Clinical trials: RCT
Mental Health, Anxiety
RCT for Latina Mental Health Using Web-Based Apps
This study compares a choice-driven, interactive, evidence-informed storytelling web-based app intervention with links to resources and treatment (Tx) recommendations (made by a character via her blog) and Tx locator, to a…
- Conditions
- Mental Health, Anxiety, Depression, Well-Being, Psychological
- Trial name
- NCT06874790
- Testing
- Catalina, Control webpage
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depression Disorders
Efficacy and Safety of tACS for Depression: a Multicenter RCT Study
Transcranial alternating current stimulation (tACS) is a promising non-invasive technique for major depression, because of its advantage of lower risks and expenses compared to other therapies such as deep brain stimulation…
- Trial name
- NCT06891326
- Testing
- active tACS
- Where
- 2 sites in China
- Volunteers
- 72 people
- Sponsor
- Ruijin Hospital
Malaria
Safety and Efficacy of Methylene Blue Combined With Amodiaquine or Artesunate for Malaria Treatment in Children of Burkina Faso
The purpose of the study is to investigate the safety and efficacy profile of a new paediatric MB formulation combined with AQ or AS and compared to AS-AQ in young African children with uncomplicated falciparum malaria.
- Trial name
- NCT00545935
- Testing
- Methylenblue-Amodiaquine (MB-AQ), Methylenblue-Artesunate (MB-AS), Artesunate-Amodiaquine (AS-AQ)
- Where
- Burkina Faso
- Volunteers
- 186 people
- Sponsor
- Heidelberg University
Rheumatoid Arthritis
Effectiveness of Occupational Therapy in Patients With Rheumatoid Arthritis(RCT)
The purpose of the study is to compare the short- and long-term effectiveness of an individualized, resource-oriented joint protection intervention with the standard, problem-oriented joint protection intervention for patients…
- Trial name
- NCT00400868
- Testing
- psycho-educational Joint protection education
- Where
- 4 sites in Switzerland
- Volunteers
- 54 people
- Sponsor
- University of Zurich
Irritable Bowel Syndrome
Acupuncture/Moxibustion for Irritable Bowel Syndrome (IBS)
The objective of this study is to test the efficacy of a symptom management treatment strategy, namely, Acupuncture/Moxibustion (Acu/Moxa) to improve the symptoms associated with Irritable Bowel Syndrome (IBS) in persons between…
- Trial name
- Acu/MoxaIBS (NCT00945074)
- Testing
- Standard Acupuncture/Moxibustion (fixed protocol), Individualized Acupuncture/Moxibustion
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- New York University
Evaluations, Diagnostic Self
Radiographic Evaluation of Bone Height Gain With Dental Implant Placed Simultaneously With Closed Sinus Lifting Using Hydraulic Lift Technique Versus Summers' Osteotome Technique in Posterior Edentulous Maxilla (RCT)
Radiographic evaluation of bone height gain with dental implant placed simultaneously with closed sinus lifting using hydraulic lift technique versus summers' osteotome technique in posterior edentulous maxilla (RCT)
- Trial name
- NCT04648514
- Testing
- Using of hydraulic lifter device for closed sinus lifting, patient satisfaction evaluation after using hydraulic lifter device
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Shoulder Impingement, Shoulder Arthritis
Pragmatic Posterior Capsular Stretch Versus Sleeper Stretch in Subject With Shoulder Pathologies
The glenohumeral joint is an articulation between the glenoid of the scapula and the head of the humerus that is enclosed by a synovial capsule divided into three main components: anterior, posterior, and the axillary pouch.
- Conditions
- Shoulder Impingement, Shoulder Arthritis, Shoulder Injuries, Shoulder Capsulitis
- Trial name
- NCT05064033
- Testing
- Pragmatic Set of intervention and posterior capsular stretch, Pragmatic Set of intervention and Sleeper Stretch
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Helping Hand Institute of Rehabilitation Sciences
Rotator Cuff Tears, Rheumatoid Arthritis Shoulder
Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study
The goal of the Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study is to collect safety and performance data on the commercially available Shoulder iD™ Primary Reversed Glenoid device.
- Conditions
- Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus
- Trial name
- SiD (NCT05868148)
- Testing
- Shoulder iD™ Primary Reversed Glenoid
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stryker Trauma and Extremities
Gastric Cancer, RCT
Perioperative Ivonescimab Plus S-1 and Oxaliplatin (SOX) for Locally Advanced Gastric or GEJ Adenocarcinoma
The purpose of this clinical trial is to evaluate whether perioperative ivonescimab in combination with S-1 and oxaliplatin (SOX) is effective in treating locally advanced gastric or gastroesophageal junction (GEJ)…
- Trial name
- Huaxi (NCT07374250)
- Testing
- Ivonescimab (20mg/kg Q3W), Oxaliplatin, S-1
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Sichuan University
Stroke, Ischemic, Aphasia
pBFS-guided cTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke
The objective of this trial is to evaluate the effectiveness and safeness of continuous Theta Burst Stimulation (cTBS) over the right Superior Temporal Gyrus (STG), guided by personalized Brain Function Sector (pBFS) technology…
- Trial name
- NCT05999318
- Testing
- active continuous Theta Burst Stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Changping Laboratory
Hypertension
H-Type Hypertension Precision Medicine Trial
This is a multicenter, randomized, double-blind, controlled clinical trial. It aims to investigate the effects of different doses of folic acid on lowering homocysteine (Hcy) in patients with hypertension with different genotypes…
- Trial name
- NCT03472508
- Testing
- Folic Acid, Enalapril Maleate and Folic Acid Tablets (Yiye), Enalapril
- Where
- 5 sites in China
- Volunteers
- 3,600 people
- Sponsor
- Shenzhen Ausa Pharmed Co.,Ltd
Hypertension, Prehypertension
UH3 Phase - Mindfulness-Based Blood Pressure Reduction (MB-BP) : Stage 2a RCT
The primary aim is to identify the impacts of a behavioral intervention called "Mindfulness-Based Blood Pressure Reduction" (MB-BP) vs.
- Trial name
- MB-BP (NCT03859076)
- Testing
- MB-BP, Enhanced Usual Care Control
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Brown University
Small Intestine Problem
Double/Single Balloon Enteroscopy Stiffening Wire RCT
This is a randomized clinical trial examining the use of a stiffening wire to increase depth of maximal insertion during double and single balloon enteroscopy.
- Trial name
- NCT02720848
- Testing
- Stiffening wire, Standard technique
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Arthroplasty, Replacement, Shoulder, Reverse Total Shoulder Arthroplasty
At Home, Digital Rehabilitation for Patients After Reverse Total Shoulder Arthroplasty
1. Why This Study Matters Over the past five years, more people in Korea have been having shoulder surgery. With our country moving into a super-aged society by 2025, these surgeries are expected to increase even more.
- Trial name
- DHI_RTSA (NCT06891378)
- Testing
- Intrevention group (mHealth group), control group (usual care)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Polycystic Ovary Syndrome, Diabetes, Gestational
Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome
Randomized, placebo controlled clinical trial that evaluate the role of taking metformin therapy during pregnancy in women with polycystic ovarian syndrome(PCOS) in reducing the development of gestational diabetes(GDM) and…
- Trial name
- MGDPCOS (NCT02802215)
- Testing
- metformin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Glaucoma, Neovascular, Vascular Endothelial Growth Factor Overexpression
Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT
To prospect studying the efficacy and safety of treating NVG with the intracameral versus the intravitreal injection of Bevacizumab.
- Trial name
- NCT03648814
- Testing
- Intracameral injection, Intravitreal injection
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Prince of Songkla University
Generalised Anxiety Disorder
Trial of Sertraline Versus Cognitive Behaviour Therapy for Generalised Anxiety
Generalised Anxiety Disorder (GAD) is common, causes unpleasant symptoms and impairs people's functioning. It is often chronic and may be accompanied by depression and other anxiety disorders.
- Trial name
- ToSCA (NCT02347033)
- Testing
- Sertraline, Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University College, London
Borderline Personality Disorder
Physical Activity in People With Borderline Personality Disorder (PABORD)
The aim of this Randomised Controlled Trial (RCT) is to test the effects of a structured physical activity (PA) program on symptoms in female outpatients aged 18 to 40 years with a diagnosis of Borderline Personality Disorder…
- Trial name
- PABORD (NCT06461104)
- Testing
- Structured Physical Activity Programme, Psychoeducational Programme
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Inflammatory Bowel Diseases, Ulcerative Colitis
Personalized B-fructan Diet in Inflammatory Bowel Disease Patients
This study aims to examine patient tolerability of personalized dietary fibre consumption recommendations (high-pectin diet versus high-B-fructan diet based on personalized responses), provided by an IBD dietician, based on our…
- Trial name
- NCT05615779
- Testing
- Randomized B-fructan diet, Personalized pectin diet, Personalized B-fructan diet
- Where
- 2 sites in Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Alcohol Use Disorder (AUD), Substance Use Disorders
The Anchor Study: Digitally Delivered Intervention for Reducing Problematic Substance Use
This study aims to validate W-SUDs as a digitally-delivered substance use disorder program through a fully-powered randomized control trial that will test the comparative efficacy of the mobile-app based substance use disorder…
- Trial name
- NCT04925570
- Testing
- W-SUDs, Digitally-delivered Psychoeducation
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Woebot Health
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