Clinical trials: Pulp Exposure, Dental
Vital Pulp Therapy
Diagnostic Biomarkers to Correlate Molecular Changes and Inflammatory Cascade in the Dental Pulp.
This study aimed to evaluate the molecular changes that occur within the pulp tissue during inflammation and its correlation with vital pulp therapy with its different treatment modalities (Direct pulp capping, Partial Pulpotomy…
- Trial name
- NCT05464797
- Testing
- Pulp therapy, Cytokines level in pulpal blood.
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries, Pulp Disease, Dental
Pulpotomy Versus Pulpectomy in Vital Primary Incisors
The aim of this split mouth randomized controlled study was to compare formocresol pulpotomy and zinc-oxide and eugenol pulpectomy in the treatment of vital pulp exposure in primary incisor.
- Trial name
- NCT05589025
- Testing
- pulpotomy technique with formocresol, pulpectomy technique with zinc oxide and eugenol
- Volunteers
- 39 people
- Sponsor
- National Research Centre, Egypt
Dental Pulp Exposure
Comparative Evaluation of Clinical and Radiographic Outcomes of Mustard Gel (Brassica Nigra) and Mineral Trioxide Aggregate (MTA) as Pulpotomy Agents in Deciduous Molars- A Randomized Controlled Trial
The aim of this clinical trial is to compare two materials to treat baby molars with deep cavities. When the cavity is very deep and reaches the nerve of a baby tooth, dentist perform a treatment called "Pulpotomy".
- Trial name
- MG-MTA-RCT2026 (NCT07557290)
- Testing
- Intervention 1: Mustard Gel, Intervention 2 : Mineral Trioxide Aggregate (MTA)
- Volunteers
- 72 people
- Sponsor
- Dr Nida Farooq
Dental Caries, Dental Pulp Exposure
MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial
To compare radiographic and clinical outcomes and survival of mineral trioxide aggregate/ferric sulfate (MTA/FS) pulpotomy and root canal therapy (RCT) in carious vital primary maxillary incisors.
- Trial name
- MTA/FS (NCT02019563)
- Testing
- RCT Group, MTA/FS pulpotomy Group
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- The Hospital for Sick Children
Dental Caries, Pulp Exposure, Dental
Comparative Clinical and Radiographic Evaluation of Different Pulpotomy Materials in Primary Molars
This randomized clinical trial compared the clinical and radiographic outcomes of ferric sulfate (FS), mineral trioxide aggregate (MTA), calcium-enriched mixture (CEM), and TheraCal PT used for pulpotomy in primary molars.
- Conditions
- Dental Caries, Pulp Exposure, Dental, Primary Teeth, Primary Molar Pulpotomy
- Trial name
- NCT07769697
- Testing
- Pulpotomy, Mineral Trioxide Aggregate (MTA), Calcium-Enriched Mixture (CEM)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Inonu University
Dental Pulp Exposure
Histological Evaluation of Hard Tissue Formation After Direct Pulp Capping With RetroMTA
This study presents a clinical and histological evaluation of human pulp tissue responses after direct capping using RetroMTA. Seven teeth were subjected to pulp exposure, direct capping with RetroMTA, and restoration with a…
- Trial name
- RetroMTA (NCT03631511)
- Testing
- direct pulp capping with RetroMTA
- Where
- Poland
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Reversible Pulpitis, Dental Pulp Exposure
Direct Pulp Capping With Biodentine in Permanent Teeth With Reversible Pulpitis
This study evaluates the clinical and radiographic outcomes of direct pulp capping using Biodentine (Septodont, Saint-Maur-des-Fossés, France), a calcium silicate-based cement, in mature permanent teeth diagnosed with reversible…
- Trial name
- NCT07834424
- Testing
- Direct pulp capping with Biodentine
- Where
- Vietnam
- Volunteers
- 12 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Dental Pulp Exposure
Pulp Capping With Two Different Agents
The purpose of this study is to determine if MTA or calcium hydroxide are more effective as pulp capping agents
- Trial name
- MTA (NCT00812877)
- Testing
- Mineral Trioxide Aggregate, Calcium Hydroxide
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Reversible Pulpitis
TheraCal PT vs. Formocresol in Primary Molar Pulpotomies
This prospective, randomized, parallel-group clinical trial evaluated the 12-month clinical and radiographic success rates of TheraCal PT versus formocresol in primary molar vital pulpotomies among 50 children aged 5 to 8 years.
- Trial name
- NCT07864181
- Testing
- Dual cured resin modified
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Hama University
Pulp Exposure, Dental
Retrospective Evaluation of the Results of Direct Pulp Capping Treatment
The aim of this retrospective study is to evaluate the vitality of teeth that had been treated with calcium hydroxide in direct pulp capping cases.
- Trial name
- NCT05397964
- Testing
- Radiopaque Calcium Hydroxide Composition
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Molar Hypomineralization
Pulpotomy in Hypominerlized Permanent Molars.
The first permanent molars in children can sometimes develop a condition called molar-incisor hypomineralization (MIH), which affects the strength and quality of the tooth structure.
- Trial name
- NCT07756216
- Testing
- Step wise pulpotomy
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
Dental Pulp Exposure
The Effect of Laser Combined With Pulp-capping Agents on Direct Pulp Capping
The purpose of this randomized clinical study was to evaluate the efficiency of Er,Cr:YSGG laser irradiation combined with a resin based tricalcium silicate material and calcium hydroxide (CH) in direct pulp capping for 3 months…
- Trial name
- NCT02487329
- Testing
- Calcium Hydroxide, Er,Cr:YSGG laser + calcium hydroxide, TheraCal LC
- Volunteers
- 60 people
- Sponsor
- Near East University, Turkey
Pulpitis Reversible, Pulp Exposure, Dental
Comparative Evaluation of Eggshell Powder in Primary Teeth Pulpotomy
To assess \& compare clinical \& radiographic effects of Eggshell Powder, Biodentine and MTA as pulpotomy agents in primary teeth.
- Trial name
- NCT05812053
- Testing
- pulpotomy, cone beam computed tomography (CBCT) assessment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Dental Pulp Exposure
The CAP-2 Trial: Effect of Direct Pulp Capping Versus Partial Pulpotomy
CAP-2 Trial Background: This trial is being done in conjunction with an ongoing clinical trial investigating stepwise excavation versus final excavation on deep caries lesions (The CAP-1 trial).
- Trial name
- NCT00187850
- Testing
- PP, DPC
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Copenhagen
Apexogenesis, Pulp Exposure, Dental
Bioceramic Repair Materials in Apexogenesis of Immature Permanent Molars
The present study was conducted to compare the clinical, radiographic, and tomographic outcomes of apexogenesis using Bio-C Repair and Biofactor MTA in immature permanent first molars with vital asymptomatic pulp exposure.
- Conditions
- Apexogenesis, Pulp Exposure, Dental, MTA Vital Tooth Pulpotomy, Cone Beam Computed Tomography
- Trial name
- NCT07883239
- Testing
- Bioceramic Repair Pulpotomy (BIO-C® REPAIR), Mineral Trioxide Aggregate Pulpotomy (Biofactor MTA)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Postoperative Pain, Endodontically Treated Teeth
Postoperative Pain After Dental Post Application
In this study the effect of dental post application on postoperative dental pain in patients with asymptomatic teeth after a single-appointment root canal treatment will be evaluated.
- Conditions
- Postoperative Pain, Endodontically Treated Teeth, Vibration; Exposure
- Trial name
- NCT03942107
- Testing
- Group 1: single-visit RCT, Group 2: two-visit RCT
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Dental Caries Extending Into Dentin
Comparison of Conventional Versus Conservative Caries Removal in Primary Teeth
The sample will be, at least, 90 primary molars, randomly distributed into three groups: Group 1: IPC; Group 2: SE; Group 3: SCR.
- Trial name
- Caries_removal (NCT03650647)
- Testing
- Carious dentin removal
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Pulp Exposure, Postoperative Pain
Diode Laser-Assisted Direct Pulp Capping Trial
This randomized controlled clinical trial evaluates whether adjunctive 808-nm diode laser therapy after direct pulp capping reduces postoperative pain and dentin hypersensitivity compared with conventional Biodentine treatment.
- Conditions
- Dental Pulp Exposure, Postoperative Pain, Dentin Hypersensitivity
- Trial name
- NCT07593508
- Testing
- Biodentine, 808-nm Diode Laser
- Where
- Vietnam
- Volunteers
- 56 people
- Sponsor
- Hue University of Medicine and Pharmacy
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici