Clinical trials: Puncture
Labor Pain, Epidural
A Comparison Between 2 Methods of Local Anesthetic Administration for Maintaining Labor Analgesia After Dural Puncture Epidural
Intermittent epidural bolus technique opens a new era of interest for maintaining labor anlagesia. The study examines programmed intermittent epidural bolus technique on a scheduled basis to provider-administered bolus anlgesia…
- Conditions
- Labor Pain, Epidural, Pain, Labor
- Trial name
- NCT05034211
- Testing
- Programmed intermittent bolus epidural, Provider administered analgesia on patient request
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aretaieio Hospital
Premature Infant, Breast Feeding, Exclusive
Amphia Premature Infant Pain Study
Last thirty years, many research was performed concerning pain in the newborn. These investigations showed us the negative effects of pain in the neonatal period.
- Conditions
- Premature Infant, Breast Feeding, Exclusive, Puncture Skin
- Trial name
- APIP (NCT01276366)
- Testing
- breast feeding, supplemental breast milk, sucrose
- Where
- Netherlands
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Amphia Hospital
Analgesia
Comparison of Standard Epidural and Dural Puncture Epidural Analgesia in Open Gynecological Surgery Techniques
The aim of this study is to compare the effectiveness of standard epidural and dural puncture epidural analgesia techniques used under NOL guidance.
- Trial name
- NCT05408052
- Testing
- Dural Puncture Epidural (DPE), Standart Epidural
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pruritus
Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick
To determine the effective dose and the time course, the dermal blood flow response to histamine will be evaluated at different doses (5 µg, 15 µg and 50 µg).
- Trial name
- NCT04399213
- Testing
- 50 µg Histamine, 15 µg Histamine, 5 µg Histamine
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pain
Association With Spinal Needle-puncture Pain and Menstrual Phase
This prospective observational study aimed to evaluate the relationship between menstrual phase cycles and spinal needle-puncture pain during spinal anesthesia in female patients of reproductive age.
- Trial name
- NCT05481255
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Labor Pain, Analgesia
ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia
To estimate the dose of bupivacaine required to achieve initial effective comfort in 90% of patients (ED90) via the epidural (DPE or EPL) technique in women undergoing labor after receiving a lidocaine "test dose"
- Trial name
- NCT05543694
- Testing
- Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Allergy Skin, Allergy
NeoMatriX Wound Matrix Collagen Dressing Skin Prick Test
The objective of this study is to investigate the potential of NeoMatriXTM Wound Matrix to cause an allergic response to healthy volunteers using a skin prick test.
- Conditions
- Allergy Skin, Allergy, Dermatitis, Allergic Contact
- Trial name
- NCT03522675
- Testing
- NeoMatriX Wound MatriX Collagen Dressing
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- NeXtGen Biologics, Inc.
Headache
Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache
We hypothesized that; intrathecal administration of neostgmine in spinal anesthesia may have a beneficial role in reduction of the incidence or severity of PDPH.
- Trial name
- NCT04905953
- Testing
- Neostigmine
- Where
- Egypt
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Cairo University
PreTerm Neonate
Effect of Nursing Interventions on Pain and Salivary Cortisol Levels During Heel Stick in Preterm Newborns
Babies born before the thirty-seventh gestational week are called preterm or premature. Most preterm newborns require Neonatal Intensive Care Unit (NICU) care depending on their gestational age and clinical condition.
- Trial name
- NCT06628232
- Testing
- pacifier with breast milk, heel heating, interventions combined
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Arterial Puncture
Simple Psychological Interventions and Cryoanalgesia
This study aims to explore the effect of using simple psychological interventions and cryoanalgesia for reducing arterial punctures pain and anxiety in critically ill patients
- Trial name
- NCT06661187
- Testing
- Cryoanalgesia, Psychological instructions, Routine care
- Where
- 2 sites in Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Pruritus
Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.
In order to validate the accuracy and reliability of the histamine skin prick model for histaminergic itch and vasodilation, the dermal blood flow response induced by a histamine skin prick will be evaluated after the…
- Trial name
- NCT04399148
- Testing
- Desloratadine 5 mg, Aprepitant 125 mg, Ketotifen 1 MG
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Infection, Candida
Early Diagnosis of Candidiasis in Premature Infants
This observational study evaluated the performance of new lab tests in detecting candida species fungal infections in extremely low birth weight (ELBW) infants quickly and accurately.
- Conditions
- Infection, Candida, Candidiasis, Infant, Newborn
- Trial name
- Candida (NCT00109525)
- Where
- 20 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Traumatic Lumbar Puncture
The Effect of Bedside Ultrasound Assistance on the Proportion of Successful Infant Spinal Taps
The reported rate of unsuccessful spinal taps in children, especially young infants, is high. Our hypothesis is that ultrasound assistance can improve the success rate of spinal taps.
- Trial name
- NCT02133066
- Testing
- Bedside Ultrasound-Assisted Site Marking, Mindray M7 Ultrasound, Routine lumbar puncture
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Hemodialysis Patients
Effect on Pain and Comfort Associated With Fistula Puncture
Purpose This study was carried out as the design of the targeted design in terms of targeting and comfort in the patient with hemodialysis.
- Trial name
- NCT05574595
- Testing
- Music theraphy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Spinal Column, Lumbar Puncture
Comparison of Lateral Decubitus and Upright Sitting Positions in Measuring Intervertebral Space Via Ultrasound in Obese Volunteers
The aim of the study is to compare the lateral decubitus and upright sitting positions in determining the intervertebral space measured by ultrasound in participants whose body mass index was greater than 30 and older than…
- Conditions
- Spinal Column, Lumbar Puncture, Ultrasonography, Position
- Trial name
- NCT07315451
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Newborn
Pain and Comfort Levels During Heel Stick Blood Sampling in Newborns
Aim: The study was designed to determine the effect of Buzzy® and Shotbloker® application on pain and comfort levels in newborns during heel pricking. Method:The study was a randomised controlled trial.
- Trial name
- NCT07081048
- Testing
- Buzzy®.Group, ShotBlocker Group
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Allergic Reaction
Epidemiology of Pecan Nut Allergy
IgE-mediated food allergy can manifest with reactions ranging from hives to anaphylactic shock. The diagnosis is based on the confirmation of sensitization to the food allergen by skin tests (prick) and the determination of…
- Trial name
- PEC-ALL (NCT05185362)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
HIV Positive
Thinking and Memory Problems in People With HIV
Background: People with human immunodeficiency virus (HIV) can sometimes develop thinking and memory problems. These problems can vary widely, from few symptoms to severe problems with memory and concentration.
- Trial name
- NCT01875588
- Where
- United States
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Postdural Puncture Headache
Prediction of Post-dural Puncture Headache in Parturients Undergoing Elective Caesarean Section
The parturients are at particular risk of post dural puncture headache (PDPH) because of their sex, young age, and the widespread application of spinal and epidural anesthesia.
- Trial name
- NCT03464253
- Testing
- Performance of the transcranial Doppler (TCD)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Newborn, Maternal Voice
The Effect of Maternal Voice and Music Therapy on Pain and Stress During Heel Prick Testing in Newborns
During the adaptation process to the extrauterine environment, healthy newborns face procedures such as hepatitis B vaccination, vitamin K injection, blood sugar monitoring, bilirubin or metabolic disease screening.
- Conditions
- Newborn, Maternal Voice, Music Therapy, Heel Prick Testing
- Trial name
- NCT07773792
- Testing
- Music Therapy, Maternal Voice
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi