Clinical trials: Puncture
Labor Pain, Labor Analgesia
Impact of Dural Puncture Epidural Versus Traditional Lumbar Epidural on Onset of Labor Analgesia
This study is to examine the onset of pain relief with two different methods of labor epidural. The traditional labor epidural involves the placement of numbing and anti-pain medicine in the epidural space which surrounds the…
- Trial name
- NCT02412969
- Testing
- Lumbar Epidural, Dural Puncture Epidural
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Toxoplasma Infections
Point of Care Testing for Presence of Current and or Previous T. Gondii Infection
This is part of a feasibility study to compare the predicate standard FDA cleared test for serum to a point of care test Toxoplasma ICT IgG-IgM BK produced by LD Bio Diagnostic.
- Trial name
- NCT04474132
- Testing
- toxoplasma ICT IgG-IgM BK
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Infertility, Female, Oocyte Maturation
Second Phase of the Pilot Study for Obtaining Mature Oocytes by in Vitro Maturation in Oocyte-donor Women
In vitro maturation (IVM) is a technique for obtaining potentially fertilizable oocytes from immature oocytes. An oocyte must be mature both nuclearly and cytoplasmically in order to be competent in the reproductive process.
- Trial name
- MIVODON-II (NCT06103383)
- Testing
- Controlled ovarian stimuation, Oocyte pick up, Oocyte in vitro maturation
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Central Venous Catheterization
Effect of the Bevel Direction of Puncture Needle on Success Rate and Complications During Central Venous Catheterization
To test the hypothesis that approaching the internal jugular vein with the needle bevel down would produce less injury to the vessel wall compared to the bevel up approach during central venous catheterization.
- Trial name
- NCT01003366
- Testing
- bevel direction during central venous catheterization
- Where
- South Korea
- Volunteers
- 338 people
- Sponsor
- Seoul National University Hospital
Nursing Caries, Pain
The Effect of Hand Puppets and Kaleidoscope on Pain and Fear in Preschool Children
This study aimed to determine the effects of hand puppets and kaleidoscopes on some emotional parameters in preschool children who underwent skin prick testing at the pediatric allergy and immunology outpatient clinic.The study…
- Conditions
- Nursing Caries, Pain, Fear of Pain
- Trial name
- NCT06512857
- Testing
- Hand puppet method, Kaleidoscope method
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Firat University
Postdural Puncture Headache, Regional Anesthesia Morbidity
Postdural Punction Headache After Ceserian Section
The aim of this study is to compare the effect of spinal needle type on postdural puncture headache in patients who will undergo cesarean section.
- Conditions
- Postdural Puncture Headache, Regional Anesthesia Morbidity, Pregnancy Related
- Trial name
- NCT05777694
- Testing
- Patients who underwent cesarean section under spinal anesthesia with 25 gauge spinal needle, Patients who underwent cesarean section under spinal anesthesia with 26 gauge spinal needle, Patients who underwent cesarean section operation under spinal anesthesia with 27 gauge spinal needle
- Where
- Turkey (Türkiye)
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Pain, Anxiety
The Effect of ShotBlocker on Symptoms of Pain, Anxiety, and Cortisol Hormone Levels
The aim of this study is to evaluate the effect of Shotblocker, administered during lumbar puncture, on patients' pain levels, anxiety levels, and cortisol levels (a physiological stress indicator).
- Trial name
- NCT07880496
- Testing
- Intervention Group, Control
- Volunteers
- 68 people
- Sponsor
- Ataturk University
Postdural Puncture Headache
Prediction of Post-dural Puncture Headache in Parturients Undergoing Elective Caesarean Section
The parturients are at particular risk of post dural puncture headache (PDPH) because of their sex, young age, and the widespread application of spinal and epidural anesthesia.
- Trial name
- NCT03464253
- Testing
- Performance of the transcranial Doppler (TCD)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Lumbar Disc Herniation, Percutaneous Endoscopic Lumbar Discectomy
Randomized Controlled Clinical Study of Biplanar Ultrasound-guided Puncture of Lumbar Interforamen
The goal of this clinical trial is to compare Xplane ultrasound with radiography for guidance of lumbar interforamen puncture in patients with lumbar disc herniation.
- Conditions
- Lumbar Disc Herniation, Percutaneous Endoscopic Lumbar Discectomy, Three-dimension Ultrasound, Learning Curves
- Trial name
- NCT06315803
- Testing
- Real-time 3D Xplane ultrasound
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Yi Mao
Headache, Post-Dural Puncture
Sphenopalatine Blockade Versus Clinical Treatment
Post-dural puncture headache leads to high morbidity and cost to the health system. Pregnant women have a higher incidence than other population groups.
- Trial name
- NCT04148846
- Testing
- Dypirone, Sphenopalatine block, Ketoprofen
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
Anesthesia; Adverse Effect, Spinal and Epidural, Headache, Complications; Anesthesia, Spinal and Epidural, in Pregnancy
Comparison of Two Spinal Needles Regarding Postdural Puncture Headache
The aim of the study is to observe the rate of postdural puncture headache observed after spinal anesthesia in cesarean section patients. Two kind of spinal anesthesia needles will be used: 1.
- Trial name
- NCT01821807
- Where
- Turkey (Türkiye)
- Volunteers
- 256 people
- Sponsor
- Adiyaman University Research Hospital
Postdural Puncture Headache, Post-Lumbar Puncture Headache
Incidence of Headache Following an Unintentional Dural Puncture
The purpose of this study is to evaluate the use of intrathecal morphine administration following an unintentional dural puncture, to decrease the incidence of post dural puncture headaches (PDPH) in obstetric patients.
- Conditions
- Postdural Puncture Headache, Post-Lumbar Puncture Headache, Cerebrospinal Fluid Leaks
- Trial name
- NCT01977898
- Testing
- Morphine, Saline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Radial Artery Cannulation
Biplanar Handheld Ultrasound for Transradial Artery Puncture
Radial artery puncture is commonly used to obtain vascular access for cerebral angiography and neurointerventional procedures. Conventional ultrasound guidance usually provides either a short-axis or a long-axis view of the…
- Trial name
- NCT07708532
- Testing
- Biplanar handheld ultrasound system, Conventional high-frequency linear-array ultrasound system
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Shanghai Fourth People's Hospital Tongji University
Post-Dural Puncture Headache, Low Pressure Headache
Non-Luer Butterfly Needle With One-way Valve for the Epidural Blood Patch: Does it Alter Blood Clotting?
The Department of Health recommends using equipment which prevents wrong route drug administration. However, the epidural blood patch requires equipment that connects to the intravenous and epidural route.
- Trial name
- NCT03420352
- Testing
- Thromboelastography
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Post-Lumbar Puncture Headache
Headache After Diagnostic Lumbar Puncture
The objectives of this study are to investigate the effects of needle design, needle size and stylet reinsertion on the risk for headache after diagnostic LP (lumbar puncture, Post-LP headache).
- Trial name
- HELPUmeå (NCT03960749)
- Testing
- Sprotte 25G needle, stylet reinserted, Sprotte 25G needle, stylet not reinserted, Sprotte 22G needle, stylet reinserted
- Volunteers
- 1,000 people
- Sponsor
- Jonatan Salzer
Quality Health Care
Dural Puncture Epidural Vs Standard Epidural Technique in Parturient Receiving Continuous Labour Epidural Infusion
The goal of this study is to evaluate the quality and safety of labor analgesia by comparing the use of Dural puncture epidural technique to Standard epidural technique while maintaining labor analgesia by means of continuous…
- Trial name
- NCT06653036
- Testing
- Dural puncture epidural, Standard Epidural Technique
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Allergic Rhinitis, Conjunctivitis
Efficacy of the Anti-Bet v 1 Monoclonal Antibodies (Given Subcutaneously) to Reduce Allergic Rhinitis and Conjunctivitis Symptoms and Skin Test Reactivity Upon Exposure to Birch Allergen in Adult Participants
Primary objective: To assess the efficacy of a single dose of the anti- Bet v 1 monoclonal antibodies (mAb(s ) in the reduction of allergic nasal symptoms during an out-of-season birch allergen environmental exposure unit (EEU)…
- Trial name
- NCT05430919
- Testing
- REGN5713, REGN5714, REGN5715
- Where
- 3 sites in Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Urolithiasis
A Prospective Comparison of Fluoroscopic, Sonographic or Combined Approach for Renal Access in Percutaneous Nephrolithotomy
Purpose: The aim of this present study is to compare the result of fluoroscopy, ultrasonography (US) and US combined with fluoroscopy in the guidance of minimally invasive percutaneous nephrolithotomy (MPCNL).
- Trial name
- NCT02266381
- Testing
- US-guided renal access, Fluoroscopy-guided renal access, US combined with fluoroscopy-guided renal access
- Where
- China
- Volunteers
- 450 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Labor Pain
Comparison of Dural Puncture Epidural Versus Conventional Epidural for Labour Analgesia in Primigravida
This study aims to compare the analgesic efficacy and safety of the Dural Puncture Epidural (DPE) technique versus the Conventional Epidural (CE) technique for labor analgesia in primigravida.
- Trial name
- NCT06766812
- Testing
- epidural set
- Volunteers
- 60 people
- Sponsor
- Sohag University
IV Line Placement With Ultrasound
Ultra-portable Ultrasound vs. Standard Ultrasound to Help Place a Peripheral Catheter in Patients at Risk of Difficult Puncture
The placement of an intravenous (IV) line is a common procedure when treating adult patients in critical care, in the emergency room or in the operating room.
- Trial name
- NCT06296264
- Testing
- Standard ultrasound, Ultra-portable ultrasound
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon