pulmonary artery…
- Trial name
- NCT02529033
- Testing
- LIDCO Rapid, Pulmonary artery catheter
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Dyspnea, Pulmonary Edema
The Incidence of TRALI in Patients Undergoing Orthopedic-Oncology Surgery
Currently Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality in the United States, and one of major post-transfusion complications.
- Trial name
- NCT00914784
- Where
- Israel
- Volunteers
- 550 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Lung Cancer (Diagnosis)
Accurate Planning and Guidance of Bronchoscopy for Lung Cancer Management
The main objective of this project is to demonstrate the potential of three new technical innovations for improving state-of-the-art bronchoscopy guidance systems.
- Trial name
- NCT07822126
- Testing
- Virtual Navigation System
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Penn State University
Pancreatic Ductal Adenocarcinoma, Oligometastatic Disease
Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma
Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma (PHOLIPANC). This is an interventional, open-label, non-randomised, single-arm phase II clinical trial.
- Trial name
- NCT06122480
- Testing
- Surgery
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Non-Small Cell Lung Cancer (NSCLC)
A Study In Patients Who Will Undergo Surgical Removal Of Non-Small Cell Lung Cancer To Evaluate Molecular Changes That Occur In Tumor Tissue After Short Term Exposure To PF-00299804
This study will enroll patients who are planned to undergo surgical removal of their tumor. The goal of the study is to evaluate the changes that occur in the tumor after brief (about 8 days) exposure to the study drug.
- Trial name
- NCT00971191
- Testing
- PF-00299804
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Pfizer
Cholecystitis, Cholecystitis, Chronic
Shortwave Infrared Surgical Imaging Device Study
The goal of this observational study is to perform an in-human assessment of an investigational shortwave infrared (SWIR) imaging device, aimed to enhance the visualization of critical anatomical structures during surgical…
- Conditions
- Cholecystitis, Cholecystitis, Chronic, Chronic Calculous Cholecystitis, Primary Hyperparathyroidism
- Trial name
- NCT07744425
- Testing
- Observational study of SWIR imaging device in surgery
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cision Vision, Inc.
Coronary Artery Disease
Vascular Function on the First Day After Cardiac Surgery
This study examines the flow mediated dilation (FMD) of the brachial artery before and after cardiac surgery. FMD is measured with ultrasound technique.
- Trial name
- NCT02001090
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Norwegian University of Science and Technology
Lung Neoplasms
Chemotherapy Treatment in Re-occurring Non Small Cell Lung Cancer (NSCLC) After Previous Chemotherapy and Surgical Removal of the NSCLC Tumor
The purpose of this study is to help answer: Whether pemetrexed, gemcitabine and/or carboplatin can shrink tumor(s) or make tumor(s) disappear in patients with relapsed lung cancer (lung cancer that has come back after surgical…
- Trial name
- NCT00356525
- Testing
- pemetrexed, gemcitabine, carboplatin
- Where
- 17 sites in United States, Brazil and 1 more
- Volunteers
- 41 people
- Sponsor
- Eli Lilly and Company
Sepsis, Burn Injury
Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery.
- Conditions
- Sepsis, Burn Injury, Wound Healing, Critical Illness
- Trial name
- NCT07249762
- Testing
- Observational Cohort (No Intervention)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Lung Cancer
Combination Chemotherapy and Radiation Therapy Followed By Surgery in Treating Patients With Stage IIB or Stage IIIA Non-Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00006469
- Testing
- carboplatin, paclitaxel, conventional surgery
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Medstar Health Research Institute
Gastro-esophageal Cancer
PeRioperative Study of Exercise Training in Patients With Operable Cancer of the Gastroesophageal Junction
Background: For patients diagnosed with operable cancer of the gastro-esophageal junction (GEJ), the perioperative course of therapy is associated with severe deconditioning which includes weight loss and poor physical function…
- Trial name
- PRESET (NCT02722785)
- Testing
- Aerobic and Resistance Exercise Training
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Jesper Frank Christensen, PhD
Persistent Atrial Fibrillation
Study on the Ablation of Persistent Atrial Fibrillation Using Pulsed Electric Fields Under Different Surgical Procedures
Atrial fibrillation (AF) is one of the most common arrhythmias in clinical practice, and there are more than 20 million AF patients in my country.
- Trial name
- NCT06671197
- Testing
- Pulmonary vein isolation, Pulmonary vein isolation+posterior left atrial wall line+superior vena cava isolation
- Where
- China
- Volunteers
- 436 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Non-small Cell Lung Cancer
Follow-up of Patients With Curative-intent Surgical Resection for NSCLC
The guidelines and institutional practices recommended more frequent visits the two years following curative-intent therapy for non-small cell lung cancer (NSCLC).No international consensus is published concerning follow-up of…
- Trial name
- NCT00199615
- Testing
- PET
- Where
- France
- Volunteers
- 73 people
- Sponsor
- University Hospital, Limoges
Paroxysmal Atrial Fibrillation, Coronary Artery Disease
Surgical Pulmonary Vein Isolation Efficiency Study
A substantial proportion of patients undergoing elective coronary artery bypass grafting have a history of paroxysmal atrial fibrillation. Paroxysmal atrial fibrillation has adverse short-and long term postoperative effects.
- Trial name
- FIN-PVI (NCT01791218)
- Testing
- CABG, AVR or CABG+AVR and PVI, CABG, AVR or CABG+AVR
- Where
- Finland
- Volunteers
- 2 people
- Sponsor
- Kuopio University Hospital
Breast Cancer, Colorectal Cancer
Prospective Collection of Surplus Surgical Tumor Tissues and Pre-surgical Blood Samples
The study is intended to collect specimens to support the application of genome analysis technologies, including large-scale genome sequencing.
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- GBCPRT0008 (NCT01792882)
- Where
- United States
- Sponsor
- Global BioClinical
Neuropathic Pain, Post Operative Pain
Post-Operative Pain After Recovery in Thoracic Surgery
Persistent pain after surgery has significant physical and mental consequences for the patient, as well as a significant economic impact on health systems.
- Conditions
- Neuropathic Pain, Post Operative Pain, Thoracic Surgery
- Trial name
- POPARTS (NCT04300660)
- Testing
- neuropathic pain after thoracic surgery
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- University of Trieste
Lung Cancer
A Prehabilitation Program to Boost Postoperative Functional Capacity in Surgical Lung Cancer Patients
This research study is evaluating a prehabiliation intervention designed to improve postoperative functional capacity (measured by 6-minure walking distance) in individuals undergoing lung resection for cancer.
- Trial name
- NCT04826835
- Testing
- Prehabilitation intervention, Health education control
- Where
- Hong Kong
- Volunteers
- 198 people
- Sponsor
- The University of Hong Kong
Atrial Fibrillation
SOLAR & ATRILAZE Atrial Fibrillation Trial
The purpose of study is to conduct a pivotal evaluation of the EndoPhotonix™ SOLAR™ System and ATRILAZE™ System in order to obtain a labeling claim on the devices for the treatment of atrial fibrillation.
- Trial name
- SAAF-T (NCT00734058)
- Testing
- Laser MAZE by Ablation of Cardiac Tissue
- Volunteers
- 90 people
- Sponsor
- EndoPhotonix, Inc.
Postoperative Complications, Procedure, Thoracic Surgical
Preoperative RESpiratory Training and MOBilization to Prevent Postoperative Pulmonary Complications in Patients Undergoing Thoracic Surgery
Postoperative pulmonary complications (PPCs) are the most frequent complications occurring in patients undergoing thoracic surgery and they are associated with prolonged hospital stay, decreased survival and expanding medical…
- Trial name
- RESMOB (NCT05416411)
- Testing
- Inspiratory muscle training
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 436 people
- Sponsor
- Istanbul University
Lung Cancer
Surgical Positioning of the Arm During Thoracic Surgery -Effect on Shoulder Pain After Surgery?
Up to 85% experience shoulder pain after thoracic surgery, especially on the same side as surgery are performed. Referred phrenic nerve pain is probably one cause of ipsilateral shoulder pain (ISP), and positioning of the arm…
- Trial name
- NCT02149849
- Testing
- Modified lateral positioning.
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Oslo University Hospital