Clinical trials: Quadriceps
Knee Osteoarthritis, Osteo Arthritis Knee
Effectiveness of Physical Therapy in Stem Cell Transplant Recipients for Knee Osteoarthritis
Knee osteoarthritis has been considered as 11th highest contributor factor to nonfatal burdens in the world. It is considered one of the most common degenerative diseases of synovial joint and major cause of muscle impairment…
- Conditions
- Knee Osteoarthritis, Osteo Arthritis Knee, OA Knee
- Trial name
- NCT05959902
- Testing
- Forward Walking, Physiotherapy Exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 48 people
- Sponsor
- Dow University of Health Sciences
ACL - Anterior Cruciate Ligament Rupture
Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings
To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied.
- Trial name
- SQuASH (NCT03896464)
- Testing
- Soft tissue hamstring autograft, Quadriceps tendon autograft
- Where
- 6 sites in Canada, Japan
- Volunteers
- 352 people
- Sponsor
- McMaster University
Osteoarthritis, Knee
Ultrasound Imaging of Quadriceps Muscle in Patients With Knee Osteoarthritis
Echo intensity (EI) assessment using ultrasonography helps monitoring disease-induced muscle quality changes. However, there are no study investigating the reliability of EI in patients with knee osteoarthritis (OA).
- Trial name
- NCT04660071
- Testing
- ultrasonographic Assessment,, Echo intensity Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Muscle Strength
Mode Specific Effects of Isokinetic Training of Hamstring on Hamstring to Quadriceps Ratio
Mode specificity of eccentric and concentric isokinetic training have been examined in previous studies but with conflicting results.
- Trial name
- NCT05229367
- Testing
- Eccentric isokinetic training, Concentric isokinetic training
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Saud University
Anterior Cruciate Ligament Reconstruction Rehabilitation, Quadriceps Muscle Function
Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction
After knee surgery for a torn ACL, many women struggle with weak thigh muscles for years, partly due to reduced brain signals to these muscles.
- Trial name
- NCT07128602
- Testing
- active transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Arcadia University
Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries
Correlation Between Psychological Readiness, Knee Function, and Isokinetic Performance After Anterior Cruciate Ligament Reconstruction (ACLR) Using Peroneus Longus Tendon Graft (PL-ACL-2025)
This clinical trial aims to investigate the correlation between psychological readiness, knee function, and isokinetic performance after anterior cruciate ligament reconstruction (ACLR) using the Peroneus Longus tendon graft…
- Conditions
- Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries, Knee Injuries
- Trial name
- PL-ACLR (NCT07201597)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Leg Injury, Bone Fracture
Electromiographic Analysis of the Quadriceps After Trauma
The lower limb is the region most affected by fractures in the human body. The magnitude of the trauma can cause injuries to structures adjacent to the fracture, promoting joint instability and consequently predisposition to…
- Trial name
- NCT05574556
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Quadriceps Function Monitored With Electromyography
Compare the Quadriceps Function of Adductor Canal Block Versus Femoral Nerve Block With Electromyography Following Total Knee Arthroplasty
Adductor canal block and femoral nerve block are the most commonly used nerve blocks for pain control after total knee arthroplasty.
- Trial name
- NCT04778774
- Testing
- Nerve block
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Patellofemoral Pain, PFP
Effects of Attentional Focus Strategies During Isokinetic Quadriceps Training on Strength and Functional Performance in Individuals With Patellofemoral Pain Syndrome.
Patellofemoral pain syndrome (PFPS) is a multifactorial musculoskeletal condition that is common particularly among young and physically active individuals, negatively affecting activities of daily living and physical…
- Trial name
- NCT07384858
- Testing
- Internal focus group, External focus
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Orthopedic Disorder, Anterior Cruciate Ligament Injuries
Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT
The choice of autograft for ACL reconstruction continues to be debated. To date, there has only be one completed randomized controlled trial with quad tendon to BTB and the tendon included a bone plug.
- Trial name
- NCT05461326
- Testing
- Quad tendon, BTB
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Neuromuscular Blockade
Transmucular Quadratus Lumborum Block: Potential Quadriceps Muscle Weakness
The aim of this study is to examine whether the administration of the TQL block cause motor block of the lumbar plexus and thereby quadriceps muscle weakness.
- Trial name
- NCT05023343
- Testing
- Ropivacaine, Quadriceps muscle strength, Timed Up and Go
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Post-operative Quadriceps Weakness, Post-operative Quadriceps Inhibition
Effect of a Home-based Electrical Stimulation on Quadriceps Function After Knee Surgery
The purpose of this study is to determine if a home-based electrical stimulation (ES) program is more effective than the standard of care (SOC) at improving quadriceps function, functional outcomes, patient reported outcomes, and…
- Conditions
- Post-operative Quadriceps Weakness, Post-operative Quadriceps Inhibition, Adherence to Post-operative Treatment, Post-operative Lower Extremity Function
- Trial name
- NCT02058862
- Where
- 2 sites in United States
- Volunteers
- 87 people
- Sponsor
- University of Kentucky
Anterior Cruciate Ligament Reconstruction
Effectiveness of Kneehab in Strengthening the Quadriceps of Patients Post Anterior Cruciate Ligament (ACL) Reconstruction
Prospective, controlled, randomized, single blind study in patients undergoing rehabilitation following anterior cruciate ligament reconstruction. 96 patients were randomly assigned to one of three groups.
- Trial name
- NMES (NCT00737750)
- Testing
- Kneehab, Poli-Stim, Control
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Bio-Medical Research, Ltd.
Primary Hyperparathyroidism
Gait and Balance Parameters Before and After Parathyroidectomy in Patients With Primary Hyperparathyroidism
This study will evaluate how Quadriceps Femoris muscle fatigue protocol affect the spatio-temporal gait parameters, gait symmetry and balance in individuals with primary hyperparathyroidism before and after parathyroidectomy.
- Trial name
- NCT03713671
- Testing
- gait analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Anterior Cruciate Ligament Reconstruction
Whole Body Vibration in Individuals Submitted to ACL
The purpose of this study is to analyze the immediate effects of two exercises protocols on the whole body vibration, on the strength of the thigh muscles, joint position sense of the knee and balance in individuals submitted to…
- Trial name
- NCT02609971
- Testing
- Vibration at 50 Hz
- Volunteers
- 46 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Critical Illness
Quadriceps Muscle Activation and Oxygenation Responses During Usual Care Compared to Individualized Interval and Constant Work Rate Bed-cycling. An Experimental Study.
### Study Summary - AcuteBike-ICU Bed-cycling is commonly used as part of early rehabilitation in critically ill patients in the intensive care unit (ICU).
- Trial name
- AcuteBike-ICU (NCT07882719)
- Testing
- usual care constant work rate bedcycling, Individualized constant work rate bedcycling, Individualized interval bedcycling
- Volunteers
- 29 people
- Sponsor
- KU Leuven
Mechanically Ventilated Patients, Severe Pneumonia
Impact of a High-Protein Diet on Clinical Outcomes in Mechanically Ventilated Patients With Severe Pneumonia
prospective, comparative, observational study will be conducted at the Critical Care Department, Fayoum University Hospital, to evaluate the impact of a high-protein diet versus a standard-protein diet in mechanically ventilated…
- Trial name
- NCT07634328
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University
Spinal Cord Injuries, Brain Injuries
Pilot Study for Peripheral Neuromuscular Electrical Stimulation of the Quadriceps Muscle
Feasibility study of a new medical device that will evaluate the usability and effectiveness of a cycle ergometer device associated with neuromuscular electrical stimulation (FES cycling).
- Conditions
- Spinal Cord Injuries, Brain Injuries, Muscle Atrophy
- Trial name
- NCT05888714
- Testing
- Experimental FES cycling, Comparator FES cycling, Conventional physical therapy
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo General Hospital
Patellofemoral Pain Syndrome, Chondromalacia Patellae
Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain
The purpose of this study is to determine if interventions applied at a distant site, lumbopelvic region (manipulation and TENS), have a similar effect as interventions applied locally at the knee (TENS) on quadriceps force…
- Conditions
- Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
- Trial name
- NCT01434966
- Testing
- Lumbopelvic Manipulation, TENS- Spine, TENS- Knee
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Creighton University
Thyroid
Thyroid Autotransplantation in Quadriceps Femoris Muscle
providing an almost natural ectopic thyroid in patients undergoing total thyroidectomy, remains a challenging subject that can benefits patients with a non-pharmacological substitute for their normal gland.
- Trial name
- NCT04684953
- Testing
- Throid autotransplantation, Hormone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University