Clinical trials: Quantitative Assessment
Chronic Obstructive Pulmonary Disease
Quantitative Study on HRCT Phenotype of COPD
To explore the HRCT phenotype of the combined COPD assessment staging system
- Trial name
- NCT04953611
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Nonalcoholic Fatty Liver Disease, Metabolic-associated Fatty Liver Disease
To Explore the Value of New MR Technology in Non-invasive Quantitative Assessment of Systemic Metabolism, Disease Status and Prognosis in Patients With Metabolic-Associated Fatty Liver Disease
The purpose of this study is to explore the value of new MR technology in assessing the systemic metabolism, disease status, and prognostic risk of metabolism-related fatty liver disease.
- Trial name
- NCT07149571
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Changes in EEG During and After Magnetic Stimulation
The Effect of Repetitive Transcranial Magnetic Stimulation on Brain Activity in Healthy Human Volunteers
The proposed study is designed to determine whether small changes in the positioning of a transcranial magnetic stimulation coil over the frontal parts of the brain cause different patterns of brain activation measured by…
- Trial name
- ERP (NCT01369264)
- Testing
- true left high frequency
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Breast Carcinoma
Quantitative Transmission Imaging Compared With MRI as Supplemental Screening for High Lifetime Risk of Breast Cancer
This clinical trial compares the use of quantitative transmission imaging (QTI) to standard of care MRI as a supplemental screening tool for patients with a high lifetime risk of breast cancer.
- Trial name
- NCT07216274
- Testing
- QT Ultrasound Breast Scanner, Questionnaire Administration
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer, Colorectal Adenoma
Quantitative Fecal Immunochemical Test for Detection of Colorectal Cancer and Precancerous Lesions in Sohag
Colorectal cancer is a major cause of cancer-related morbidity and mortality worldwide, and early detection significantly improves patient outcomes.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Sessile Serrated Lesion
- Trial name
- NCT07410546
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Healthy
Pharmacological Effects of Neurapas® Balance and Pascoflair® 425 mg on Brain Activity in Healthy Volunteers
To evaluate the pharmacological effects of two herbal medicinal products (Neurapas balance and Pascoflair 425 mg) in comparison to placebo on brain activity.
- Trial name
- NCAG 5209 (NCT01047605)
- Testing
- Neurapas balance, Pascoflair 425 mg, P-Tabletten weiß
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Renal Insufficiency, Chronic
Explore New Magnetic Resonance Technology in Assessment of Renal Dysfunction
Currently, renal biopsy is the gold standard for evaluating renal pathology and renal fibrosis, but it is invasive and carries the risk of serious complications; and the sampled tissue is only a small part of the kidney, which is…
- Trial name
- NCT06366529
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zhen Li
Non-alcoholic Fatty Liver Disease (NAFLD), Non-alcoholic Steatohepatitis (NASH)
Simultaneous Quantification of Liver Fat Content, Fatty Acid Composition, and Fibrosis Using Spin-lock MRI for Steatohepatitis Assessment
Non-alcoholic fatty liver disease is a major health problem worldwide. It includes simple steatosis and NASH which has inflammation in the liver, with or without fibrosis.
- Trial name
- NCT05384652
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
White Matter Hyperintensity, Multiple Sclerosis
Evaluation of the Reproducibility of the Measurement of the QSM Signal (Quantitative Susceptibility Mapping)
Many central nervous system pathologies have an inflammatory component, often associated with an accumulation of disability and more severe tissue damage.
- Trial name
- ERESI (NCT04465448)
- Testing
- MRI
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Juvenile Idiopathic Arthritis
Spine Quantitative Computed Tomography (QCT)
The purpose of this study is to compare healthy children to children who have a chronic illness called Juvenile Idiopathic Arthritis (JIA). JIA is a childhood disease that causes swollen joints that are often stiff and painful.
- Trial name
- Spine QCT (NCT00762879)
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Extrapyramidal Symptoms, Drug-induced Parkinsonism
A Computer-Assisted Tool for Objective Assessment of Extrapyramidal Symptoms
This prospective, single-center observational study aims to develop and validate a computer-assisted tool for the objective quantitative assessment of extrapyramidal symptoms (EPS).
- Conditions
- Extrapyramidal Symptoms, Drug-induced Parkinsonism, Akathisia, Drug-Induced, Tardive Dyskinesia (TD)
- Trial name
- NCT07715994
- Testing
- Computer-Assisted Objective Assessment of Extrapyramidal Symptoms
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Periapical Periodontitis, Polymerase Chain Reaction
Quantitative Assessment of the Efficacy of Two Irrigation Activation Systems
Aim of the present study was to determine the intraradicular microbiota of previously root canal-treated teeth with apical periodontitis using droplet digital polymerase chain reaction (ddPCR) and to investigate the antibacterial…
- Conditions
- Periapical Periodontitis, Polymerase Chain Reaction, Enterococcus Faecalis Infection, Irrigation Activation
- Trial name
- NCT05690763
- Testing
- XP-endo Finisher to use irrigation activation, EndoActivator to use irrigation activation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seyda Ersahan, DDS, PhD
Lower Extremity, Photoacoustic
Photoacoustic Tomography in Assessment of Lower Extremity Artery Disease
Lower extremity artery disease (LEAD) is characterized by low awareness rate and high missed diagnosis rate, leading to low treatment rate and high disabling mortality rate.
- Trial name
- NCT06579326
- Testing
- Photoacoustic imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence
Quantitative Assessment of Lumbar Facet Joint Degeneration, A Retrospective Study.
Observational study The purpose of this observational study was to understand the quantitative assessment of the degree of degeneration of lumbar facet joints, and to improve the Weishaupt grading system by using gray-scale curve…
- Conditions
- Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence, Facet Joint Disease
- Trial name
- NCT06786611
- Testing
- MRI
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Bipolar Disorder
Study to Assess the Effect of Food on the Concentration of GW273225 in the Body of Healthy Male and Female Volunteers
The rationale of this study is to assess whether or not food affects the absorption of GW273225 into the blood of healthy male and female volunteers in order to evaluate whether or not this drug should be given at a certain time…
- Trial name
- NCT00501865
- Testing
- GW273225
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Autosomal Dominant Polycystic Kidney Disease, Kidney Disease
New Quantitive MRI Parameters in Assessing Kidneys of Autosomal Dominant Polycystic Kidney Disease
The purpose of this study is to establish normal Magnetic Resonance quantitative values (tissues stiffness, Apparent Diffusion Coefficient values and Blood Oxygen Level Determination values for both renal cortex and medullary…
- Trial name
- MRI Pilot (NCT02250287)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Drug Effect
Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth
This study was to evaluate and compare garlic extract antibacterial effect when used as an intra-canal medicament in infected mature anterior teeth with calcium hydroxide and a mixture of calcium hydroxide and garlic, using real…
- Trial name
- Garlic (NCT05050071)
- Testing
- Allium Sativum, Polymerase chain reaction
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Interstitial Lung Disease
PRospective Evaluation of Interstitial Lung DIsease Progression With Quantitative CT
The interstitial lung diseases (ILD) are a heterogenous group of conditions with varying degrees of inflammation and scarring (fibrosis) of the lungs. ILD progression is unpredictable, making prognostication challenging.
- Trial name
- PREDICT-ILD (NCT05609201)
- Testing
- HRCT Thorax, Glycocheck Endothelial Glycocalyx Assessment, Blood biomarkers
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Shoulder Impingement
Dual-target Ultrasound Guided Corticosteroid Injection for Shoulder Impingement Syndrome
Subacromial injection is considered one of the best treatments for patients with subacromial impingement syndrome. The subacromial bursa is located between the deltoid muscle and the supraspinatus tendon.
- Trial name
- NCT04219527
- Testing
- Dual-target injection
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Horizontal Ridge Deficiency
Buccal Cortical Separation and Lateralization for Horizontal Ridge Augmentation
Cases with horizontal ridge deficiency less than what is possible for ridge splitting were recruited and the buccal cortex was totally separated and lateralized at the desired distance for augmentation
- Trial name
- NCT05286541
- Testing
- Lateralized buccal cortex with xenograft, Lateralized buccal cortex with autogenous particulate
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University