Clinical trials: Quantitative Sensory Testing
Chronic Pain, Child
Exercise as Medicine for Pediatric Chronic Pain
Youth with chronic pain struggle to go to school, play sports, or spend time with friends and family due to pain. Medications are often ineffective, and aerobic exercise may improve both pain sensitivity and participation in…
- Conditions
- Chronic Pain, Child, Adolescent
- Trial name
- NCT07182006
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Healthy
Vestibular Pain Interactions
The goal is to establish the practical usefulness of vestibular stimulation for modulating pain perception and to describe the possible mechanisms that could underlie neural vestibular-somatosensory interactions.
- Trial name
- VPI (NCT02358954)
- Testing
- Quantitative sensory testing, CHEPS, 3D Turntable
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sickle Cell Disease, Pain
Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Conditions
- Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing
- Trial name
- NCT06725550
- Testing
- needling acupuncture, laser acupuncture
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Healthy
The Effects of a Moderate Intensity Training Program Versus a High Intensity Training Program on Central Pain Processing
Previous studies have shown that healthy individuals who take more steps per day and who spend more time on moderate- to vigorous-intensity activities exhibit better pain inhibition and less pain facilitation.
- Trial name
- ChronicPA-PAIN (NCT06207422)
- Testing
- Moderate intensity training program, High intensity training program
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Ghent
Primary Headache Disorders, Tension Headache
Pericranial and General Sensitivity in Patients With Primary Headache
Primary headaches such as migraine and tension type headache are among the most common neurological disorders and frequently cause significant disability and reduced quality of life.
- Conditions
- Primary Headache Disorders, Tension Headache, Tension-type Headache, Migraine
- Trial name
- HEAD-TMD (NCT07514208)
- Testing
- Pericranial Tenderness Assessment, Pressure Pain Threshold Assessment, Temporomandibular Disorder Assessment
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Chronic Pancreatitis, Chronic Pain
Pancreatic Quantitative Sensory Testing (P-QST)
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Conditions
- Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
- Trial name
- NCT06996535
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy
Neural Contributions to Exercise-Induced Hypoalgesia With Blood Flow Restriction
This experimental study explores the neurophysiological mechanisms associated with pain modulation following a single session of low-intensity resistance exercise combined with BFR in healthy young adults.
- Trial name
- NCT07122011
- Testing
- Low-Intensity Resistance Training with BFR
- Where
- Argentina
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Healthy Subjects
The Influence of Baseline Sensitivity and Expectation on Exercise-induced Hypoalgesia in Young Healthy Adults
The purpose of this study is to investigate the influence of baseline experimental pain sensitivity and expectation on the pain response following a single exercise session.
- Trial name
- NCT03871504
- Testing
- Submaximal isometric exercise
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Marquette University
Complex Regional Pain Syndromes
Markers of Trajectory in Pediatric CRPS
Complex Regional Pain Syndrome (CRPS) is a severe and complex chronic pain condition in children. Many psychosocial factors impact its development and recovery.
- Trial name
- NCT03838107
- Testing
- observation and measure of trajectory of recovery in CRPS
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy
Effects of Urban Afforestation Activity on Pain Mechanisms
This single-group pretest-posttest clinical trial aims to evaluate the effects of a single-session afforestation activity on pain thresholds.
- Trial name
- NCT05364034
- Testing
- Urban Afforestation Intervention Program
- Where
- Spain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Healthy Volunteers Are Studied
Pain Sensitivity in Acute Inflammatory Pain
Pain is a complex experience influenced by gender and genetics, and, by psychosocial and sensory experiences. Pain sensitivity is thus highly variable between individuals.
- Trial name
- PASORI (NCT01345877)
- Testing
- first degree cutaneous burn injury
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Intellectual Disability
Characterization of Nociception Phenotype in Individuals With Intellectual Disability
Background: People with intellectual disability (ID) often have physical disabilities as well. These physical problems can affect their bones, muscles, nerves, and gastrointestinal tracts. All of these issues can also cause pain.
- Trial name
- NCT05473429
- Testing
- TSA2 Thermosensory Stimulator
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Pain Thresholds, Healthy Adult Participants
Evaluation of Psychophysical Responses After Mechanical Stimulation.
This study evaluates the test-retest reliability of psychophysical responses to non-injurious sharp stimuli applied via a robotic system.
- Trial name
- NCT07774429
- Testing
- Robot-controlled non-injurious mechanical stimulation
- Where
- Argentina
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Pain, Pain Management
Pain in Aging Former Athletes, Master's Athletes, and Nonathletes
The goal of this clinical trial is to determine how male and female former athletes experience pain and respond to moderate-intensity exercise (strength versus aerobic) compared with both current master's athletes and…
- Conditions
- Pain, Pain Management, Athlete, Exercise Training
- Trial name
- PAIN (NCT07502742)
- Testing
- Moderate-Intensity Strength Exercise Intervention, Moderate-Intensity Aerobic Exercise Intervention
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Marquette University
Neuropathic Pain, Radiculopathy, Cervical
Evaluation of Neuropathic Pain in the Context of Clinical Symptoms, Quantitative Sensory Tests and Imaging With FMRI
This study is planned to evaluate patients with upper extremity neuropathic pain due to cervical radiculopathy with clinical symptoms, Quantitative Sensory Testing(QST) and Functional Magnetic Resonance Imaging(fMRI).
- Trial name
- NCT03890315
- Testing
- Functional MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Peripheral Neuropathic Pain, Nociceptive Pain
Determine the Effect of AZD3161,Injected Intradermally, on Quantitative Sensory Testing Variables in Normal and Ultraviolet-C (UVC) Exposed Skin in Healthy Volunteers
The purpose of this study is to investigate the effect of AZD3161 on mechanical pain sensitivity and axon reflex flare in normal and ultraviolet C irradiated skin.
- Trial name
- NCT01240148
- Testing
- AZD3161, Lidocaine
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Axial Spondyloarthritis, Central Sensitisation
Investigation of Central Sensitization Frequency and Related Factors in Axial Spondyloarthritis Patients
The term axial spondyloarthritis (axSpA) describes a group of chronic inflammatory diseases that characterized with spinal involvement.
- Trial name
- NCT04485078
- Testing
- Pressure pain threshold, Temporal summation, Conditioned pain modulation
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Marmara University
Autism Spectrum Disorder (ASD), Pain Perception
Quantitative Sensory Testing to Study Pain Perception in Autism
This study aims at assess sensory perception, and pain perception, in neurodivergent children and adolescent in the autism spectrum.
- Trial name
- PPiA (NCT06659731)
- Testing
- Quantitative Sensory testing (QST), EEG
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Chronic Pancreatitis, Chronic Pain
QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Trial name
- NCT03434392
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Anna Evans Phillips