Clinical trials: Quantitative Neuromuscular Monitoring
Patients Undergoing General Anesthesia
A Comparative Study of the Next-Generation TetraGraph® and Mechanomyography Neuromuscular Monitors in Clinical Settings
Background: Neuromuscular monitoring plays a critical role in reducing postoperative residual neuromuscular blockade (PRNB), a significant risk factor for respiratory complications.
- Trial name
- MMG vs EMG NG (NCT07750405)
- Testing
- Mechanomiograph (MMG), Electromiograph (EMG)
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- University of Debrecen
Inflammatory Myopathy, Duchenne Muscular Dystrophy
Quantitative Muscle Ultrasound as a Marker of Progression in Children With Muscular Diseases
The aim of our study is to Assess skeletal muscle structural status in children with inflammatory myositis and Duchenne muscular dystrophy using musculoskeletal ultrasound and to perform a longitudinal follow up of these changes…
- Trial name
- NCT03786913
- Testing
- Quantitative muscle ultrasound measurements
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Benha University
Muscle Weakness
The Impact of Quantitative Neuromuscular Monitoring in the PACU on Residual Blockade and Postoperative Recovery
Neuromuscular blocking drugs (NMBDs) provide anesthesiologists with powerful intraoperative tools, but their use carries the potential risk of serious postoperative complications.
- Trial name
- NCT01933841
- Testing
- TOF-Watch SX, Notify the provider
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Vanderbilt University Medical Center
Myasthenia Gravis
Physical Activity Monitoring in Myasthenia Gravis
The goal of this observational study is to evaluate the feasibility of using wearable sensor and digital technologies to measure motor and speech function in adults with autoimmune Myasthenia Gravis (MG).
- Trial name
- NCT06277830
- Testing
- Wearable sensor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
ARDS, TTM
TwichView-guided Atricurium Dose Adjustment Trial
The goal of this clinical trial is to learn if using a monitor that measures muscle response can lower the amount of muscle relaxant medicine needed in adults who are treated in an intensive care unit (ICU) and need a continuous…
- Conditions
- ARDS, TTM, ECMO, Neuromuscular Blockade Monitoring
- Trial name
- NCT07807046
- Testing
- EMG-based quantitative TOF-guided atracurium titration
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Fu Jen Catholic University Hospital
Sugammadex
Quantitative Neuromuscular Monitoring and Gastric Bypass Surgery
This is a single site, prospective, non-blinded, non-randomized, before/after study. This study is designed to evaluate the impact of monitoring and reversal guidelines for neuromuscular blocking drugs on the post-operative…
- Trial name
- NCT05886218
- Testing
- Quantitative Neuromuscular Function Monitoring
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- University of California, Davis
Neuromuscular Blockade, Anesthesia
Sugammadex Dosing: Anaesthesiologist Clinical Perception Versus Quantitative Monitoring
Many clinicians continue to rely on subjective evaluation in making decisions about the adequacy of neuromuscular function before tracheal extubation rather than using quantitative monitoring.
- Conditions
- Neuromuscular Blockade, Anesthesia, TOF, Curarization, Postoperative Residual
- Trial name
- NCT04762420
- Testing
- Dose of sugammadex according to SSD and QSD
- Where
- Portugal
- Volunteers
- 66 people
- Sponsor
- Hospital do Divino Espírito Santo de Ponta Delgada
Neuromuscular Blockade, Muscle Relaxation
Clinical Application of "Train of Four" Testing in the Intraoperative Monitoring Setting
The study examines the clinical application of TOF (train of four test) used by anesthesiologists and neurophysiologists during instrumented spine procedures, as well as certain associated parameters.
- Trial name
- NCT01932983
- Testing
- Train of four test
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Neuromuscular Blockade
Median Versus Ulnar Nerve Quantitative Electromyography Neuromuscular Blockade Monitoring Comparison
Medications used to relax the muscles are used during surgery. The amount of muscle relaxation can monitored with devices that stimulate a specific nerve and evaluate the muscle response.
- Trial name
- NCT06553131
- Testing
- Neuromuscular Transmission Monitoring
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Loma Linda University
Observation of Neuromuscular Block
Train of Four Motor Point Stimulation and Monitoring
The assessment of neuromuscular blockage is common practice in the operating room, in which such agents are employed. Still today, the use of simple hand held stimulators and visual monitoring of these responses are the norm.
- Trial name
- NCT02591108
- Testing
- Neuromuscular Block Aid, Standard of Care: Microstim Plus
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Residual Paralysis, Post Anesthesia, Postoperative Complications
Predicting Neuromuscular Recovery in Surgical Patients Using Machine Learning
Despite emerging efforts to decrease residual paralysis and postoperative complications with the use of quantitative neuromuscular monitoring and reversal agents their incidences remain high.
- Conditions
- Residual Paralysis, Post Anesthesia, Postoperative Complications, Neuromuscular Blockade, Quantitative Neuromuscular Monitoring
- Trial name
- PINES (NCT05471882)
- Where
- 2 sites in Germany
- Volunteers
- 240,000 people
- Sponsor
- University Hospital Ulm