Clinical trials: Pupil Assessment
Pupillary Dilation Effect During Cycloplegic Refraction
Comparing Efficacy and Safety of CTO0303 in Pediatric Subjects
This is a prospective randomized study compared with active control arm.
- Trial name
- NCT06609525
- Testing
- CTO0303-A, CTO0303-B, CTO0303-C
- Where
- South Korea
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Parkinson Disease
Assessment of Pupil Light Responses in Patients With Parkinson Disease
Parkinson diseases (PD) is the second most common degenerative disease of the central nervous system. The development of early diagnostic biomarkers may help identify at-risk individuals and allow precocious interventions at the…
- Trial name
- NCT04117555
- Testing
- Pupil response to light stimuli
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Small Pupil
Evaluation of an Iris Dilatation Ring in Cataract Surgery (ADICC-ID)
During cataract surgery, it is necessary to dilate the iris in order to remove the crystalline lens and position the implant. The diameter of the optical implant being 6 mm, in case of capsulorhexis crystalline access 5.5 mm, the…
- Trial name
- ADICC-ID (NCT02434588)
- Testing
- Bhattacharjee ring
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Intensive Care, Pupil Assessment
Pupillometry Use & Professional's Inspection : Leveling Subjectivity
This prospective, non interventionneal, mono-centric study aims to evaluate the accuracy and quality of pupil assessment among three different groups: senior physicians, anesthesiology residents, and nurses.
- Conditions
- Intensive Care, Pupil Assessment, Pupillometry, Neurological Examination
- Trial name
- PUPILS (NCT06733207)
- Testing
- Pupil examination
- Where
- France
- Volunteers
- 30 people
- Sponsor
- CHU de Reims
Myopia
An Investigation of Topical Ophthalmic Low-Dose Atropine on Pupil Size and Accommodation
The goal of this clinical study is to learn about the short-term physiological effects of low-dose atropine in healthy volunteers.
- Trial name
- NCT07674966
- Testing
- Atropine 0.01% Ophthalmic Solution, Atropine 0.02% Ophthalmic Solution, Atropine 0.05% Ophthalmic Solution
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, Berkeley
Literacy
Promoting Pupils' Physical Literacy
This pilot study aims to test the feasibility and acceptability of a previously developed and tested physical literacy (PL) intervention.
- Trial name
- 3PL (NCT05822024)
- Testing
- Promoting Pupils' Physical Literacy Intervention
- Where
- 3 sites in Denmark
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Center for Clinical Research and Prevention
Pain
Pain Assessment During General Anesthesia
During general anesthesia, two treatments are used : hypnotic and opioid treatment. Opioid treatment is used for pain assessment.
- Trial name
- DOLANS (NCT01303471)
- Testing
- opioid (remifentanyl)
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sleep Apnea Syndrome, Obstructive, Drowsiness
Ocular Parameters in Patients With Sleep Apnea
The aim of this study is to assess the ocular parameters of drowsiness in patients with diagnosed Obstructive Sleep Apnea Syndrome through objective methods of ocular imaging and subjective evaluation methods (questionnaire)
- Conditions
- Sleep Apnea Syndrome, Obstructive, Drowsiness, Blinking, Concentration Ability Impaired
- Trial name
- NCT05911737
- Testing
- Short video and Questionnaire
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Pupil Examination
Monochromatic Digital-Pupillometry With Two Automated Devices in Comparison to Manual Measurements on Digital Photographs
Retrospective, analysis of three different methods to measure patients' pupil diameters
- Trial name
- NCT02978092
- Volunteers
- 15 people
- Sponsor
- University Hospital Tuebingen
Presbyopia, Near Vision
Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia
A Multi-Center, Randomized, Double-Masked, Placebo-Controlled Phase 3 Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Treatment of Presbyopia
- Conditions
- Presbyopia, Near Vision, Miosis, Eye Diseases
- Trial name
- NCT06045299
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution
- Where
- 19 sites in China
- Volunteers
- 300 people
- Sponsor
- Corxel Pharmaceuticals
Mydriasis
Evaluation of Pupil Dilation Speed With the MAP Dispenser
1 mist or 2 mists of the study drug will be administered to both eyes according to a pre-specified randomization plan to determine the effect on pupil dilation
- Trial name
- SPEED (NCT04907474)
- Testing
- tropicamide-phenylephrine fixed combination ophthalmic solution
- Where
- Mexico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Myopia
Effects of Low Concentration Atropine on Pupillary Size and Accommodative Amplitude
To assess the two-week ocular responses, especially on pupillary size and accommodative amplitude, of nightly application of 0.01% or 0.02% or 0.03% atropine eye drops in children with myopia who were randomized to use of three…
- Trial name
- NCT03699423
- Testing
- 0.01% atropine eye drops, 0.02% atropine eye drops, 0.03% atropine eye drops
- Where
- Vietnam
- Volunteers
- 58 people
- Sponsor
- Hai Yen Eye Care
High-intensity Interval Training
Effect of a 4-week Fun Fast Interval Training (FFIT) Activity Programme on Physical Fitness and Quality of Life in Adolescent School Pupils
Low-volume high-intensity interval exercise training may improve aspects of health and fitness in young people, but the effect of this type of exercise on quality of life has yet to be assessed.
- Trial name
- NCT02759432
- Testing
- High-intensity interval exercise training
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Teesside University
Brain Injuries, Traumatic
Assignment of the Verbal Component Score and Addition of Pupil Reaction to the Glasgow Coma Scale
In this study, it is aimed to determine the prognostic value of GCS-P and the GCS-P score, which is formed by assigning a verbal score, in patients with traumatic brain injury, where all parameters can be evaluated.
- Trial name
- NCT05767502
- Testing
- GCS-Pupil score
- Where
- Turkey (Türkiye)
- Volunteers
- 199 people
- Sponsor
- Uludag University
Hypoxic Encephalopathy
The Neurological Pupil Index (NPi) on Intensive Care Unit (ICU) Trial
The trial will evaluate the use of the "Neurological Pupil index" NPi, measured with the digital pupillometer (NeurOptics) compared to clinical examination for better reliability.
- Trial name
- NPI-ON-ICU (NCT01920347)
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Pupil Constriction
Evaluation of NV701 (Pilocarpine 1.25%) Compared With Vuity (Pilocarpine 1.25%) on Pupil Size in Subjects With Presbyopia
Randomized contralateral eye study to evaluate the effect of one-time dosing of NV701 versus commercially available 1.25% pilocarpine solution on pupil size.
- Trial name
- NCT06783686
- Testing
- NV701, Pilocarpine 1.25% Eye drop
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Novus Vision LLC
Analgesia, Anesthesia
Analgesic Depth Evaluation During General Anesthesia With Dexmedetomidine-remifentanil Infusion. A Pilot Study
The aim of this study is to verify the feasibility of an evaluation of the depth of analgesia during an opioid sparing anesthesia (OSA) carried out with continuous infusion of dexmedetomidine in addition to general multimodal…
- Trial name
- NCT05785273
- Testing
- Pupillometer
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Università degli Studi di Brescia
Sexual Harassment
Evaluation of Virtual Course to Increase Knowledge in Sexual Harassment,Prevention and Sanction Policies of a University
Sexual harassment is the behavior of sexual or sexist connotation unwanted by the affected person. Despite being considered as gender-based violence, victims of sexual harassment can be of both sexes.
- Trial name
- NCT04021849
- Testing
- Face-to-face Class, Asynchronous Virtual Class
- Where
- Peru
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Pupil Dilation
Evaluation of the FIM - a Non Invasive Device for Temporarily and Quick Pupil Dilation (Mydriasis)
The objective of this clinical trial is to evaluate the FIM optimal configuration and confirm the safety and performance/efficacy of the FIM when exposed to a larger and more varied population of users.
- Trial name
- TP 7601-CL (NCT01946828)
- Testing
- FIM
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Regional Anesthesia, Horner Syndrome
Cerebral Blood Flow Evaluation With Trancranial Doppler After Interscalene Nerve Block
The purpose of this study is to assess cerebral blood flow velocity (CBFV) following regional anesthesia for shoulder surgery. The results of this study will help to further understand the physiologic effect of the interscalene…
- Conditions
- Regional Anesthesia, Horner Syndrome, Cerebral Blood Flow
- Trial name
- CBF-TCD (NCT04642612)
- Testing
- TCD Measurement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University