Clinical trials: Quantitative Assessment
Breast Cancer
Women's Experiences of Mammography: Quantitative Evaluation
Study will develop, validate and pilot measures to assess quality of experiences of mammography. Pilot data collection and analysis will investigate modifiable factors most important in determining quality of patient experiences…
- Trial name
- WEM-Quant (NCT02829905)
- Where
- United Kingdom
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Female Sexual Dysfunction
Assessing the Effects of a Topically Applied Cream to Clitoral Blood Flow
The purpose of this study is to determine if blood flow to the clitoris is increased by topically applying a cream that causes increased blood flow. This will be measured with a sonogram.
- Trial name
- NCT01085981
- Testing
- arginine 20%, nicotinamide .01%, niacin.1%, in LipodermPG 50%, Topical study cream, GRAS cream
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Suburban Ob Gyn
Acute Leukemia
Quantitative MRI of Bone Marrow in Patients With Acute Lymphoblastic Leukemia
The study is aimed at assessing changes in the bone marrow of patients from 6 to 18 years old with a diagnosis of acute lymphoblastic leukemia during chemotherapy.
- Trial name
- NCT04767165
- Testing
- MRI
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Autism Spectrum Disorder (ASD)
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study
The goal of this observational study is to investigate the genetic and epigenetic mechanisms that may contribute to the development of Autism Spectrum Disorder (ASD) in individuals of different age groups.
- Trial name
- ASD-Omics-TR (NCT06662591)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Research and Treatment Society of Genetic Disorders
Healthy Volunteers, Motor Deficits
Developing Effectiveness Evaluation and Therapeutic Programs of Rehabilitation
Using robotics, sensors, and sEMG to develop clinic-oriented quantitative effectiveness evaluation and individualized programs of rehabilitation
- Conditions
- Healthy Volunteers, Motor Deficits, Dysphagia
- Trial name
- NCT03979235
- Testing
- Motor function assessment
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Research Center for Rehabilitation Technical Aids
Periapical Periodontitis, Polymerase Chain Reaction
Quantitative Assessment of the Efficacy of Sweeps Laser Activation Systems
Aim of the present study was to determine the intraradicular microbiota of previously root canal-treated teeth with apical periodontitis using droplet digital polymerase chain reaction (ddPCR) and to investigate the antibacterial…
- Conditions
- Periapical Periodontitis, Polymerase Chain Reaction, Enterococcus Faecalis Infection
- Trial name
- NCT05718596
- Testing
- sweeps laser to use irrigation activation, PUI to use irrigation activation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seyda Ersahan, DDS, PhD
Ss-octa, Lid Margin Blood Flow Density
Quantitative Assessment of Lid Margin Vascularity Using SS-OCTA
To explore an optimized scan technique for the detection of lid margin vasculature
- Conditions
- Ss-octa, Lid Margin Blood Flow Density, MGD
- Trial name
- NCT06091722
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Major Depressive Disorder
Near Infrared Spectroscopy (NIRS) for Assessment of Depression
Develop a NIRSIT testing protocol that can be administered in the diagnostic setting and reliably distinguishes the symptoms and severity of depression, with the help of repeated measure (up to five visits per subject) comparison…
- Trial name
- NIRSIT (NCT04061148)
- Testing
- NIRSIT
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fatty Liver Disease, Nonalcoholic
Quantitative US for Evaluation of Hepatic Steatosis in MAFLD With UDFF
Ultrasound Derived Fat Fraction (UDFF) Evaluation of Metabolic Related Fatty Liver Disease (MAFLD) in obesity Patients Metabolic fatty liver disease (MAFLD), formerly known as Nonalcoholic Fatty Liver Disease (NAFLD), is the most…
- Trial name
- NCT06097338
- Testing
- bariatric surgery (BS)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
HIV Infections, Pneumococcal Infections
Safety of and Immune Response to a Pneumococcal Vaccine (PncCV) in HIV Infected and Uninfected Children
Infection by Streptococcal pneumoniae is a common invasive bacterial infection in HIV infected children. The purpose of this study is to determine the safety of and immune response to a pneumococcal polysaccharide-protein…
- Trial name
- NCT00099658
- Testing
- Pneumococcal polysaccharide-protein conjugate vaccine
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- CIPRA SA
Dental Caries, Tooth Wear
DIMOH: New Digital Methods for Monitoring Oral Health. An in Vivo Assessment
The objectives of this study are i) to monitor the oral health of young people over a period of one year and ii) to assess the ability of a new intraoral scanner combining fluorescence with 3D imaging to detect and monitor…
- Trial name
- NCT04050306
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
Pharmacological Effects of Neurapas® Balance and Pascoflair® 425 mg on Brain Activity in Healthy Volunteers
To evaluate the pharmacological effects of two herbal medicinal products (Neurapas balance and Pascoflair 425 mg) in comparison to placebo on brain activity.
- Trial name
- NCAG 5209 (NCT01047605)
- Testing
- Neurapas balance, Pascoflair 425 mg, P-Tabletten weiß
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Lymphedema, Lipedema
Multimodal Ultrasound for Differentiating Lymphedema and Lipedema
The aim of this observational study is to evaluate the diagnostic value of multimodal ultrasonography in differentiating between lymphedema and lipedema.
- Trial name
- NCT07489248
- Testing
- Multimodal Ultrasound Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Taste Sweet, Taste Salty
Taste Acuity and Caloric Intake After Acute Morphine Administration
This study will investigate the effects of acute morphine administration on taste acuity and how much a person eats. It is hypothesized that there will be a dose dependent decrease in taste acuity and dose dependent increase in…
- Conditions
- Taste Sweet, Taste Salty, Feeding Behavior
- Trial name
- NCT01763697
- Testing
- taste acuity assessment, Recorded meal
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Autosomal Dominant Polycystic Kidney Disease, Kidney Disease
New Quantitive MRI Parameters in Assessing Kidneys of Autosomal Dominant Polycystic Kidney Disease
The purpose of this study is to establish normal Magnetic Resonance quantitative values (tissues stiffness, Apparent Diffusion Coefficient values and Blood Oxygen Level Determination values for both renal cortex and medullary…
- Trial name
- MRI Pilot (NCT02250287)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Primary Hyperparathyroidism, Bone Disease
Bone Architectural Parameters in Postmenopausal Women Affected With Primary Hyperparathyroidism
Bone lesions are frequent in primary hyperparathyroidism (PHPT). Conventional measurement by Dual-Energy X-ray Absorptiometry does not provide enough information about the bone impact of excessive parathyroid hormone (PTH)…
- Trial name
- MicrOs (NCT02539498)
- Testing
- HR-pQCT
- Where
- 3 sites in France
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tooth Discoloration
Quantitative Evaluation of the Effect of Dehydration and Rehydration Levels on Tooth Color
This study aims to evaluate the dehydration and rehydration changes in teeth over time and the quantitative effect of these changes on natural tooth color in the clinic.
- Trial name
- NCT05620277
- Testing
- Mobile Dental Photography, Mobile Dental Photography with cross-polarization filter, Mobile Dental Photography with gray reference card
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Nocturnal Hypokinesia
Rotigotine Effect on Nocturnal Hypokinesia Compares to Placebo Control: A Quantitative Assessment by Wearable Sensors
Parkinson's disease (PD) is the neurodegenerative disease which is caused by Lewy bodies deposition in central and peripheral nervous system.
- Trial name
- NCT03098368
- Testing
- Rotigotine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Extrapyramidal Symptoms, Drug-induced Parkinsonism
A Computer-Assisted Tool for Objective Assessment of Extrapyramidal Symptoms
This prospective, single-center observational study aims to develop and validate a computer-assisted tool for the objective quantitative assessment of extrapyramidal symptoms (EPS).
- Conditions
- Extrapyramidal Symptoms, Drug-induced Parkinsonism, Akathisia, Drug-Induced, Tardive Dyskinesia (TD)
- Trial name
- NCT07715994
- Testing
- Computer-Assisted Objective Assessment of Extrapyramidal Symptoms
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center