Clinical trials: RENAL INSUFFICIENCY, CHRONIC
Hyperparathyroidism, Secondary
Study to Assess the Impact on Calcium Levels When Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT) Switch From Cinacalcet to Etelcalcetide
This is a multicenter, multiple-dose, single-arm, open-label study to assess the impact on serum corrected calcium levels when switching patients from cinacalcet to etelcalcetide (AMG 416).
- Trial name
- NCT01932970
- Testing
- Etelcalcetide
- Where
- 40 sites in United States
- Volunteers
- 158 people
- Sponsor
- Amgen
End Stage Renal Disease, Renal Anemia
Assessment of an Anemia Model Predictive Controller for Anemia Management in Hemodialysis Patients
The purpose of this randomized, controlled pilot study is to evaluate the performance of this novel Anemia Controller (vis-à-vis standard of care) for anemia management in hemodialysis patients.
- Conditions
- End Stage Renal Disease, Renal Anemia, Chronic Kidney Diseases
- Trial name
- NCT04360902
- Testing
- Anemia Controller
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Renal Research Institute
Chronic Kidney Diseases
Assessment of Renal Vasculature and Function with Ferumoxytol-enhanced Magnetic Resonance Imaging
Conventional contrast-enhanced magnetic resonance imaging is typically performed with extracellular gadolinium chelates, which is often limited in patients with CKD owing to the risk of nephrogenic systemic fibrosis.
- Trial name
- NCT05045872
- Testing
- domestic polysaccharide superparamagnetic iron oxide nanoparticle
- Where
- China
- Volunteers
- 44 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Chronic Kidney Diseases
Comparison of Different Gfr Measurements in Chronic Kidney Diseases
Comparison of different Gfr measurements in Chronic Kidney Diseases
- Trial name
- NCT05696028
- Testing
- Gamma counter
- Volunteers
- 166 people
- Sponsor
- Assiut University
CKD, Chronic Kidney Diseases
Pregnancy and Contraception Education in Chronic Kidney Disease (PACE-CKD)
This pilot study will assess the efficacy of a pregnancy and contraception education decision aid (DA) for patients with chronic kidney disease to support decisions about reproductive health, and will assess feasibility and…
- Trial name
- PACE-CKD (NCT06189807)
- Testing
- Decision aid, Standard handout
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Michigan
Fatigue, End Stage Renal Disease
Fatigue in Chronic Haemodialysis Patients: an Experience Sampling Method Study
To investigate the course and diurnal change of fatigue symptoms and haemodialysis related symptoms in chronic haemodialysis patients, its relation to haemodialysis treatment and the association with other factors by implementing…
- Trial name
- FatHoM (NCT04049773)
- Testing
- haemodialysis
- Where
- 2 sites in Netherlands
- Volunteers
- 42 people
- Sponsor
- Zuyderland Medisch Centrum
Diabetes Mellitus, Type 2, Chronic Renal Insufficiency
An Investigational Drug in Patients With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (0431-028)(COMPLETED)
The purpose of this study is to determine the safety and tolerability of an investigational drug in patients with Type 2 Diabetes Mellitus (a specific type of diabetes) and Chronic Renal Insufficiency (inadequate kidney function).
- Trial name
- NCT00095056
- Testing
- sitagliptin, glipizide
- Volunteers
- 91 people
- Sponsor
- Merck Sharp & Dohme LLC
End Stage Chronic Renal Failure, Myofacial Pain
The Herbal Acupoint Patch for Dialysis Patient With Fistula-related Pain
To evaluate the effect of a traditional Chinese medicine (TCM) intervention on pain relief, mood and quality of life (QOL) in hemodialytic patients at a dialysis center in Southern Taiwan.
- Trial name
- Fistula Pain (NCT07380581)
- Testing
- Artemisias-ginger patch (AGP)
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Kidney Diseases, Peritoneal Dialysis
Effects of Curcumin Supplementation in Patients With Chronic Kidney Disease on Peritoneal Dialysis
The objective of this study is to assess whether supplementation with curcumin could modulate the intestinal microbiota, reducing levels of inflammatory markers of oxidative stress, uremic toxins and inflammasome, in patients…
- Conditions
- Chronic Kidney Diseases, Peritoneal Dialysis, Hemodialysis
- Trial name
- NCT04413266
- Testing
- Curcumin supplementation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Hypertension, Diabetes Mellitus, Type 2
ENCOMPASS: Expansion Study C
Some patients living with multiple long-term health conditions have difficulty accessing the services they need, despite available primary care and community resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- NCT04791267
- Testing
- Community Health Navigator Program
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- University of Calgary
Kidney Failure, Acute, Kidney Failure, Chronic
Ultrasound for Guidewire Detection
The aim of the project is to check if there is a possibility for a nephrologist to visualise the guidewire by means of available ultrasound scanners.
- Trial name
- NCT03727581
- Testing
- Ultrasound guidance
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Wroclaw Medical University
Kidney Failure, Chronic, Coronary Artery Disease
Prophylactic Effect of Nifedipine on Further Decline in Renal Function in Patients Undergoing Open-Heart Surgery
To compare renal function (51Cr-EDTA clearance) 48 hours post open-heart surgery (coronary bypass or valve surgery) in patients with impaired renal function after randomization to either nifedipine infusion at start of surgery…
- Trial name
- NCT00244530
- Testing
- Nifedipine
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- University of Oslo School of Pharmacy
Hemodialysis, Chronic Kidney Disease
The Effect of Mindfulness-Based Nursing Interventions Applied to Hemodialysis Patients on Psychological Well-Being and Treatment Adherence
Chronic kidney disease (CKD) and its treatment with hemodialysis pose significant challenges to patients' psychological well-being and adherence to complex treatment regimens.
- Trial name
- Mindfulness (NCT07471828)
- Testing
- The intervention group received mindfulness-based nursing interventions for six weeks
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Baskent University
Chronic Kidney Disease, Frailty
Effect of Synchronized Transcutaneous Electrical Diaphragm Stimulation Using Surged Faradic Current Combined With Inspiratory Muscle Training on Diaphragm Function and Clinical Outcomes in Patients With COPD
Chronic kidney disease (CKD) is a progressive condition that can be associated with reduced physical capacity, muscle weakness, fatigue, respiratory impairment and frailty.
- Trial name
- COPD TEDS (NCT07803900)
- Testing
- Transcutaneous electrical diaphragm stimulation (TEDS), Inspiratory muscle training (IMT)
- Where
- India
- Volunteers
- 42 people
- Sponsor
- Maharashtra University of Health Sciences
Kidney Failure, Chronic
A Study of Obinutuzumab to Evaluate Safety and Tolerability in Hypersensitized Adult Participants With End Stage Renal Disease Awaiting Transplantation
This is a Phase Ib, open-label study of single and repeat doses of obinutuzumab administered as intravenous (IV) infusion in adults with end stage renal disease (ESRD).
- Trial name
- NCT02586051
- Testing
- Obinutuzumab, Intravenous Immunoglobulin
- Where
- 9 sites in United States
- Volunteers
- 24 people
- Sponsor
- Hoffmann-La Roche
Chronic Kidney Disease With and Without Hemodialysis
Patterns of Cardiac Arrhythmia in Patients With Chronic Kidney Disease
Cardiovascular diseases remain the primary leading cause of death in patients on maintenance hemodialysis accounting for nearly 41% of deaths.
- Trial name
- Arrhythmia (NCT07640919)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Chronic Kidney Diseases
Pragmatic Trial of Messaging to Providers About Treatment of Chronic Kidney Disease
This study is a cluster-randomized clinical trial to evaluate whether a tailored, user-centered, clinical decision support (CDS) tool can positively influence prescriber behavior and increase prescription of guideline-directed…
- Trial name
- PROMPT-CKD (NCT07430930)
- Testing
- Best practice alert and order set for CKD
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Yale University
Chronic Kidney Disease Requiring Chronic Dialysis, Chronic Kidney Diseases
Cardiopulmonary Exercise Testing Parameters' Variability in Hemodialysis Patients.
Chronic kidney disease (CKD), especially end-stage kidney disease (ESKD), is associated with increased risk for cardiovascular events and all-cause mortality.
- Trial name
- NCT05557929
- Where
- Greece
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
End-Stage Kidney Disease, Hemodialysis
Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients
This is a prospective, randomized, double-blind, parallel group trial to assess the efficacy and safety of intravenous dextrose 5% solution compare with normal saline (standard care) in wash back procedure during haemodialysis in…
- Trial name
- NSD5 (NCT02590081)
- Testing
- Dextrose 5%, normal saline
- Where
- 15 sites in Malaysia
- Volunteers
- 434 people
- Sponsor
- Penang Hospital, Malaysia
Cognitive Impairment, End Stage Renal Disease
A Study to Assess the Tolerability and Efficacy of AKST1210 in Patients on Hemodialysis With Cognitive Impairment
This study will evaluate the tolerability, feasibility, and efficacy of the AKST1210 column in subjects with end-stage renal disease with cognitive impairment (ESRD-CI) undergoing hemodialysis 3 times per week.
- Trial name
- NCT04527328
- Testing
- AKST1210, Hemodialysis
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Alkahest, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.