Clinical trials: Pulpitis, open to volunteers
Post Operative Pain
Assessment of Post-Operative Pain After Using Cryotherapy and Dexamethasone
Evaluation and comparing the effect of cryotherapy and dexamethasone on inflammatory mediators and post-operative pain in symptomatic irreversible pulpitis with acute apical periodontitis.
- Trial name
- NCT07738302
- Testing
- cold NaOCl , dexamethasone, NaOCl, dexamethasone, cold NaOCl and cold saline
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Postoperative Pain, Flare up
Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence
This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical…
- Conditions
- Postoperative Pain, Flare up, Flare Up, Symptom
- Trial name
- NCT07084194
- Testing
- Chitosan Nanoparticles Irrigant, aloe vera nanoparticles irrigant, Diode Laser Activation
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Minia University
Symptomatic Irreversible Pulpitis (SIP)
Regenerative Potentials of Mature Mandibular Molars With Symptomatic Irreversible Pulpitis Enhanced With Different Scaffolds
The current study aims to assess the influence of different scaffolds on postoperative pain and success rate of pulpotomy in mandibular mature molars with symptomatic irreversible pulpitis
- Trial name
- NCT07196683
- Testing
- Regenerative pulpotomy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Pulpitis - Irreversible
Outcome of Pulpotomy With MTA and Biodentin in Permanent Teeth With Caries Exposure
The success of pulpotomy treatment is affected by the type of biologically active material used.The effects of MTA and biodentine are compared in mature permanent teeth with caries exposure.It is expected that pulpotomy using…
- Trial name
- NCT06913283
- Testing
- Pulp Therapy with Mineral trioxide aggregate (MTA), Pulp Therapy with Biodentine
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Altamash Institute of Dental Medicine
Pulpitis - Irreversible
Clinical and Radiographic Success of Pulpotomy Using Neoputty Mineral Trioxide Aggregate Versus Pulpectomy Using Endoflas In Primary Molars With Irreversible Pulpitis: A Randomized Controlled Trial
The goal of this randomized clinical trial is to evaluate the clinical and radiographic success of pulpotomy using Neoputty MTA vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06922578
- Testing
- NeoPUTTY MTA pulpotomy, Endoflas pulpectomy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis and Post Operative Pain
Laser-Assisted vs Conventional Total Pulpotomy in Symptomatic Irreversible Pulpitis
his randomized controlled clinical trial will compare laser-assisted total pulpotomy with conventional total pulpotomy in permanent molar teeth diagnosed with symptomatic irreversible pulpitis.
- Trial name
- LASERPULP (NCT07850258)
- Testing
- Conventional Total Pulpotomy, Laser-Assisted Total Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- meliksahgunduz
Post-operative Pain, Pulpitis - Irreversible
Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis
The aim of this study is to evaluate the clinical effectiveness of total pulpotomy (TP), radicular pulpotomy (RP), and root canal treatment (RCT) in mandibular premolar and/or molar teeth diagnosed with symptomatic irreversible…
- Conditions
- Post-operative Pain, Pulpitis - Irreversible, Success Rate
- Trial name
- NCT07375576
- Testing
- Total Pulpotomy, Radicular pulpotomy, Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Root Canal Infection
Postoperative Pain After Using a Minimally Invasive Reciprocating Single-file System in Mandibular Molars With Symptomatic Irreversible Pulpitis
The aim of the present study is to assess the incidence and severity of postoperative pain after root canal preparation of mandibular molars with symptomatic irreversible pulpitis using a minimally invasive reciprocating…
- Trial name
- NCT07718607
- Testing
- Reciprocating rotary single-file system, Wave One Gold rotary file system
- Volunteers
- 56 people
- Sponsor
- Minia University
Symptomatic Irreversible Pulpitis
Preoperative Dexamethasone Injection to Improve Local Anesthesia Success in Endodontic Treatment
This study aims to determine whether giving a single dose of 4mg dexamethasone before root canal treatment can reduce the amount of pain patients experience during the procedure .
- Trial name
- DILAS (NCT07699315)
- Testing
- dexamethasone, Saline (0.9% NaCl)
- Volunteers
- 60 people
- Sponsor
- Watim Medical & Dental College
Pulpitis - Irreversible, Ozone
Zinc Oxide Ozonated Olive Oil in LSTR
This study will be carried out to evaluate and compare the clinical and radiographic effect of zinc oxide-ozonated olive oil (ZnO-OO) versus Modified Triple Antibiotic Paste (MTAP) as a Lesion Sterilization and Tissue Repair…
- Conditions
- Pulpitis - Irreversible, Ozone, Pulp Disease, Dental, Primary Teeth
- Trial name
- Zn-OO/MTAP (NCT06854744)
- Testing
- lesion sterlization and tissue repair, Zinc Oxide Ozonated Oil, Modified Triple Antibiotic Paste
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Postoperative Pain
Effect of Passive Ultrasonic Irrigation Activation Cycle on Postoperative Pain
One of the most important goals of root canal treatment is to eliminate bacteria from infected canals. However, conventional irrigation methods combined with mechanical preparation applied during root canal treatment may not be…
- Trial name
- NCT06711029
- Testing
- Conventional needle irrigation, Passive Ultrasonic Irrigation with 3*20 sn, Passive Ultrasonic Irrigation with 6*10 sn
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Esin Özlek
Endodontic Inflammation
Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth.
- Trial name
- NCT07779148
- Testing
- Xp Finisher R file
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Minia University
Irreversible Pulpitis
Post Operative Pain Following Pulpectomy Versus Pulpotomy in Primary Molars Wit Irreversible Pulpitis
Study will evaluate and compare post operative pain for primary molars with irreversible pulpitis after pulpotomy and pulpuectomy
- Trial name
- NCT06903013
- Testing
- Non vitalPulp therapy, Vital pulp therapy
- Volunteers
- 50 people
- Sponsor
- Minia University
Carious Primary Molars
Pulpotomy With CEM vs Pulpectomy With Ca(OH)2/Iodoform in Primary Molars
Will Calcium-Enriched Mixture (CEM) cement pulpotomy have less postoperative pain and more clinical and radiographic success compared to Calcium Hydroxide/Iodoform (Metapex) pulpectomy when managing second primary molars with…
- Trial name
- NCT07265063
- Testing
- Pulpotomy using Calcium-Enriched Mixture (CEM) Cement, Pulpectomy using Calcium Hydroxide/Iodoform Paste (Metapex)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Comparative Evaluation of Post Obturation Pain After Root Canal Treatment Using Tricalcium Silicate vs Resin-Based Sealers
This is a randomized controlled trial comparing the mean and standard deviation of postobturation pain using two different sealers: a tricalcium silicate-based sealer (CeraSeal) and a resin-based sealer (Endoplus) in patients…
- Trial name
- NCT07388368
- Testing
- Tricalcium silicate sealar, Resin based sealer
- Where
- Pakistan
- Volunteers
- 118 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Pulp Disease, Dental, Pulp Therapy in Primary Molars
Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary Molars
This study aims to evaluate clinical and radiographic success of oxymetazoline versus sodium hypochlorite as hemostatic agents in MTA pulpotomy of primary molars.
- Conditions
- Pulp Disease, Dental, Pulp Therapy in Primary Molars, Pulpitis - Reversible, Pulp Inflammation
- Trial name
- OXY - MTA (NCT07675330)
- Testing
- Oxymetazoline 0.05% nasal solution, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Reversible Pulpitis, Deep Caries
Comparative Evaluation of Direct Pulp Capping Between Deep and Extremely Deep Caries in Mature Permanent Mandibular Molars .
The aim of the study is to compare the clinical and radiographic outcomes of direct pulp capping for deep and extremely deep caries in mature permanent mandibular molars with reversible pulpitis.
- Conditions
- Reversible Pulpitis, Deep Caries, Extremely Deep Caries
- Trial name
- NCT07696702
- Testing
- Direct pulp capping in extremely deep carious lesion., Direct pulp capping in deep carious lesion.
- Where
- India
- Volunteers
- 130 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Dental Pulp Necrosis, Pulpitis
Metagenomic Analysis and Postoperative Pain in Infected Root Canals Using Different Irrigation Protocols
Achieving effective root canal disinfection while minimizing postoperative pain is a critical goal in endodontic therapy. Advanced irrigation protocols, such as ultrasonic activation, laser activation, negative pressure…
- Trial name
- NCT07546773
- Testing
- Ultrasonic Irrigation Activation, Laser-Activated Irrigation, Mechanical Irrigation Activation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Irriversible Pulpitis, Irrigation
Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods
root canal irrigation protocol
- Conditions
- Irriversible Pulpitis, Irrigation, Activation, Patient
- Trial name
- NCT07196215
- Testing
- passive ultrasonic activation, sonic activation
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- RANA AHMAD
Periapical Periodontitis, Pulpitis
Postoperative Pain Evaluation After Obturation With Different Sealers
This study aims to evaluate the incidence and intensity of postoperative pain in patients undergoing root canal treatment on teeth diagnosed with pulpitis, pulp necrosis, or with previous endodontic treatment.
- Conditions
- Periapical Periodontitis, Pulpitis, Necorsis
- Trial name
- NCT07018284
- Testing
- AH Plus (Dentsply Sirona, Charlotte, NC, USA), NeoSealer Flo, Continuous Wave Condensation
- Where
- Spain
- Volunteers
- 270 people
- Sponsor
- University of Siena