Clinical trials: Purging
Bulimia Nervosa
Self-Control in Bulimia Nervosa
This study examines the influence of acute fasting and eating on self-control in adult females with and without bulimia nervosa (BN).
- Trial name
- NCT04409457
- Testing
- fasting state, fed state, magnetic resonance imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Eating Disorders, Anorexia Nervosa
Eating Disorder Dynamic Intervention
The goal of this study is to develop and test a digital program to help people with eating disorders in their everyday lives. The program uses brief surveys and sensor data collected by smartphones to understand when someone may…
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder
- Trial name
- EDDI (NCT07600671)
- Testing
- Eating Disorder Dynamic Intervention
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Trustees of Dartmouth College
Acute Myelogenous Leukemia, Myelodysplastic Syndrome
Study of Gelonin Purging of Autologous Stem Cells for Transplantation
Patients with Acute Myelogenous Leukemia or Myelodysplastic are able to achieve a complete remission but fail to achieve a prolonged disease-free survival.
- Trial name
- NCT00043810
- Testing
- Gelonin, Busulfan, Fludarabine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Anorexia in Adolescence, Anorexia Nervosa
3-Dimensional Optical Scanning to Assess and Monitor Malnutrition in Eating Disorders (3D-ED) Study
People with anorexia nervosa often become medically unstable because of severe malnutrition and require hospitalization for nutritional rehabilitation.
- Conditions
- Anorexia in Adolescence, Anorexia Nervosa, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- 3D-ED (NCT07726524)
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Francisco
Eating Disorders, Anxiety
Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders
The study is to evaluate the feasibility of using a non-invasive brain stimulation device in a sample of inpatients with eating disorders (ED).
- Trial name
- NCT07017322
- Testing
- Alpha-Stim AID
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rogers Behavioral Health
Bulimia Nervosa, Eating Disorder
Rapid Response to Day Hospital Treatment in Bulimia Nervosa and Purging Disorder
Treatments for bulimia nervosa (BN) have relatively high rates of nonremission and relapse, meaning that improving treatments is a high priority in this area.
- Trial name
- CBT-RR (NCT02444065)
- Testing
- Cognitive Behavior Therapy (CBT), Motivational Interviewing (MI)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Binge Eating, Purging (Eating Disorders)
Emotion Regulation in Binge Eating and Purging Among Adolescents
The study will examine the neural and behavioral correlates of emotion regulation in adolescents engaging in binge eating and/or purging and healthy adolescents.
- Trial name
- NCT03429114
- Testing
- Magnetic resonance imaging
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mantle Cell Lymphoma
Treatment of Mantle Cell Lymphoma at Diagnosis for Patients Under 65 Years
Phase II study to test in first line the VAD (Vincristine Adriablastine Dexamethasone) + C (Chlorambucil ) regimen associated to rituximab ( R-VAD + C ) in a cohort of young patients under 66 years with a mantle cell lymphoma and…
- Trial name
- NCT00285389
- Testing
- Adriblastin, dexamethasone, Chlorambucil
- Where
- 3 sites in France
- Volunteers
- 39 people
- Sponsor
- French Innovative Leukemia Organisation
Anorexia Nervosa/Bulimia, Anorexia in Adolescence
Oral Naltrexone In Pediatric Eating Disorders
The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo.
- Conditions
- Anorexia Nervosa/Bulimia, Anorexia in Adolescence, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- ONPED (NCT05073679)
- Testing
- Naltrexone Hydrochloride, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rosemary Claire Roden
Eating Disorders, Binge Eating
Naltrexone Neuroimaging
The purpose of this open-label, pilot study is to evaluate fMRI as a biomarker of opioid antagonism in adolescents with ED. Modulation of brain activation will be examined in regions of interest by fMRI using a food-specific and…
- Conditions
- Eating Disorders, Binge Eating, Purging (Eating Disorders)
- Trial name
- EDIT-N2 (NCT04935931)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Mercy Hospital Kansas City
Bulimia Nervosa, Bulimia
Acquisition and Utilization of Skills Using Innovative Smartphone Application for Regular Eating
The study seeks to evaluate the acceptability, feasibility, target engagement, and validity of an innovative smartphone application with ecological momentary interventions to augment cognitive behavioral therapy for bulimia…
- Conditions
- Bulimia Nervosa, Bulimia, Binge Eating, Purging
- Trial name
- ACQUIRE (NCT03673540)
- Testing
- CBT+ application
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Drexel University
Eating Disorders (Excluding Anorexia Nervosa), Binge-Eating Disorder
Building Healthy Eating and Self-Esteem Together for University Students
Eating disorders (EDs) are a critical concern on college campuses. Moreover, since the COVID-19 pandemic, ED prevalence has increased by 62% in university women and 140% in university men.
- Trial name
- BEST-U (NCT07060534)
- Testing
- Building Healthy Eating and Self-Esteem Together for University Students, Present-Centered Therapy
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Kansas
Bulimia Nervosa, Bulimia
Improving Treatments for Bulimia Nervosa: Innovation in Psychological Interventions for Regulating Eating
The purpose of the study is to test a novel, acceptance-based behavioral treatment for bulimia nervosa (BN) in adults. This treatment is a type of individual psychotherapy called Nutritional Counseling And Acceptance-Based…
- Conditions
- Bulimia Nervosa, Bulimia, Binge Eating, Purging (Eating Disorders)
- Trial name
- INSPIRE (NCT02716831)
- Testing
- Nutritional Counseling & Acceptance-based Therapy, Cognitive Behavioral Therapy for Eating Disorders
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Drexel University
Multiple Myeloma, Post-transplant MRD-guided Maintenance Therapy
Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma
To learn if giving elranatamab before and after an autologous stem cell transplant (ASTC) can help to control newly diagnosed, high-risk MM.
- Conditions
- Multiple Myeloma, Post-transplant MRD-guided Maintenance Therapy, Pre-transplant Purging
- Trial name
- NCT06207799
- Testing
- Elranatamab, Lenalidomide, Plerixafor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Anorexia Nervosa Restricting Type, Anorexia Nervosa, Binge Eating/Purging Type
CGM in Patients With ED's
To determine the accuracy of continuous glucose monitoring (CGM) with point of care (POC) fingerstick glucose monitoring and venous blood glucose in patients with eating disorders, specifically anorexia nervosa, restricting…
- Conditions
- Anorexia Nervosa Restricting Type, Anorexia Nervosa, Binge Eating/Purging Type, ARFID, Avoidant Restrictive Food Intake Disorder
- Trial name
- CGM (NCT05603481)
- Testing
- Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Denver Health and Hospital Authority
Bulimia Nervosa, Binge Eating Disorder
Using Visual Feedback to Influence Rapid Response in the Treatment of Eating Disorders
This study has two aims: 1) to test the validity of an eating disorder symptom checklist against an established clinical interview; and 2) to examine whether providing eating disorder patients with visual graphs of their symptom…
- Trial name
- NCT02940613
- Testing
- Visual feedback of symptom frequency
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Lymphoma, Non-Hodgkin
Enrichment & Purging of Stem Cells in Non-Hodgkin's Lymphoma
To evaluate the role of purging the hematopoietic cell graft on outcomes for non-Hodgkin's Lymphoma.
- Trial name
- NCT00186355
- Testing
- high dose chemo then auto hematopoietic cell transplant
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Stanford University
HIV Infection
Safety and Effect of The HDAC Inhibitor Panobinostat on HIV-1 Expression in Patients on Suppressive HAART
The purpose of this study is to assess the safety and ability of panobinostat to re-activate HIV transcription in latently infected CD4+ T-cells among HIV-infected patients on stable antiretroviral therapy
- Trial name
- CLEAR (NCT01680094)
- Testing
- Panobinostat
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Eating Disorders, Binge Eating
Naltrexone Neuroimaging in Teens With Eating Disorders
Using a randomized, placebo-controlled, crossover study, this study will evaluate functional magnetic resonance imaging (fMRI) as a pharmacodynamic biomarker of opioid antagonism in adolescents with eating disorders.
- Conditions
- Eating Disorders, Binge Eating, Purging (Eating Disorders), Bulimia Nervosa
- Trial name
- NN-RCT (NCT05509257)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Mercy Hospital Kansas City
Leukemia
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses…
- Trial name
- NCT00002761
- Testing
- filgrastim, recombinant interferon gamma, busulfan
- Sponsor
- Columbia University