Clinical trials: RANDOMIZED
Estazolam-dependent Insomnia
A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia
Insomnia is a disorder characterized by difficulties in falling asleep, maintaining sleep or waking up too early, and impairment of daytime functioning.
- Trial name
- ESAAEDI (NCT06258226)
- Testing
- Conventional dosage reduction, Auricular acupressure
- Volunteers
- 108 people
- Sponsor
- Wenzhou Central Hospital
Depressive Disorder, Major
Open-Label, Randomized Study Evaluating Treatment With Venlafaxine Extended-Release Plus Dialogues Time to Talk Program
The purpose of this study is to evaluate the effect of the Dialogues Time to Talk program in subjects treated with Venlafaxine Extended Release (ER).
- Trial name
- NCT00401726
- Testing
- Venlafaxine ER, Dialogues Time to Talk Program
- Where
- 44 sites in United States
- Volunteers
- 537 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Ascites Hepatic
"Exploring the Potential Benefits of Using Dapagliflozin in Cirrhotic Chronic Liver Disease Patients- A Randomized Controlled Trial"
This study aims to evaluate beneficial effects of using dapagliflozin in cirrhotic chronic liver disease patients. We hypnotized that the use of dapagliflozin will be associated with fewer need for large volume paracentesis hence…
- Trial name
- NCT07684326
- Testing
- Dapagliflozin
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Beni-Suef University
Infant, Premature, Hypothermia, Newborn
Cardboard Cot in Neonatal Thermoregulation: A Randomized Cross Over Trial
This study will determine whether the efficacy of Mylar-lined cardboard cots is equivalent to traditional incubators in their ability to prevent hypothermia (axillary temperature < 36° C) in preterm neonates <36 6/7 weeks…
- Trial name
- CCot (NCT03344978)
- Testing
- Cardboard Cot Care, Incubator Care
- Sponsor
- University of Alabama at Birmingham
Colon Cancer, Rectal Cancer
Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors
This phase II, randomized pilot trial studies the effect of the consumption of foods made with resistant starch compared to foods made with corn starch on biomarkers that may be related to colorectal cancer progression in stage…
- Conditions
- Colon Cancer, Rectal Cancer, Cancer Survivor, Colorectal Adenocarcinoma
- Trial name
- NCT03781778
- Testing
- Dietary Intervention (resistant starch), Dietary Intervention (regular starch), Questionnaire Administration
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Fred Hutchinson Cancer Center
Physical Functional Performance, Psychological Health
Interactive Exergaming With Otago Exercise Program on Mobility in Community-Dwelling Older Adults
This clinical trial aims to evaluate the effectiveness of interactive exergaming combined with Otago Exercise Program on mobility among community-dwelling older adults aged 65 and above.
- Conditions
- Physical Functional Performance, Psychological Health, Physical Fitness, Mobility Limitation
- Trial name
- GAME-OEP (NCT06814678)
- Testing
- Interactive Exergaming with Otago Exercise Program, Control Group with Usual Care
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University
Behcet Syndrome
Zinc Supplementation and Behçet's Syndrome
To study the effects of zinc gluconate supplementation on patients with Behçet's syndrome, 50 patients will be randomly allocated to two groups: placebo group or zinc group (one tablet of 30 mg/day elemental zinc) for 12 weeks.
- Trial name
- NCT05098678
- Testing
- Zinc gluconate
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Tabriz University of Medical Sciences
Obsessive-Compulsive Disorder and Symptoms
Brief Anxiety Sensitivity Treatment for Obsessive Compulsive Symptoms
Obsessive-compulsive disorder (OCD), characterized by recurrent obsessions and/or compulsions, is a disabling psychiatric condition affecting approximately 2-3% of the population.
- Trial name
- COAST (NCT02635178)
- Testing
- Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Florida State University
Critical Illness
Efficiency of Continuous Glucose Monitoring in Critically Ill Patients
The purpose of this study is to determine whether, real-time continuous glucose monitoring in critically ill patients with intensive insulin therapy would increase the percentage of time of normoglycemia, defined as glucose…
- Trial name
- NCT00494078
- Testing
- Real-time glucose monitoring system (Guardian, Medtronic), intensive insulin therapy
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Heart Failure, Overweight and Obesity
Mobile Applet for Weight Management in Obese Heart Failure Patients
The objective of this clinical trial is to investigate the effect of weight reduction through a diet management application and an intelligent weight scale on a composite cardiovascular endpoint in obese patients with heart…
- Conditions
- Heart Failure, Overweight and Obesity, Weight Loss, Heart Failure With Reduced Ejection Fraction
- Trial name
- IDEAL-HF (NCT06455878)
- Testing
- Full usage of diet management app group and with the full usage of an intelligent weight scale, Limited usage of diet management app group and with the limited usage of an intelligent weight scale
- Where
- 26 sites in China
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Heart Health Research Center
Anxiety, Pain
Effect of the 4-7-8 Breathing Technique Before Central Venous Catheter Insertion
Purpose: This study aims to evaluate the effect of the 4-7-8 breathing technique applied before central venous catheter (CVC) insertion on patients' anxiety, pain, and vital signs.
- Conditions
- Anxiety, Pain, Vital Sign Evaluation, 4-7-8 Breathing Technique
- Trial name
- NCT07917585
- Testing
- 4-7-8 breathing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mersin University
Breast Cancer
A Clinical Study of Hetrombopag Olamine Tablets for Thrombocytopenia Induced by Anti-tumor Treatment in Advanced Breast Cancer
This study now plans to explore the efficacy and safety of hetrombopag in cancer therapy-induced thrombocytopenia in advanced breast cancer, so as to further guide the clinical application of hetrombopag in chemotherapy-induced…
- Trial name
- NCT05394285
- Testing
- Hetrombopag
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Henan Cancer Hospital
HIV/AIDS and Infections, Sexually Transmitted Diseases
Puerto Rico Cuidalos Parent-adolescent Program
Latino adolescents are at high risk for HIV/AIDS, other sexually transmitted infections (STIs), and unintended pregnancies. Puerto Rican adolescents, in particular, experience disparities in these areas, yet few adolescent and…
- Conditions
- HIV/AIDS and Infections, Sexually Transmitted Diseases, Pregnancy Prevention
- Trial name
- NCT03063385
- Testing
- Parental Communication intervention, Health promotion control condition
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Ischemia-reperfusion Injury, Kidney Transplant; Complications
A Trial to Assess Efficacy and Safety of ex Vivo Allograft Admin of iCM012 Solution 2 mg/ml to Improve Its Function in Recipients of DCD Kidneys
Randomized (1:1), placebo controlled, double blind efficacy trial. 200 patients will be followed up for 12 months post transplantation.
- Trial name
- NCT06582485
- Testing
- iCM012 solution 2 mg/mL
- Volunteers
- 200 people
- Sponsor
- iCoat Medical AB
Schizophrenia, Schizoaffective Disorder
Clozapine-Augmentation With Ziprasidone or Risperidone, a Randomized, Prospective Trial
We aim to compare the augmentation of clozapine with ziprasidone or risperidone in a randomized, prospective manner.
- Trial name
- NCT00224315
- Testing
- ziprasidone, risperidone
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Pregnancy Complications, Gestational Diabetes Mellitus in Pregnancy
The Effect of Early Screening and Intervention for Gestational Diabetes Mellitus on Pregnancy Outcomes
Context: Women with gestational diabetes have excessive fetus growth weeks earlier than the screening period recommended currently, suggesting that earlier screening and intervention may improve pregnancy outcomes and the health…
- Trial name
- TESGO (NCT03523143)
- Testing
- early screening and intervention, standard screening and intervention
- Where
- Taiwan
- Volunteers
- 967 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Orthopedic Disorder, Humerus Fracture
Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture
Proximal humerus fractures can be a debilitating injury in the elderly, impacting the ability to function independently or complete activities of daily living due to pain and restricted shoulder motion.
- Conditions
- Orthopedic Disorder, Humerus Fracture, Shoulder Arthroplasty, Reverse Shoulder Replacement
- Trial name
- NCT06869343
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Pulmonary Disease, Chronic Obstructive
A 24-week Study to Compare Umeclidinium/Vilanterol (UMEC/VI), UMEC and Salmeterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
COPD is characterized by an airflow limitation, which is not fully reversible, usually progressive and accompanied by chronic cough, sputum production and dyspnea, which can be a major cause of disability and anxiety associated…
- Trial name
- NCT03034915
- Testing
- UMEC/VI 62.5/25 mcg via ELLIPTA, UMEC 62.5 mcg via ELLIPTA, Salmeterol 50 mcg via DISKUS
- Where
- 212 sites in United States, Argentina and 10 more
- Volunteers
- 2,696 people
- Sponsor
- GlaxoSmithKline
Erosive Esophagitis
Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis
The purpose of this study is to demonstrate the efficacy of CJ-12420, once daily (QD), compared to esomeprazole in patients with erosive esophagitis classified as Los Angeles (LA) classification grades A to D at Week 8
- Trial name
- NCT02456935
- Testing
- CJ-12420 100 mg QD, Esomeprazole 40 mg QD
- Where
- South Korea
- Volunteers
- 280 people
- Sponsor
- HK inno.N Corporation
Bruxism, Manual Theapy
Effects of Manual Therapy and Home Exercise in Bruxism
Objectives: This trial aimed to examine the effects of manual therapy and home exercise treatments on pain, sleep quality, stress level and quality of life in patients with bruxism.
- Conditions
- Bruxism, Manual Theapy, Exercise, Orofacial Pain
- Trial name
- NCT06610435
- Testing
- Manual Therapy, Home Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara University
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