Clinical trials: Pulmonary and Extra- Pulmonary Tuberculosis (TB)
Tuberculosis, Tuberculosis, Pulmonary
Shortened Regimen for Drug-susceptible TB in Children
While drug-susceptible tuberculosis (TB) disease in children currently requires four to six months of treatment, most children may be able to be cured with a shorter treatment of more powerful drugs.
- Conditions
- Tuberculosis, Tuberculosis, Pulmonary, Tuberculosis, Lymph Node, Mycobacterium Tuberculosis
- Trial name
- SMILE-TB (NCT06253715)
- Testing
- Isoniazid, Rifampin, Pyrazinamide
- Where
- 9 sites in India, Indonesia and 5 more
- Volunteers
- 860 people
- Sponsor
- Johns Hopkins University
Tuberculosis
Effect of Xpert MTB/RIF on Patient Outcomes
A parallel-group prospective cohort study among adult persons living with HIV/AIDS to study the effect of a new TB diagnostic test, Xpert MTB/RIF on: 1) TB case detection; 2) time to TB diagnosis and TB treatment; 3) presumptive…
- Trial name
- NCT02729532
- Testing
- Xpert
- Where
- Zambia
- Volunteers
- 776 people
- Sponsor
- University of North Carolina, Chapel Hill
Tuberculosis, Pulmonary, Tuberculosis, Extrapulmonary
Clinical Evaluation of the NanoDetect-TB Mycobacterium Tuberculosis Detection Kit for the Diagnosis of Tuberculosis Disease
The goal of this observational study is investigate the accuracy of the NanoDetect-TB kit in diagnosing tuberculosis (TB) using frozen serum and plasma samples collected from individuals suspected to have TB disease.
- Conditions
- Tuberculosis, Pulmonary, Tuberculosis, Extrapulmonary, Tuberculosis Active
- Trial name
- NCT05981495
- Testing
- NanoDetect-TB
- Volunteers
- 460 people
- Sponsor
- NanoPin Technologies, Inc.
Extrapulmonary Tuberculosis, Tuberculosis, Pulmonary
POC Strategies to Improve TB Care in Advanced HIV Disease
Tuberculosis (TB) remains the major cause of morbidity and mortality among patients with HIV. Sub-optimal diagnostics contributes towards poor patient outcome and there is an urgent need to identify non-sputum-based point-of-care…
- Conditions
- Extrapulmonary Tuberculosis, Tuberculosis, Pulmonary, Human Immunodeficiency Virus (HIV), Acquired Immunodeficiency Syndrome
- Trial name
- TBPOC (NCT04122404)
- Testing
- LF-LAM
- Where
- 3 sites in Ghana
- Volunteers
- 425 people
- Sponsor
- University of Southern Denmark
Pulmonary and Extra- Pulmonary Tuberculosis (TB)
Study About Drug Resistance of Mycobacterium Tuberculosis
Tuberculosis is a major cause of ill health and one of the leading causes of death worldwide. Early, rapid and accurate diagnosis of all TB patients and prompt treatment with any form of drug-susceptible or drug resistant TB is…
- Trial name
- NCT07169149
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Sohag University
Tuberculosis
Enhanced TB Screening to Determine the Prevalence and Incidence of TB in Patients With HIV
This study will examine an enhanced protocol to systematically screen a cohort of 400 new HIV clinic enrollees for prevalence and 1-year incidence of tuberculosis (TB).
- Trial name
- NCT02043067
- Testing
- Comprehensive TB screening
- Where
- Zambia
- Volunteers
- 400 people
- Sponsor
- University of North Carolina, Chapel Hill