Clinical trials: RANDOMIZED
Diabetic Foot Ulcer, Type 2 Diabetes Mellitus With Complication
Implementation of a Preventive Diabetic Foot Care Program for Patients at Risk of Diabetic Foot
This study aims to evaluate the effect of a preventive diabetic foot care program on the knowledge, behavior, self-management, and glycemic control levels of type 2 diabetic patients at risk of diabetic foot.
- Trial name
- NCT06770829
- Testing
- DiaFOOTCare Program, Ministry of Health and Education
- Volunteers
- 78 people
- Sponsor
- Akdeniz University
Glaucoma
Randomized Controlled Trial on Visual Field Training
Unreliability and visual field variability is a known problem with automated perimetry in both developing and developed country settings.
- Trial name
- NCT01669031
- Testing
- Practice program
- Where
- Chile
- Volunteers
- 200 people
- Sponsor
- Oftalmologia Hospital Sotero del Rio
Hematologic Malignancies
Infection Rates of Myeloablative Allo SCT Recipients Receiving Neutropenic Diets Versus Non-Neutropenic Diets
In the transplant community, there is debate regarding the most appropriate food services for stem cell transplant patients. Recommendations regarding the use of low bacterial diets have been based on theoretical concepts of…
- Trial name
- NCT01687231
- Testing
- Non-neutropenic Diet
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Duke University
Tooth Extraction Site Healing, Ridge Augmentation
Safety and Performance, and Dose, of OsteoAdapt DE in Localized Alveolar Ridge Augmentations
This study's objective is to evaluate OsteoAdapt DE's safety and performance in comparison to Xenograft particulate bone graft for alveolar ridge augmentation.
- Conditions
- Tooth Extraction Site Healing, Ridge Augmentation, Bone Graft
- Trial name
- RESTORE (NCT07078331)
- Testing
- OsteoAdapt DE (0.8 mg), OsteoAdapt DE (2.0 mg), Xenograft Bone Graft
- Where
- 6 sites in Armenia, Israel
- Volunteers
- 45 people
- Sponsor
- Theradaptive, Inc
Dental Caries in Children
Different Methods for Reducing Buccal Infiltration Local Anesthesia Injection Pain
Local anesthetic injection is considered one of the most annoying dental procedures. The use of topical anesthesia is considered a routine procedure in the dental clinic especially for children.
- Trial name
- NCT06290531
- Testing
- Buzzy device (cold and vibration), Buzzy device (vibration only), precooling
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes
Diabetes-specific Formulas on Nutritional Outcomes in Individuals With Diabetes Who Require Nutritional Support
The study aims to demonstrate the non-inferiority of diabetes-specific formula (DSF)1 compared to DSF2 in individuals with type 1 diabetes, type 2 diabetes or prediabetes and who are at nutritional risk.
- Trial name
- NCT06632002
- Testing
- DSF1, DSF2, Standard of Care (SOC)
- Where
- Taiwan
- Volunteers
- 103 people
- Sponsor
- Abbott Nutrition
Respiratory Failure
Awake Prone Position to Reduce Ventilation Inhomogeneity in COVID-19 Acute Respiratory Failure
Evaluation of awake prone position on ventilation inhomogeneity in COVID-19 associated respiratory failure.
- Trial name
- ProneSpontCov (NCT04632602)
- Testing
- physiological effects of awake prone position in COVID 19 patients
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Development Delay
Effects of Family Work Shop for Children With Developmental Delays: a Randomized Trial
To identify the therapeutic effects of short-term family-centered work shop for children with developmental delays
- Trial name
- NCT03209453
- Testing
- family work shop
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Taipei Medical University
Cardiovascular Diseases, Cardiovascular Risk Factors
The Effect of a Digital Heart Health App and Lifestyle Intervention for Heart Disease in Primary Care.
Despite the availability of medications, many people around the world continue to live with long-term health problems like heart disease, stroke and diabetes. In Canada, heart disease is a leading cause of death.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factors, Dyslipidemia, Cholesterol
- Trial name
- CHEAP (NCT06919302)
- Testing
- Digital Heart Health Program
- Where
- Canada
- Volunteers
- 1,100 people
- Sponsor
- University of Toronto
Analgesia
Analgesia After Total Knee Arthroplasty
The recovery from knee replacement surgery often involves a significant amount of pain. The best way to prevent/treat this pain is unknown.
- Trial name
- NCT00869037
- Testing
- Periarticular Injection, CFNB + Posterior Capsular Injection
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Manitoba
ADHD
A Comparison of Group Cognitive Behavioural Therapy (CBT) and Structured Activity Group for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Many adults with attention deficit hyperactivity disorder (ADHD) experience difficulties with inattention, planning, impulsivity and emotion regulation that impacts work and social life negatively also after treatment with…
- Trial name
- NCT07834437
- Testing
- Group CBT based on DBT-skills training, Activity group
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Stockholm
Phthisis Bulbi
Comparison of Local Made and Imported Porous Polyethylene Orbital Implant for Enucleation in Thailand
This study wants to compare between two types of implants in enucleation. Both of them are made from porous polyethylene but have different fabricating techniques.
- Trial name
- NCT01312545
- Testing
- 3DP, Medpor
- Where
- Thailand
- Volunteers
- 105 people
- Sponsor
- Mettapracharak Hospital
Post-surgical Pain, Pain, Acute
Online Psychology Program for Chronic Pain After Surgery
This project will evaluate the feasibility of a new fully self-guided online Acceptance and Commitment Therapy (ACT) program entitled Advancing Online Psychology Tools for the Transitional Pain Service (ADOPT-TPS), developed on…
- Conditions
- Post-surgical Pain, Pain, Acute, Pain, Chronic, Post-Surgical Pain, Chronic
- Trial name
- ADOPT-TPS (NCT06455345)
- Testing
- Self-Guided Online ACT Program, Treatment As Usual
- Where
- 2 sites in Canada
- Volunteers
- 68 people
- Sponsor
- University Health Network, Toronto
Mechanical Ventilation
Tracheal Suctioning and Expiratory Pause in Bronchial Hygiene
A randomized crossover clinical trial conducted in an Intensive Care Unit of the Hospital de Clinicas de Porto Alegre (HCPA) to compare the efficacy of the two techniques on the amount of aspirated pulmonary secretion and…
- Trial name
- NCT05579145
- Testing
- 5-Second Expiratory Pause, 10-Second Expiratory Pause
- Where
- 2 sites in Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Gastrointestinal Health
Effects of Dietary Fiber on Gastrointestinal Function
The purpose of the study will be to assess the gastrointestinal effects of a dietary fiber in healthy, adult volunteers.
- Trial name
- NCT01495182
- Testing
- Dietary fiber
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ingredion Incorporated
Healthy Adult Subjects
A Study to Evaluate the Pharmacokinetics Similarity of CBP-201 in Healthy Adult Chinese Subjects
This is a single-center, randomized, open-label, single-dose, parallel-designed PK similarity study.
- Trial name
- NCT05917782
- Testing
- Test drug (T1): CBP-201 injection (pre-filled syringe, 150 mg/1 mL), Test drug (T2): CBP-201 injection (pre-filled syringe, 300 mg/2 mL), Reference drug (R): CBP-201 injection (vial, 150 mg/1 mL)
- Where
- China
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Connect Biopharm LLC
Healthy
Safety and Tolerability of STP206 in Healthy Adult Subjects
The study will assess the safety, tolerability and fecal shedding of STP206 when given as a single dose and when given as daily doses for one week.
- Trial name
- NCT00922324
- Testing
- STP206 or vehicle control
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Leadiant Biosciences, Inc.
Shoulder Impingement Syndrome
Exercise Application in the Treatment of Patients With Subacromial Pain Syndrome
This study evaluate the effectiveness of adding neuromuscular exercises with tactile, visual and auditory feedback to a scapula-focused treatment, both emphasizing the periscapular muscles on improvement of disability in patients…
- Trial name
- NCT02695524
- Testing
- Scapula-focused exercises, Motor control exercises
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Moderate to Severe Active Rheumatoid Arthritis
Phase III Clinical Trial Comparing the Safety, Efficacy, and Immunogenicity of Recombinant Anti-interleukin-6 Receptor Humanized Monoclonal Antibody Injection in Combination With Methotrexate and Jamelor ® in the Treatment of Moderate to Severe Rheumatoid Arthritis
This is a multi-center, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of intravenous HS628 in combination with MTX versus Actemra in combination with MTX, in participants with moderate to…
- Trial name
- NCT06048224
- Testing
- HS628+MTX, Actemra +MTX
- Where
- China
- Volunteers
- 669 people
- Sponsor
- Zhejiang Hisun Pharmaceutical Co. Ltd.
ADHD, Behavioral Disorder
Randomized Controlled Trial of the Myndlift BPT App
We propose addressing these aims by conducting a randomized controlled trial (RCT) that will evaluate the hybrid BPT (Myndlift BPT) compared to a wait-list control group.
- Trial name
- NCT05182424
- Testing
- Myndlift BPT App & As-Needed Therapist Support
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- New York University
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