Clinical trials: Quantitative Assessment
Primary Hyperparathyroidism, Bone Disease
Bone Architectural Parameters in Postmenopausal Women Affected With Primary Hyperparathyroidism
Bone lesions are frequent in primary hyperparathyroidism (PHPT). Conventional measurement by Dual-Energy X-ray Absorptiometry does not provide enough information about the bone impact of excessive parathyroid hormone (PTH)…
- Trial name
- MicrOs (NCT02539498)
- Testing
- HR-pQCT
- Where
- 3 sites in France
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Acute
Epidural Methadone in Healthy Volunteers
Epidurally administered opioid pain medications are important tools for postoperative pain control, but each agent has its own limitations.
- Trial name
- NCT03525509
- Testing
- Methadone hydrochloride, Morphine Sulfate
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- simon.haroutounian
Autism Spectrum Disorder (ASD)
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study
The goal of this observational study is to investigate the genetic and epigenetic mechanisms that may contribute to the development of Autism Spectrum Disorder (ASD) in individuals of different age groups.
- Trial name
- ASD-Omics-TR (NCT06662591)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Research and Treatment Society of Genetic Disorders
Healthy, Osteopenia
Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-BMD (NCT07187518)
- Testing
- Measurements with the POROUS R4C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine
- Where
- 2 sites in Germany
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Medial Knee Compartment Arthritis
Oxford Partial Knee Kinematics Gait Analysis Study
The objective of this study is to compare the effect on gait of unicompartmental knee arthroplasty (UKA), using the Oxford Partial Knee, versus normal knee.
- Trial name
- NCT01454908
- Testing
- Oxford Partial Knee
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The CORE Institute
Multiple Sclerosis
Evaluation of the Clinical Contribution of Quantitative MRI in Neuro-imaging
This study aims to develop the use of a quantitative MRI (qMRI) approach in neuroimaging for MS patients. To achieve this task the main goals of this study will be: to standardize and optimize qMRI protocols (acquisition time…
- Trial name
- NormaBRAIN (NCT07245589)
- Testing
- 3T MRI, 7T MRI, Clinical examination of MS patients
- Where
- France
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Rickets
Ultrasound Imaging and Quantitative Vibro-Acoustic Assessment of Rickets Under the Age of Ten
The goal of this study is to find out if the use of ultrasound pictures of bones can spot changes in the growth areas of children with rickets, a condition that affects how bones harden.
- Trial name
- NCT06385938
- Testing
- Ultrasound with quantitative vibro-acoustic assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy, Vision; Disorder, Loss
Associations Between Vision and Brain Function
Case-control studies and meta-analysis have reported that several ocular features, especially the thickness of the peripapillary retinal nerve fiber layer and visual acuity, are related to the brain degeneration and cognitive…
- Trial name
- NCT04226729
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Arthritis
Sensitization in Osteoarthritic Knees
Musculoskeletal pains represent a major part of pain complaints in patients. Moreover, the treatment of musculoskeletal pain conditions by currently available drugs is not optimal (Curatolo and Bogduk 2001).
- Trial name
- NCT00379184
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Simple Bone Cyst
Quantitative Ultrasound for the Evaluation of Simple Bone Cyst Healing
Simple bone cysts (SBCs), also known as unicameral bone cysts (UBCs), are benign bone lesions. Literature to date describes little agreement between clinicians on specific prognostic criteria for the prediction of cyst healing…
- Trial name
- NCT02616757
- Testing
- Sunlight Omnisense Quantitative Ultrasound
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Dentofacial Deformities, Orthognathic Surgery
Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking
Dentofacial deformities refer to morphological anomalies of the jaws. Their development during growth determines the shape of the lower third of the face and the type of dental occlusion.
- Conditions
- Dentofacial Deformities, Orthognathic Surgery, Social Perception, Eye Tracking
- Trial name
- OCHIRO (NCT06494709)
- Testing
- photographs
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Tooth Defect
Occlusal Contact Trueness Affected by Six Chairside CAD/CAM Ceramic Materials
The aim of this clinic self-control study was to evaluate the trueness of occlusal contact affected by six ceramic materials during chairside fabricating process and offer recommendations for occlusal offset according to…
- Trial name
- NCT05346744
- Testing
- Chairside CAD/CAM ceramic materials for dental restoration
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Dental Caries, Tooth Wear
DIMOH: New Digital Methods for Monitoring Oral Health. An in Vivo Assessment
The objectives of this study are i) to monitor the oral health of young people over a period of one year and ii) to assess the ability of a new intraoral scanner combining fluorescence with 3D imaging to detect and monitor…
- Trial name
- NCT04050306
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Chronic Liver Disease
Delta Radiomics for Liver Function Evaluation
To evaluate the feasibility and efficacy of delta radiomics-derived index based on Gd-EOB-DTPA enhanced MRI as a new imaging biomarker for the quantitative assessment of liver function.
- Trial name
- NCT05296434
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Systemic Lupus Erythematosus
Spine Quantitative Computed Tomography (QCT) for the Assessment of Osteoporosis on Children
The purpose of this study is to compare healthy children to children who have systemic lupus erythematosus (SLE). SLE is a childhood disease that has high risk for low bone mass and vertebral compression fractures.
- Trial name
- NCT01330368
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
IVF Treatment
Follicle Size and Oocyte Development
Studies have shown that the follicles greater in diameter was most likely to have a mature oocyte that was capable of fertilization and best suited for development into a high-quality embryo.
- Trial name
- AMJH (NCT03660813)
- Testing
- Follicle measurment, Ovitrelle ( Hcg 250 mcg), Decapeptyl ( GnRH Agonist 0.1 mg*2 )
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Alveolar Bone Loss
Minimally Invasive Ridge Splitting Versus the Conventional Open Flap Technique
The goal of this clinical trial is to compare implant stability, and crestal bone loss, when using minimal invasive ridge splitting versus convenient open flap technique.
- Trial name
- NCT06329362
- Testing
- Minimally invasive implantation, Open flap procedure for ridge expansion.
- Where
- 2 sites in Egypt, Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Royal College of Surgeons of Edinburgh
Emphysema, Pulmonary Emphysema
Clinical-ultrasonographic Assessment of Pulmonary Emphysema
The goal of this clinical trial is to identify correlations among data deriving from lung ultrasonographic (LUS) and tomographic evaluations of patients with panlobular or paraseptal emphysema, to improve the comprehension of…
- Trial name
- ESCULAPIO (NCT06533371)
- Testing
- Relationship between lung ultrasound and computed tomographic scan
- Where
- 4 sites in Italy
- Volunteers
- 1,628 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Female Sexual Dysfunction
Assessing the Effects of a Topically Applied Cream to Clitoral Blood Flow
The purpose of this study is to determine if blood flow to the clitoris is increased by topically applying a cream that causes increased blood flow. This will be measured with a sonogram.
- Trial name
- NCT01085981
- Testing
- arginine 20%, nicotinamide .01%, niacin.1%, in LipodermPG 50%, Topical study cream, GRAS cream
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Suburban Ob Gyn
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital