Clinical trials: Pulse Wave Velocity
Cerebrovascular Accident, Spinal Cord Injury
Measurement of Pulse Wave Velocity in Spinal Cord Injury and Stroke Patients
According to the theory of wave transmission, the speed of wave transmission is dependent on the nature of the transmission medium, which is the vessel wall for pulse wave transmission.
- Trial name
- NCT00172289
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Arteriosclerosis
Association Between Peripheral Artery Stiffness and Cardiovascular Disease
Arterial pulse wave velocity (PWV) is strongly correlated with atherosclerosis, and the PWV of carotid or femoral artery could predict the severity of arterial atherosclerosis.
- Trial name
- NCT00201565
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Carotid Artery Diseases, Healthy Volunteers
Multicenter Normal Reference Study of Carotid Artery Ultrafast Pulse Wave Velocity (UFPWV)
To establish the range of BS and ES (m/s) of normal carotid artery by using ultrafast pulse wave velocity (UFPWV), and to explore the influencing factors.
- Trial name
- NCT03351127
- Testing
- Carotid ultrasound examination
- Where
- 44 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Chronic Kidney Disease, Hypertension
Arterial Stiffness in Children and Young People With Hypertension and Chronic Kidney Disease
Age related stiffening and hardening of the arteries is often a slow process, but some conditions such as chronic kidney disease (CKD), seem to increase the rate at which the arteries stiffen even during childhood.
- Trial name
- ART-KIDS (NCT07768865)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy Subjects
Investigation of Vascular Relaxing Effects of Candesartan and Pioglitazone.
The study is designed to test the hypothesis in healthy subjects that candesartan and pioglitazone provide additional vascular relaxing or modulating effects in addition to their blood-pressure and blood glucose level reducing…
- Trial name
- NCT00154037
- Testing
- Pioglitazone (drug) and/or candesartan (drug)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Cardiovascular Health During Prolonged Sitting
Effect of Chocolate Consumption Prior to Prolonged Sitting on Cardiovascular Health in Young Women
This randomized controlled crossover trial investigates the acute effects of consuming dark, milk, and white chocolate before prolonged sitting on cardiovascular health in healthy young women .
- Trial name
- CHOC-SIT (NCT07556627)
- Testing
- dark chocolate, Milk Chocolate, White Chocolate
- Where
- Saudi Arabia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- King Saud University
Carotid Artery Diseases
A Multicenter Study of Ultrafast Pulse Wave Velocity in Obese Chinese Han Adults
Ultrafast pulse wave velocity (UFPWV) is a novel non-invasive method developed recently to evaluate pulse wave velocity (PWV). This multi-center clinical trial aims to evaluate the feasibility of UFPWV in the evaluation of the…
- Trial name
- NCT05455099
- Testing
- Carotid ultrasound examination 1, Carotid ultrasound examination 2
- Where
- 22 sites in China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Prehypertension, Gout
Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure
High normal blood pressure, also called prehypertension, is a significant problem. High uric acid in the blood, the same thing that causes gout, may cause higher blood pressures.
- Conditions
- Prehypertension, Gout, Pulse Wave Velocity, Hypertension
- Trial name
- NCT01472692
- Testing
- Febuxostat
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Arterial Disease, Frail Elderly Syndrome
Relationship Between Digital Vascular Function Measured by EndoPAT® in elderlY Patients and Arterial Stiffness
Due to the aging of populations worldwide, we observe an increase of age-related diseases and loss of autonomy with consequent personal, social, medical and economic implications.
- Conditions
- Arterial Disease, Frail Elderly Syndrome, Stiffness, Vascular, Endothelial Degeneration
- Trial name
- ENDY (NCT04651894)
- Testing
- reactive hyperaemia index measurement
- Where
- France
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Hypertension, Autonomic Dysfunction
Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals
The goal of this observational study is to assess arterial stiffness and autonomic regulation of blood pressure and heart rate in healthy adults and people with arterial hypertension during orthostatic stress and graded physical…
- Conditions
- Hypertension, Autonomic Dysfunction, Orthostatic Hypotension
- Trial name
- NCT07482462
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Healthy Volunteers
Photoplethysmographic Measurements of Pulse Wave Velocity (PWV) and Blood Pressure (BP)
Theoretically, there is a correlation between the PWV and the value of the BP, mediated by the distensibility of the segment of artery where the measurements take place.
- Trial name
- MEPPAVOP (NCT05393401)
- Testing
- VOP1k
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy Volunteers, Vascular Ehlers Danlos Syndrome
Non-Invasive Quantitative Imaging of Human Local Arterial Wall Elasticity Using Supersonic Shear Imaging
Arterial stiffness is associated with increased risk of cardiovascular events and death. Most of existing technique need dedicated device for arterial stiffness evaluation and indirect calculation of intra arterial pressure.
- Trial name
- ULTRAFASTECHO (NCT01096264)
- Testing
- SSI and SphygmoCor® evaluations
- Where
- France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Pulmonary Disease, Chronic Obstructive
Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)
More patients with chronic obstructive pulmonary disease (COPD) die from cardiovascular disease than direct pulmonary complications.
- Trial name
- NCT01398943
- Testing
- Tetrahydrobiopterin (BH4), Antioxidant Cocktail
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Augusta University
Arterial Stiffness
Pulse Wave Velocity and Hemodynamic Response During Anesthesia Induction in Hypertensive Patients
Hypertension is a disease with increasing and serious complications all over the world. In particular, the incidence of hypertension increases with advancing age.
- Trial name
- AS (NCT05155514)
- Testing
- Mobil-O-Graph PWA
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Healthy
L-NMMA Dose-response Study in Healthy Subjects
The purpose of this study is to investigate the effect of different levels of nitric oxide inhibition on blood pressure and arterial stiffness in healthy subjects.
- Trial name
- NCT01070940
- Testing
- NG-monomethyl-L-arginine (L-NMMA)
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Arterial Stiffness, Oral Health
Predication of Arterial Stiffness in Healthy Adults by Oral Health and Chewing Assessments
INN.oral.HEALTH is an sub-study embedded in the Innsbruck Health Promotion Program (INN.HEALTH). The study investigates whether oral health, oral structure, and oral function provide additional information for understanding…
- Conditions
- Arterial Stiffness, Oral Health, Mastication, Deglutition
- Trial name
- INNoralHEALTH (NCT07736222)
- Testing
- Dentition and Occlusal Status Assessment, Oral Health Assessment Tool, Maximum Bite Force Measurement
- Where
- Austria
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Metabolic Syndrome
NWT03 and Arterial Stiffness
Rationale: Subjects with the metabolic syndrome have an increased risk of developing cardiovascular disease and a twofold risk of developing hypertension.
- Trial name
- NCT02561663
- Testing
- NWT-03, an egg-white protein hydrolysate
- Where
- Netherlands
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Newtricious R&D BV
Arterial Stiffness, Dysbiosis
Lifestyles, Arterial Aging and Intestinal Microbiota (MIVAS III Study)
This is an observational cross-sectional study whose objective is to analyse associations between the intestinal and salivate microbiota with lifestyles (eating patterns, physical activity, tobacco and alcohol consumption)…
- Trial name
- NCT04924907
- Where
- 2 sites in Spain
- Volunteers
- 1,015 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Biomédica de Salamanca
Hypertension
Endothelin Receptor Function and Acute Stress
Our bodies respond differently to stress. Animal studies by the investigators have found that endothelin-1 plays a role in regulating blood pressure in response to stress.
- Trial name
- End-Stress (NCT02116335)
- Testing
- Bosentan
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Augusta University
Sickle Cell Anemia, Sickle Cell Disease
Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose
The CADRE study is a multinational observational cohort of patients with sickle-cell disease (SCD) in five west and central sub-Saharan African countries.
- Trial name
- CADRE (NCT03114137)
- Where
- 13 sites in Cameroon, Côte d’Ivoire and 4 more
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Cardiologie et Développement