Clinical trials: Quality of Breathing
Cystic Fibrosis
Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis - A Safety and Efficacy Study
The purpose of this study is to determine the efficacy and safety of chronic treatment with inhaled dry powder mannitol in subjects with cystic fibrosis.
- Trial name
- NCT00446680
- Testing
- Mannitol
- Where
- 29 sites in Australia, Ireland and 1 more
- Volunteers
- 340 people
- Sponsor
- Syntara
Cough, Upper Respiratory Infection
A Novel Formulation of Pasteurized Maple Cough Syrup Compared With Placebo on Nocturnal Cough and Sleep Quality in Infants With Upper Respiratory Infection
Cough is a frequent symptom in children and infants and is one of the most common reasons parents visit a healthcare provider for their child.
- Conditions
- Cough, Upper Respiratory Infection, Nocturnal Cough
- Trial name
- NCT01588249
- Testing
- Pasteurized maple syrup
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Zarbee's Inc.
Patient Ventilator Interactions
Analysis and Evaluation of Asynchronies Between NIV Patients and Their Prisma VENT or LUISA Ventilator
This study aims to analyze the types, rates, and patterns of disturbances between the breathing of patients receiving non-invasive ventilation and their ventilator (patient-ventilator asynchronies, PVA) during routine therapy…
- Trial name
- NCT07768748
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Löwenstein Medical Technology GmbH & Co. KG
Obese, Sleep Apnea, Obstructive
Eval EarlySense Bet Lowenstein Sleeplab
The study objective is to collect heart rate, respiration rate and motion data of patients admitted to sleep lab and to determine the accuracy level of the EarlySense system vs.
- Conditions
- Obese, Sleep Apnea, Obstructive, Central Apnea, Sleep Disorders
- Trial name
- NCT01978340
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- EarlySense Ltd.
Cancer Pain, Quality of Life
Safety and Efficacy of Inhaled Cannabis For the Uncontrolled Pain Relief in Patients With Advanced Cancer
This phase 2 multicenter clinical trial assess the safety and efficacy of inhaled PPP001 to relieve the pain in 78 advanced cancer patients with uncontrolled symptoms.
- Conditions
- Cancer Pain, Quality of Life, Pain, Acute, Cannabis Use
- Trial name
- PLENITUDE (NCT04042545)
- Testing
- PPP001
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Tetra Bio-Pharma
Pulmonary Disease, Chronic Obstructive
Inhaled Bronchodilator Association and Quality of Life in Patients With Chronic Obstructive Pulmonary Disease
A pharmaco-epidemiological, observational study that aimed at assessing in a prospective manner the evolution of Quality of Life (QOL) in chronic obstructive pulmonary disease (COPD) patients treated with inhaled bronchodilators
- Trial name
- NCT02176564
- Testing
- inhaled bronchodilator
- Volunteers
- 2,639 people
- Sponsor
- Boehringer Ingelheim
Nasal Obstruction
Quality of Life Impact of Nasal Airway Treatment With Aerin Medical Device
Evaluation of long-term (5-year) quality of life after nasal airway obstruction treatment with the Aerin Vivaer Stylus
- Trial name
- NCT03290300
- Testing
- Vivaer Stylus
- Where
- 8 sites in United States
- Volunteers
- 39 people
- Sponsor
- Aerin Medical
Asthma
A Study to Compare the Efficacy of Fluticasone Furoate/Vilanterol Inhalation Powder With Usual Inhaled Corticosteroids (ICS)/Long Acting Beta Agonists (LABA) in Persistent Asthma
The combination of FF, an ICS and VI, an orally inhaled LABA has been developed as a once-daily combination therapy for the long-term maintenance treatment of asthma in adults and children >=12 years of age.
- Trial name
- NCT02446418
- Testing
- Fluticasone Furoate, Vilanterol, Fluticasone propionate
- Where
- 93 sites in France, Germany
- Volunteers
- 423 people
- Sponsor
- GlaxoSmithKline
Asthma
Control of Asthma Patients Symptomatic on Inhaled Corticosteroids
The purpose of the study is to determine whether IPL512,602 is safe and effective for the treatment of asthma symptoms in patients who remain symptomatic on a background therapy of inhaled corticosteroids.
- Trial name
- NCT00330070
- Testing
- IPL512,602 20 mg once daily
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- Inflazyme Pharmaceuticals Ltd
Asthma, Perennial Allergy
Clinical Effects of Temperature Controlled Laminar Airflow (TLA)
The purpose of this study is to determine whether clean air administered to the breathing zone with Temperature controlled Laminar Airflow (TLA) during night is effective in the treatment of perennial allergic asthma.
- Trial name
- NCT00987064
- Testing
- Temperature controlled Laminar Airflow (Protexo)
- Where
- 2 sites in Sweden
- Volunteers
- 28 people
- Sponsor
- Airsonett AB
Common Cold, Cough
A Clinical Evidence Study Evaluating Quality of Life Parameters Following Treatment With Robitussin
The purpose of this Real-World Evidence study is to generate real world data from participants with cough associated with the common cold, evaluating the effects in two arms with commercially available cough syrups on…
- Trial name
- NCT06716645
- Testing
- Robitussin Maximum Strength Cough and Chest Congestion DM, Robitussin Maximum Strength Nighttime Cough DM
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- HALEON
Pulmonary Arterial Hypertension
Efficacy of Ventavis Used in Real-life Setting.
This is a registry of patients diagnosed with pulmonary arterial hypertension, scheduled for treatment with Ventavis. Typical clinical measures and quality of life will be prospectively followed in 12 months period.
- Trial name
- SPHERA (NCT01355380)
- Testing
- Inhaled iloprost (Ventavis, BAYQ6256)
- Where
- Poland
- Volunteers
- 55 people
- Sponsor
- Bayer
Cough
Clinical Response of Syrup Hydryllin® in Pakistani Subjects With Cough in Routine Practice
A cough is one of the most common medical complaints accounting for as many as 30 million clinical visits per year. It is the single most prevalent symptom on presentation to a physician's office.
- Trial name
- HYD-EFFECT (NCT05129761)
- Testing
- Syrup Hydryllin
- Where
- Pakistan
- Volunteers
- 320 people
- Sponsor
- The Searle Company Limited Pakistan
Asthma
Omalizumab Use and Asthma-Related Quality of Life in Patients With Severe Persistent Allergic Asthma
This study investigated asthma-related quality of life in Brazilian patients using omalizumab.
- Trial name
- NCT00567476
- Testing
- Omalizumab, Inhaled corticosteroids (ICS), Long-acting beta 2-adrenergic agonist (LABA)
- Where
- Brazil
- Volunteers
- 116 people
- Sponsor
- Novartis
Parkinson Disease (PD), Parkinson's Disease
Real-world Patient Experiences With Inbrija®
Parkinson's disease can cause OFF episodes, when medication effects wear off and symptoms return, affecting movement, daily activities, comfort, and wellbeing.
- Conditions
- Parkinson Disease (PD), Parkinson's Disease, Off Episodes of Parkinson Disease
- Trial name
- INHALE-PD (NCT07797790)
- Testing
- Levodopa inhalation powder
- Where
- 2 sites in Austria
- Volunteers
- 120 people
- Sponsor
- Merz Therapeutics GmbH
Chronic Obstructive Pulmonary Disease
Long-term Effects of Non-invasive Ventilation in Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) Patients
In this multicenter study the comparison of the mass flow distribution and redistribution versus the relative blood flow per lobe (as a surrogate for Ventilation/ Perfusion (V/Q) matching) with functional respiratory imaging…
- Trial name
- NCT01592656
- Testing
- Functional Respiratory Imaging, Lung compliance measurement, Non-invasive ventilation (Respironics)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 40 people
- Sponsor
- FLUIDDA nv
Anesthesia, General
Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Required General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on Cardiovascular System in Common Clinical Practice
The main objective of this post-marketing observational study is to collect data from the use of general anesthesia in patients undergoing any surgery to create local recommendations.
- Trial name
- SEVOPROTECTION (NCT01282203)
- Where
- 12 sites in Kazakhstan
- Volunteers
- 1,122 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Respiratory Insufficiency, Sleep Disordered Breathing
Adjustment of Mask Pressure, for Bilevel Positive Airways Pressure Therapy, by Automated Algorithm
The aim of the study is to test the hypothesis that an automated algorithm for desired mask pressure improves breathing pattern and sleep quality in patients with hypercapnic ventilatory failure.
- Trial name
- NCT01403584
- Testing
- AutoVPAP with addition of AutoEPAP, AutoVPAP with EPAP manually selected
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- ResMed
Sleep Apnea, Obstructive
Adherence and Quality of Life of CPAP for Obstructive Sleep Apnea
A multicentre, randomized controlled trial (RCT) design.The control group followed the usual treatment, while the intervention group (PIMA) followed the treatment with an adapted and flexible care plan depending on…
- Trial name
- PIMA1-JO-PR (NCT04691479)
- Testing
- Motivational Interview (MI) & Adherence Follow-Up, Adherence Follow-Up
- Where
- Spain
- Volunteers
- 129 people
- Sponsor
- Air Liquide Healthcare Spain
Sleep, Pollution; Exposure
Investigating the Effect of Daily CARDIO® Capsules Supplementation on Improved Sleep in Healthy, Urban-Dwelling Adults
This study aims to explore the impact of supplementation with CARDIO® whole salmon oil capsules on healthy adult participants with sleep disruption related to particulate matter pollution.
- Conditions
- Sleep, Pollution; Exposure, Cough
- Trial name
- NCT06768970
- Testing
- CARDIO® salmon oil
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA