Clinical trials: Pulse Pressure Variation
Patients Receiving Protective Lung Ventilation, Patients in Grey Zone (3 < Pulse Pressure Variation (PPV) < 17
A Functional Test to Assess Fluid Status During Lung Protective Ventilation Strategies
Dynamic preload indices, such as pulse pressure variation (PPV) and stroke volume variation (SVV) are generally accepted as accurate indicator of fluid responsiveness in mechanically ventilated patients.
- Trial name
- NCT04118244
- Testing
- lung recruitment maneuver
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Hemodynamic Instability, Hypovolemia
Comparison of PPV and LVOT VTI During Passive Leg Raising to Predict Fluid Responsiveness
Hemodynamic instability remains one of the leading causes of morbidity and mortality among critically ill patients in intensive care units. One major contributor to this instability is intravascular fluid deficit.
- Conditions
- Hemodynamic Instability, Hypovolemia, Critical Illness, Pulse Pressure Variation
- Trial name
- NCT07304661
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Izmir Katip Celebi University
Brain Tumor Adult, Pulse Pressure Variation
Pulse Pressure Variation vs. Central Venous Pressure for Fluid Management in Intracranial Tumor Surgery
This study investigates the efficacy of pulse pressure variation (PPV) compared to central venous pressure (CVP) in guiding fluid management during intracranial tumor surgeries.
- Conditions
- Brain Tumor Adult, Pulse Pressure Variation, Central Venous Pressure, Fluid Management
- Trial name
- PPV-CVP-FLUID (NCT06776666)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
Pulse Pressure Variation, Stroke Volume Variation
Peripheral Venous Pressure Variation, Pulse Pressure Variation and Pleth Variability Index for Fluid Responsiveness
Pulse pressure variation (PPV) and pleth variability index (PVI) are widely used in clinical practice as indicators of the responsiveness to fluid therapy in patients receiving mechanical ventilation.
- Conditions
- Pulse Pressure Variation, Stroke Volume Variation, Pleth Variability Index
- Trial name
- NCT06733389
- Testing
- peripheral waveform collection
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Bundang Hospital
Peripheral Vein, Arterial Wave Reflections
Deep Learning Model for Predicting a Peripheral Venous Waveform-based Pulse Pressure Variation
Pulse pressure variation is a monitoring index that indicates the response to fluid therapy in patients receiving mechanical ventilation, and is used as a reference for patients with unstable hemodynamic conditions.
- Conditions
- Peripheral Vein, Arterial Wave Reflections, Pulse Pressure Variation, Stroke Volume Variation
- Trial name
- NCT06734650
- Testing
- peripheral waveform collection
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Haemodynamics, Fluid Responsiveness
Factors Influencing of Pulse Pressure Variation (PPV)
The investigators studied the predictive value of PPV in the patients with different influencing factors;and the method to improve the predictive value,which can improve the application of PPV in ICU.
- Conditions
- Haemodynamics, Fluid Responsiveness, Pulse Pressure Variation
- Trial name
- FacPPV (NCT04802668)
- Testing
- Patients were ventilated with assist-control ventilation（A/C） mode at different tidal volume, spontaneous breathing and no spontaneous breathing
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Southeast University, China
Stroke Volume Variation, Pulse Pressure Variation
SVV and PPV Predict Fluid Responsiveness in Mechanically Ventilated Elderly Patients Under General Anesthesia
Although individualized or goal-directed approach has been advocated, a reliable index is still required to help monitor the volume status timely and efficiently.
- Conditions
- Stroke Volume Variation, Pulse Pressure Variation, Fluid Responsiveness, Fluid Therapy
- Trial name
- NCT04388995
- Testing
- volume expansion
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Goal-directed Fluid Therapy, Hemodynamics Instability
Multi-center Trial of Goal-directed Fluid Management Based on Pulse Pressure Variation Monitoring
Background: Intraoperative fluid therapy guided by mechanical ventilation-induced pulse-pressure variation (PPV) may improve outcomes after major surgery. It was tested this hypothesis in a multi-center study.
- Conditions
- Goal-directed Fluid Therapy, Hemodynamics Instability, High-risk Surgery, Pulse-pressure Variation
- Trial name
- GDTPPV (NCT03128190)
- Testing
- Pulse pressure variation monitoring
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto de Assistencia Medica ao Servidor Publico Estadual, Sao Paulo
Pulse Pressure Variation, Spontaneously Breathing
Pulse Pressure Variation in Spontaneously Breathing Patients
The investigators hypothesized that pulse pressure variation (PPV) could predict fluid responsiveness in spontaneously breathing patients undergoing anesthesia induction.
- Trial name
- NCT01402934
- Testing
- Hydroxyethyl starch solution (Voluven) infusion
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital