Clinical trials: Pupillary Constriction
Presbyopia, Near Vision
Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia
A Multi-Center, Randomized, Double-Masked, Placebo-Controlled Phase 3 Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Treatment of Presbyopia
- Conditions
- Presbyopia, Near Vision, Miosis, Eye Diseases
- Trial name
- NCT06045299
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution
- Where
- 19 sites in China
- Volunteers
- 300 people
- Sponsor
- Corxel Pharmaceuticals
Management of Intraoperative Floppy-iris Syndrome and Small Pupils With Different Mechanical Devices
Methods to Manage Intra-operative Floppy-iris Syndrome and Poor Pupil Dilation in Cataract Surgery
Cataract surgery is one of the most frequently performed surgeries worldwide and complications are rare. However, there are factors that increase the risk of complications, such as poor pupil dilation and intra-operative floppy…
- Trial name
- IFIS (NCT01778959)
- Testing
- Malyugin Ring, Iris hooks, standard OVD
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Surgery
Topical 0.4% Ketorolac and Vitreoretinal Surgery
To determine whether use of topical 0.4% ketorolac has any effect on pupil size during vitreoretinal surgery.
- Trial name
- NCT00576329
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Emory University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Miosis Disorder, Intraoperative Floppy Iris Syndrome
Use of APX 100 Device for Small-pupil Cataract Surgery and Intraoperative Floppy-iris Syndrome
The purpose of the study is to gather clinical data and safety information on the use of APX 100 device for small-pupil cataract surgery and the management of intraoperative floppy iris syndrome (IFIS) during cataract surgery.
- Trial name
- NCT01693575
- Testing
- Pupil expansion with APX 100 device
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- Meir Medical Center
Drug Induced Constipation
Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118
Study in healthy volunteers to investigate the effects of Quinidine on the Pharmacokinetics of NKTR-118
- Trial name
- NCT01533155
- Testing
- Nektar 118, Quinidine, Morphine
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- AstraZeneca