Clinical trials: Quality of Life (QOL)
Hematological Malignancy, Prehabilitation
Investigation of the Effects of Prehabilitation Education Delivered Through a Mobile Compatible Website on Quality of Life and Symptoms in Patients Undergoing Hematopoietic Stem Cell Transplantation
Aim of the Study: The aim of this study is to examine the effect of prehabilitation education delivered via a mobile-compatible website on the quality of life and symptom evaluation of patients undergoing hematopoietic stem cell…
- Conditions
- Hematological Malignancy, Prehabilitation, Patient Education
- Trial name
- NCT07066592
- Testing
- Prehabilitation education provided via mobile compatible website
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Anxiety, Depression
Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers
This study is being done to test the effects of Managing Anxiety from Cancer (MAC) therapy on anxiety compared to usual care, in patients and their caregivers.
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- NCT03168971
- Testing
- Managing Anxiety from Cancer (MAC)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Dysphagia, Esophageal, Esophageal Cancer
Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer
This study validates 3 well known dysphagia scores for dysphagia due to malignancies of the oesophagus and gastro-oesophageal junction and to the Swedish language.
- Trial name
- NCT03066167
- Testing
- Validation of different dysphagia scores
- Where
- Sweden
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Diabetes Mellitus, Telemedicine
Community- and mHealth-Based Integrated Management of Diabetes in Primary Healthcare in Rwanda
The Home Based Care Practitioners (HBCPs) programme has been established by the Rwandan Ministry of Health in response to the shortage of health professionals.
- Conditions
- Diabetes Mellitus, Telemedicine, Community Health Workers
- Trial name
- D²Rwanda (NCT03376607)
- Testing
- HBCP programme, mobile health application
- Where
- 9 sites in Rwanda
- Volunteers
- 209 people
- Sponsor
- University of Aarhus
Anxiety and Fear
Effect of Music Therapy on the Anxiety Level of Patients During the Administration of Ocular Intravitreal Injections
Introduction Ocular intravitreal injection is a widely used ophthalmic invasive technique to administer medication directly inside the patient's eye.
- Trial name
- NCT05904392
- Testing
- Music
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Uncontrolled Type 2 Diabetes Mellitus, Severe Periodontitis
A Comparison of Single-Stage Full-Mouth Disinfection With Quadrant-Based Scaling and Root Planing in Patients With Uncontrolled Type 2 Diabetes and Severe Periodontitis: An Assessment of Its Impact on Quality of Life
This study evaluated the effects of a single-stage full mouth disinfection (FMD) protocol versus a quadrant-based tooth surface cleaning and root planing (Q-SRP) protocol on changes in clinical periodontal parameters over a…
- Trial name
- NCT07598071
- Testing
- Quadrant based scaling and root planning, full mouth disinfeciton
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Pamukkale University
Dilated Cardiomyopathy
Bone Marrow Derived Adult Stem Cells for Dilated Cardiomyopathy
A randomised, double-blind, placebo-controlled trial to evaluate the role of intracoronary injection of progenitor cells compared to placebo injection in patients with Dilated Cardiomyopathy who have been pre-treated with G-CSF…
- Trial name
- REGEN-DCM (NCT01302171)
- Testing
- granulocyte colony stimulating factor (GCSF), bone marrow mononuclear cells
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Barts & The London NHS Trust
Chronic Obstructive Pulmonary Disease
Quality of Life in Daxas-treated Patients Older Than 18 Years With Severe Chronic Obstructive Pulmonary Disease (COPD) (DACOTA)
Chronic obstructive pulmonary disease (COPD) is a progressive and largely irreversible lung disease characterized by chronic bronchitis and/or emphysema, resulting in breathlessness, cough and sputum.
- Trial name
- DACOTA (NCT01285167)
- Testing
- Daxas
- Where
- 605 sites in Germany
- Volunteers
- 3,645 people
- Sponsor
- AstraZeneca
Functional Dyspepsia
Probiotic and Ginger Supplement for Symptoms and Quality of Life in Functional Dyspepsia (SUBTILE)
Functional dyspepsia (FD) is a frequent functional gastrointestinal disorder characterized by bothersome postprandial fullness, early satiety, epigastric pain, or burning, in the absence of any structural or metabolic cause.
- Trial name
- SUBTILE (NCT07212907)
- Testing
- Symbiosys® Stomalex (commercial name)
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Biocodex
Chronic Kidney Disease
A Study on Patients With Chronic Kidney Disease (CKD) to Assess Treatment Experience and Patterns, Effect of the Treatment, Patient Outcomes and Patient Quality of Life
DISCOVER CKD is an international observational cohort study in patients with CKD, comprising both prospective and retrospective patient cohorts.
- Trial name
- NCT04034992
- Where
- 43 sites in United States, Italy and 4 more
- Volunteers
- 1,052 people
- Sponsor
- AstraZeneca
Intention to Stay, Turnover Behavior
Exploring ProQOL, Health Status, Job Involvement and Turnover in Medical Professionals
The study design is a cross-sectional study. Purposive sampling will be conducted in three hospitals in the central of Taiwan. The participants will include physicians, nurse practitioners and nurses.
- Trial name
- NCT03385811
- Testing
- no intervention, only questionnaires survey
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Quality of Life (QOL), Mental Wellbeing
Arts for Wellness (AFW): Arts-Based Social Prescribing During Inpatient Rehabilitation for Older Adults in Singapore
This mixed-methods study examined whether Arts for Wellness (AFW), an artist-led arts programme introduced during inpatient rehabilitation, improves mental wellbeing among older adults in a Singapore community hospital, and…
- Conditions
- Quality of Life (QOL), Mental Wellbeing, Anxiety, Depression
- Trial name
- SPNAC (NCT07851467)
- Testing
- Arts for Wellness - Dance, Arts for Wellness - Literary arts
- Where
- Singapore
- Volunteers
- 288 people
- Sponsor
- SingHealth Community Hospitals
Irritable Bowel Syndrome, Quality of Life
Effect of Stress Ball on Irritable Bowel Syndrome
Objective: This study will be conducted to evaluate the effect of stress ball on symptom severity, quality of life, depression, anxiety and stress in patients with irritable bowel syndrome (IBS).
- Conditions
- Irritable Bowel Syndrome, Quality of Life, Depression, Anxiety
- Trial name
- NCT05931107
- Testing
- Stress ball practice group (Stress ball squeezing)
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Bedriye Cansu DEMİRKIRAN
Solid Tumors
Phase II Clinical Trial of Uncaria Tomentosa (Cat´s Claw) in Patients With Advanced Solid Tumors
Cat's claw (Uncaria tomentosa) is a native amazonic plant that exhibits anti-inflammatory and antitumor properties. Patients and methods: This prospective phase II study will assess the effects of a 100-mg dose of a dry extract…
- Trial name
- cat´sclaw (NCT02045719)
- Testing
- uncaria tomentosa (cat´s claw)
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- Faculdade de Medicina do ABC
Health-related Quality of Life, Emotional Well-being
Enhancing Health-related Quality of Life, Emotional Well-being and Reducing Anxiety: Integrated Psychoeducational Nursing Interventions in Patients Undergoing Modified Electroconvulsive Therapy
Background: Electroconvulsive Therapy (ECT) remains a highly effective intervention for severe psychiatric disorders yet concerns about cognitive and emotional side effects persist.
- Conditions
- Health-related Quality of Life, Emotional Well-being, Modified Electroconvulsive Therapy
- Trial name
- NCT07579819
- Testing
- - After baseline measurement, the 120 patients were randomly divided into two equal groups: Study (Intervention) group (n = 60): received the multidisciplinary psychiatric nursing intervention session, No intervention (observational study)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shereen
Cancer Of Prostate, Prostate Neoplasms
Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy
Background: Sometimes prostate cancer comes back after a person's prostate is removed. In this case, radiation is a common treatment. Radiation kills prostate cancer cells. It can be very effective.
- Conditions
- Cancer Of Prostate, Prostate Neoplasms, Prostate Cancer, Neoplasms of Prostate
- Trial name
- NCT03388619
- Testing
- Prostate bed with integrated boost, Prostate bed irradiation only, Whole Body Bone Scan
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Fibromyalgia
Combined Effects of Progressive Relaxation Exercises and Aquatic Therapy in Fibromyalgia.
Fibromyalgia, a chronic pain disorder, presents a significant challenge in healthcare due to its widespread musculoskeletal pain, tenderness, and a spectrum of associated symptoms.
- Trial name
- NCT06460636
- Testing
- progressive muscle relaxation therapy, aquatic therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Prostate Cancer
ABlative Radiotherapy (for) Unfavorable Prostate Tumors
Published clinical evidence confirms that a single dose of 24 Gy provides unprecedented long-term local control in primary and metastatic prostate cancer with safe toxicity profiles, provided that exposure of surrounding healthy…
- Trial name
- ABRUPT (NCT04831983)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Milano Bicocca
GBM, Depression
The Effect of Escitalopram on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients
Testing the effect of providing an antidepressant and anxiety-type escitalopram for patients with glioblastoma on patient's quality of life including the effect of treatment on mood and cognition during treatment.Two subgroups…
- Trial name
- Cipralex&GBM (NCT02623231)
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
MDS, MDS/MPN
Study Investigating Patient-Reported Outcomes in Lower-risk MDS Patients
PRO-RED is a prospective, longitudinal, and multicenter observational study. Enrolled patients will be followed for 6 months in at least monthly intervals in terms of their received red blood cell transfusions and routine…
- Trial name
- PRO-RED (NCT05582902)
- Where
- 11 sites in Austria, Germany
- Volunteers
- 60 people
- Sponsor
- University of Leipzig
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