Clinical trials: Radiation Caries
Diabetes Mellitus, Sarcoidosis
Salivary Proteins in Disease and Health
This study will examine saliva samples from healthy volunteers and patients with various diseases to learn more about how disease affects the mouth and salivary glands.
- Conditions
- Diabetes Mellitus, Sarcoidosis, Dental Caries, Sjorgren's Syndrome
- Trial name
- NCT00100204
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Caries,Dental, Head and Neck Cancer
Prevention of Caries in Head and Neck Cancer Survivors Who Underwent Radiotherapy
One of the long-term side effects of head and neck radiotherapy (RT) is radiation-induced tooth decay. Hyposalivation, associated with radiation therapy, further increases caries susceptibility and caries progression, due to the…
- Conditions
- Caries,Dental, Head and Neck Cancer, Radiotherapy; Complications
- Trial name
- RADIOCARIES (NCT06308796)
- Testing
- Application of CaP dental mousse
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Milan
Secondary Dental Caries
Assessment of Bioactive Bulk Fill Composite Versus High Viscosity Glass Ionomer Restorations for Carious Lesions
This trial will be conducted to compare the clinical performance between a new bioactive resin composite material and high viscosity glass ionomer for restoring occlusal carious lesions of posterior teeth in patients scheduled…
- Trial name
- NCT05332041
- Testing
- Predicta Bioactive bulk fil composite restoration
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Health, Dental Caries
The Use of Artificial Intelligence in the Dental X-rays Analysis
This cross-sectional study aims to perform a population-based assessment of the incidence of decay, dental fillings, root canal fillings, endodontic lesions, implants, implant and dental abutment crowns, pontic crowns, and…
- Conditions
- Oral Health, Dental Caries, Periapical Diseases, Tooth Loss
- Trial name
- NCT06258798
- Testing
- Taking a dental X-ray
- Where
- Poland
- Volunteers
- 1,025 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Head and Neck Cancer, Caries, Dental
Post-radiation Dental Disease Amongst Head and Neck Cancer Patients
Background Post-radiotherapy head and neck cancer (HANC) patients are at increased risk of dental caries and periodontal disease due to radiation-related damage to the teeth and salivary glands.
- Conditions
- Head and Neck Cancer, Caries, Dental, Periodontal Diseases, Radiotherapy Side Effect
- Trial name
- NCT03703648
- Testing
- Radiotherapy (curative) for head and neck cancer
- Where
- United Kingdom
- Volunteers
- 215 people
- Sponsor
- Belfast Health and Social Care Trust
Incipient Interproximal Caries
Can SAP P11-4 Affect The Appearance of Interproximal Cavities on an X-ray in a Military Population
The primary objective of the protocol is to learn about how SAP P 11-4 (produced commercially as Curodont products) can be used in a military population to treat incipient dental caries, or developing cavities that are still…
- Trial name
- NCT07829328
- Testing
- 0.05% Sodium Fluoride with Self-Assembling Peptides
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tripler Army Medical Center
Caries Assessment, Caries; Dentin
Evaluation of Radiation-Free Caries Detection Integrated Into Intraoral Scanners Compared With Conventional Diagnostic Methods
The goal of this study is to evaluate if an intraoral scanning device with an integrated radiation-free caries detection tool (near-infrared light) can detect early tooth decay.
- Conditions
- Caries Assessment, Caries; Dentin, Caries; Initial
- Trial name
- NCT07342595
- Testing
- intraoral scan with integrated caries detection tool
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Albert Mehl
Dental Caries
Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study
A comparison of caries detection rates between conventional intraoral bitewing radiography and a stationary intraoral digital tomosynthesis (s-IOT) using a carbon nanotube X-ray source array.
- Trial name
- NCT02873585
- Testing
- Stationary intraoral tomosynthesis, Standard conventional bitewing radiography
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dental Diseases
Intensive Preventative Dental Program Pilot Study
Radiation therapy to treat cancer may cause a dry mouth from damage to salivary glands which may increase the risk of cavities on the teeth.
- Trial name
- IPDP (NCT07218068)
- Testing
- Fluoride varnish, Regular Care, Medical Oncology Care Team
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Dental Caries
SDF Application in Oral Cancer Patients to Prevent Dental Caries
The Texas A \& M College of Dentistry, with partner Texas Oncology-Baylor Charles A. Sammons Cancer-Center Radiation-Oncology, proposes to conduct a preliminary clinical study (NIH Stage 0) to pilot test a randomized clinical…
- Trial name
- NCT05403125
- Testing
- silver diamine fluoride, 38%, Sodium fluoride gel, 5000 PPM
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Texas A & M University Baylor College Of Dentistry
Head & Neck Cancer, Head & Neck Squamous Cell Carcinoma
Longitudinal Oral Health Changes After Head and Neck Radiotherapy
This prospective observational study evaluates how head and neck radiotherapy affects oral health over time. Patients with head and neck cancer undergoing standard radiotherapy are followed from before treatment through multiple…
- Conditions
- Head & Neck Cancer, Head & Neck Squamous Cell Carcinoma, Periodontal Disease, Xerostomia
- Trial name
- HN-ORAL-RT (NCT07394842)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Head and Neck Cancer, Radiotherapy Side Effect
The Characterisation of RT Caries.
Overcoming limitations of previous studies, the following research project will assess the most significant acute and long-term complications of RT that affect HNC patients: oral mucositis, dry mouth feeling, taste alteration and…
- Trial name
- NCT03397823
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- King's College London
Caries,Dental
Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars
Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries…
- Trial name
- NCT06826456
- Testing
- sub-ablative Er,Cr:YSGG laser, Fluoride varnish application
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Sodium Fluoride
The Effect of Sodium Fluoride Application on the Prevention of Radiation Caries in NPC Patients
To evaluate the efficacy of sodium fluoride to preventing radiation caries for patients with nasopharyngeal carcinoma receiving radiotherapy.
- Trial name
- NCT06174012
- Testing
- Sodium Fluoride
- Volunteers
- 135 people
- Sponsor
- Sun Yat-sen University
Pulpitis - Irreversible, Caries
Endodontic-Restorative Pre-Radiation Therapy of Head and Neck Cancer Patients
Pilot study involving 20 patients undergoing dental treatment prior to radiation therapy. Comparison of outcome parameters to existing data of age and gender matched patients.
- Conditions
- Pulpitis - Irreversible, Caries, Head and Neck Cancer
- Trial name
- EndoRest (NCT04996641)
- Testing
- Root canal treatment and crown
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Dental Caries, Oral Cavity Cancer
Impact of Compliance With Fluoride Use on Caries Incidence After Cancer Therapy
Approximately 40 people will participate in this study. This study will compare two different methods of fluoride application. Both methods are currently used in dental practice and both have been shown to be effective.
- Conditions
- Dental Caries, Oral Cavity Cancer, Oral Complications of Chemotherapy and Head/Neck Radiation
- Trial name
- NCT03267914
- Testing
- Tray, Brush
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- A.T. Still University of Health Sciences
Radiation Caries
Nano-Silver Versus Bioactive Glass for Primary Teeth Exposed to Therapeutic Radiation
This study aims to evaluate and compare the remineralizing and antimicrobial effects of nano silver fluoride and bioactive glass gel on primary teeth exposed to therapeutic radiation.
- Trial name
- NCT07866482
- Testing
- Nano Silver Fluoride, Bioactive Glass Gel
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Faculty of Dental Medicine for Girls
Head and Neck Cancer
Chlorhexidine Gel Therapy for Cariogenic Oral Microflora
The goal of this clinical research study is to find out if 1% chlorhexidine gluconate gel will decrease the amount of bacteria that causes tooth decay. Whether the gel is acceptable to patients will also be studied.
- Trial name
- NCT01036412
- Testing
- 1% Chlorhexidine Gluconate Gel, Surveys
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center