Clinical trials: Pulmonary Ventilation Function
Covid19, Dyspnea
Understanding Exertional Dyspnea and Exercise Intolerance in COVID-19
A novel corona virus emerged in 2019 causing Corona Virus Disease 2019 (covid-19). In one year more than 80 000 000 cases worldwide were documented.
- Trial name
- NCT04732663
- Testing
- No Intervention
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Pain, Hypoxia
Effects of Static Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function
The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent static apneas training session at high lung volume in healthy subjects; also, as secondary objectives, to analyze…
- Conditions
- Pain, Hypoxia, Hypercapnia, Apnea
- Trial name
- NCT06150677
- Testing
- Voluntary apnoea
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Mechanical Ventilation Complication, Postoperative Pulmonary Atelectasis
Flow Controlled Ventilation in Robot-assisted Laparoscopic Surgery
The optimization of ventilation is especially important during general anaesthesia, when active, physiologic respiration suspends and is replaced by non-physiologic mechanical positive pressure ventilation.
- Trial name
- FCV-IMPALA (NCT06256900)
- Testing
- Flow-controlled ventilation, Pressure-controlled ventilation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Pulmonary Disease
Effect of Glossopharyngeal Versus Diaphragmatic Breathing Exercise on Pulmonary Function After Decortication Surgery
This study will be conducted to compare between the effect of glossopharyngeal and diaphragmatic breathing exercises on pulmonary functions after decortication surgery
- Trial name
- NCT06518759
- Testing
- traditional chest techniques, Glossopharyngeal breathing exercise, Diaphragmatic breathing exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Asthma, Obesity
Study of the Physiology of the Asthma of the Obese Subjects. Breathing Obesity Asthma Study (BOA)
Asthma is more frequent in obese women, but the mechanisms underlying the causes of this increased frequency are unknown and are different from usual asthma pathophysiology (associated with allergy).
- Trial name
- BOA (NCT00577733)
- Where
- France
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post COVID-19
Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults
When the literature search is conducted, it is seen that there are many studies examining the effects of COVID-19 disease on individuals in various disease groups (MS, stroke, Parkinson, COPD, asthma, etc.) and age groups (adult…
- Trial name
- PEPICov (NCT05282043)
- Testing
- Evaluation of Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Aerosol Disease, Covid19
A Safety Assessment of the iZephyr Hood for NIV in COVID-19 Patients
This study is a safety assessment of the iZephyr hood a novel aerosol removal device in patients receiving non invasive ventilation for COVID-19.
- Conditions
- Aerosol Disease, Covid19, Noninvasive Ventilation
- Trial name
- iZephyr (NCT04904484)
- Testing
- iZephyr hood
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Respiratory Compliance, Functional Residual Capacity
Rescue Antenatal Steroids and Pulmonary Function Tests in Preterm Infants
One course of steroids given to a mother before a premature delivery helps the lungs of the premature infant and decreases breathing problems.
- Conditions
- Respiratory Compliance, Functional Residual Capacity, Pulmonary Function Testing
- Trial name
- NCT00669383
- Testing
- betamethasone
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Postoperative Pulmonary Dysfunction, Oxygenation Impairment
Mechanical Power Ventilation in RALP
Robot-assisted laparoscopic radical prostatectomy (RALP) requires steep Trendelenburg positioning and pneumoperitoneum, which adversely affect respiratory mechanics and may lead to impaired postoperative oxygenation.
- Conditions
- Postoperative Pulmonary Dysfunction, Oxygenation Impairment, Robot-Assisted Radical Prostatectomy
- Trial name
- NCT07534553
- Testing
- Mechanical Power-Targeted Ventilation, Standard Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pain, Hypoxia
Effects of Static Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function
The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent static apneas training session at low lung volume in healthy subjects; also, as secondary objectives, to analyze…
- Conditions
- Pain, Hypoxia, Hypercapnia, Apnea
- Trial name
- NCT06158256
- Testing
- Voluntary apnoea
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Lung Collapse, One-Lung Ventilation
Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms
Lung isolation technique and one-lung ventilation (OLV) are the mainstays of thoracic anesthesia. Two principal lung isolation techniques are mainly use by clinicians, the double lumen tubes (DLT) and the bronchial blockers (BB).
- Conditions
- Lung Collapse, One-Lung Ventilation, Thoracic Surgery, Video-Assisted
- Trial name
- PLC-OLV (NCT02919267)
- Testing
- Double lumen tube, Bronchial blocker
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laval University
Cystic Fibrosis, Chronic Obstructive Pulmonary Disease (COPD)
Prevalence and Treatment of Urinary Incontinence in Women With Cystic Fibrosis and Chronic Obstructive Pulmonary Disease
Women with chronic lung disease characterised by chronic cough report urinary incontinence. Recently there have been reports of increased urinary incontinence in girls and women with cystic fibrosis.
- Trial name
- NCT00164138
- Testing
- Pelvic floor training group
- Where
- 2 sites in Australia
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Brachial Plexus Block, Pulmonary Ventilation
Ventilation and Pulmonary Aeration, Electrical Impedance Tomography, Interscalene Brachial Plexus Block
Patients with indication of shoulder surgery will be submitted to ultrasound-guided interscalene brachial plexus block with 4ml or 15ml of bupivacaine- epinephrine 0,5%- 1:200,000 at level of C5-6 roots and will be evaluated…
- Trial name
- NCT03577860
- Testing
- Bupivacaine 4 mL, Bupivacaine 15 mL
- Where
- 2 sites in Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Normal Subjects
Radioaerossol Pulmonary Deposition Using Mesh in Normal Subjects
In vivo deposition studies of aerosol administration during noninvasive ventilation are scarce in the current literature. We assessed 10 normal subjects in a crossover study evaluated by pulmonary scintigraphy aiming to compare…
- Trial name
- NCT01889524
- Testing
- Mesh nebulizer, Jet nebulizer, Noninvasive ventilation-NIV
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Cystic Fibrosis in Children
19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease
This study capitalizes on the emerging technology of 19F MRI, using conventional 'thermally' polarized perfluorinated gas (perfluoropropane, or PFP) mixed with oxygen and studied with magnetic resonance imaging (MRI) to visualize…
- Trial name
- NCT06066723
- Testing
- 19F MRI
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infant, Newborn, Infant, Low Birth Weight
Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia
This study tested whether Neonatal Intensive Care Unit (NICU) teams trained in benchmarking -- comparing care practices between different NICUs to see which practices prevent bronchopulmonary dysplasia (BPD) -- and quality…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- Benchmarking (NCT00067613)
- Testing
- Benchmarking Management Practices, Standard Management Practices
- Where
- 17 sites in United States
- Volunteers
- 4,095 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Lower Urinary Tract Disorder
Pelvic Floor Muscle Activity, Respiratory Functions, Respiratory Muscle Strength, and Functional Capacity in Children With Lower Urinary Tract Dysfunction
The functional disorders of the lower urinary tract in children involve overactive bladder with thickening of the bladder muscle, resulting in a decrease in functional bladder volume and an increase in intra-bladder pressure.
- Trial name
- NCT06652178
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Blood Pressure, HDL Low
Effects of a 10 Component Dietary Supplement on Health and the Quality of Life
This open-label field trial evaluates the effects of treatment with a multi-pathway dietary supplement (Stem Cell 100+) that has been commercially available for several years.
- Conditions
- Blood Pressure, HDL Low, Stress, Lung Function Decreased
- Trial name
- NCT03052491
- Testing
- Stem Cell 100+
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centagen, Inc.
Cardiogenic Pulmonary Edema
Helmet CPAP Versus HFNC in Acute Cardiogenic Pulmonary Edema
This study objectively held to compare the physiological outcomes in the non-invasive (NIV) treatment of Acute Cardiogenic Pulmonary Oedema (ACPE) patients in the Emergency Department (ED) delivered by Helmet CPAP (hCPAP) and…
- Trial name
- HCPAPvsHFNC (NCT04005092)
- Testing
- hCPAP versus HFNC
- Where
- Malaysia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Hospital Raja Permaisuri Bainun
Pain, Hypoxia
Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function
The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent walking apneas training session at low lung volume in healthy subjects; also, as secondary objectives, to analyze…
- Conditions
- Pain, Hypoxia, Hypercapnia, Apnea
- Trial name
- NCT06158295
- Testing
- Voluntary apnoea
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle