Clinical trials: Radiation Dermatitis
Breast Cancer Female
Dermatitis During Adjuvant Irradiation for BREAst Cancer:
In the randomized DAI-BREAC trial, a reminder app will be prospectively tested that reminds breast cancer patients four times each day to perform the required skin care.
- Trial name
- DAI-BREAC (NCT06483477)
- Testing
- Standard skin care, Reminder App
- Where
- 5 sites in Denmark, Germany
- Volunteers
- 268 people
- Sponsor
- University Hospital Schleswig-Holstein
Breast Cancer
Curcumin for the Prevention of Radiation-induced Dermatitis in Breast Cancer Patients
Ionizing radiation is a toxic agent and widely accepted form of treatment for various types of cancer. Despite advances in medical technology, radiation therapy still causes severe early and late skin effects.
- Trial name
- NCT01042938
- Testing
- Curcumin C3 Complex
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Rochester
Head and Neck Cancer
Reducing Skin Side Effects in Patients Receiving Radiation on Tomotherapy
Radiation dermatitis is a common side effect in head and neck cancer (HNC) patients receiving radiotherapy, especially with advanced techniques like TomoTherapy.
- Trial name
- MCTPUT (NCT07357506)
- Testing
- Fragrance-Free Emollient (Glycerol-Based); A fragrance-free, glycerol-based emollient applied to the skin from day 1 of TomoTherapy., Mepitel Film (Silicone-Based Semi-Permeable Barrier Film)
- Volunteers
- 104 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Breast Cancer
Phase III Trial Evaluating Radium Bromatum Homeopathic Treatment Efficacy on Radiodermatitis Prevention and Treatment for Breast Cancer Women
Breast cancer is the second most frequent cancer worldwide. Principal therapy consists in radiotherapy, but this technic has sides effects as radiodermatitis, concerning about 90 percent of women treated.
- Trial name
- HOMEORAD (NCT03753776)
- Testing
- Radium bromatum pills, Radium bromatum/Apis mellifica/Belladonna pills
- Where
- France
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Radiodermatitis; Acute, Radiotherapy Side Effect
The Use of Photobiomodulation in the Management of Radiodermatitis in Patients in Palliative Care. A Prospective Study.
It is estimated that there will be 670,000 new cases of cancer worldwide in 2020-2022 and it is known that the most commonly instituted treatments in cancer are chemotherapy, radiotherapy and surgery.
- Conditions
- Radiodermatitis; Acute, Radiotherapy Side Effect, Cancer Patients, Palliative Care
- Trial name
- NCT05561803
- Testing
- Photobiomodulation Therapy
- Where
- Brazil
- Sponsor
- University of Nove de Julho
Radiodermatitis, Breast Neoplasms
Patient Reported Outcomes Using Mepitel Film During Radiotherapy
Breast cancer patients in post-operative radiotherapy (RT) often experience acute skin reactions like erythema, pain, itching and oversensitivity.
- Conditions
- Radiodermatitis, Breast Neoplasms, Side Effect
- Trial name
- NCT06133218
- Testing
- Mepitel Film
- Volunteers
- 101 people
- Sponsor
- Odense University Hospital
Breast Cancer, Radiation Dermatitis
Clinical Investigation on the Treatment of Radiation Induced Dermatitis With FR-101 Chest Dressing
Breast cancer is the top one incidence of cancer in women. Whole breast radiation therapy plays an indispensable role in the course of breast cancer treatment, and the radiation dermatitis is the major side effect affected…
- Trial name
- NCT06040983
- Testing
- FR-101 Chest Dressing
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Radiation Dermatitis Acute, Radiation Dermatitis
Oral or Topical Catechins for Radiation Dermatitis
Introduction Radiation-induced dermatitis (RID), which includes both acute and chronic forms, affects up to 95% of patients undergoing radiation therapy.
- Conditions
- Radiation Dermatitis Acute, Radiation Dermatitis, Fibrosis; Skin
- Trial name
- OCTOPUS-RD (NCT07149506)
- Testing
- Epicatechin, Epigallocatechin Gallate (EGCG), Saline (0.9% NaCl)
- Where
- Mexico
- Volunteers
- 162 people
- Sponsor
- CARLOS FRANCISCO SAAVEDRA GARCIA
Nasopharyngeal Neoplasms, Radiodermatitis
Comparison of Efficacy and Safety Between Medical Radiation Protectants (FORRAD®) and Trolamine (Biafine) for the Management of Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma Receiving IMRT
Radiation therapy remains the principal treatment for nasopharyngeal carcinoma (NPC). Although intensity modulated radiation therapy (IMRT) has been widely used in China nowadays, radiation dermatitis is still common.
- Trial name
- NCT02729324
- Testing
- Medical Radiation Protectants (FORRAD®), Trolamine (Biafine)
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Yun-fei Xia
Breast Cancer, Dermatitis
Barrier Film vs. Standard Skin Care in Preventing Dermatitis in Women With Breast Cancer Receiving Radiation
To evaluate the effectiveness of preventing Grade II or greater radiation dermatitis induced by adjuvant radiation therapy in women with breast cancer.
- Trial name
- NCT01762020
- Testing
- 3M Cavilon No Sting Barrier Film, Standard Preparation
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Epigallocatechin Gallate, Radio Dermatitis
Study of Topically Applied Green Tea Extract for Radio Dermatitis and Radiation Mucositis
Radiodermatitis and radiation mucositis were the most frequent side-effect during the course of radiotherapy, especially when concurrent chemoradiotherapy applied.
- Conditions
- Epigallocatechin Gallate, Radio Dermatitis, Radiation Mucositis
- Trial name
- NCT01481818
- Testing
- EGCG
- Volunteers
- 15 people
- Sponsor
- Shandong Cancer Hospital and Institute
Head and Neck Cancer, Breast Cancer
Neoviderm Skin Emulsion in the Prevention of Radiation Dermatitis
The purpose of this study is to determine whether NeoVIDERM is effective at preventing radiation dermatitis in patients receiving external beam radiation therapy to the head and neck or breast areas.
- Trial name
- NCT01701466
- Testing
- Aveeno cream, Flamazine cream, NeoVIDERM cream
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Radiation Dermatitis, Breast Cancer
Effect of a Mushroom Extract-Containing Topical Cosmetic Formulation During Breast Radiotherapy
This study evaluated a mushroom extract-containing topical cosmetic formulation for skin care in women receiving radiotherapy to the breast after breast-conserving surgery.
- Trial name
- NCT07755553
- Testing
- Mushroom extract-containing topical cosmetic formulation, Usual moisturizing cosmetic care
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hifas da Terra S.L.
Early Radiation Dermatitis
Mometasone Furoate Cream Reduces Acute Radiation Dermatitis in Head and Neck Squamous Cell Carcinomas' Patients
Radiation dermatitis is an acute effect of radiation therapy,Especially in the neck skin of head and neck squamous cell carcinomas' patients.The investigators wanted to confirm the benefit of mometasone furoate (MF) in preventing…
- Trial name
- NCT02495064
- Testing
- Mometasone Furoate Cream
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Yao Liao
Breast Cancer, Radiation Dermatitis
Efficacy Study With StrataXRT for the Prophylaxis of Radiation Dermatitis in Adjuvant Breast Radiation Treatment in Large Breasted Women Using a Prone Technique
For breast cancer patients undergoing adjuvant radiotherapy, radiation dermatitis (RD) is a common occurrence that can negatively impact patients' quality of life (QOL).
- Trial name
- NCT06865131
- Testing
- StrataXRT
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Radiation Dermatitis
Feasibility in the Prophylaxis of Radiation Dermatitis Severity
To compare radiation dermatitis severity in irradiated skin protected by an agent verses uncovered skin based on photographs and track patient reported outcomes with use of the agent.
- Trial name
- NCT04715386
- Testing
- StrataXRT
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Mayo Clinic
Breast Neoplasms, Dermatitis
Study of Epigallocatechin-3-gallate (EGCG) for Skin Prevention in Patients With Breast Cancer Receiving Adjuvant Radiotherapy
The investigators conduct this phase II study of EGCG therapy protection of the skin from damage induced by radiotherapy in breast cancer.
- Conditions
- Breast Neoplasms, Dermatitis, Prevention & Control, Epigallocatechin Gallate
- Trial name
- NCT02580279
- Testing
- EGCG
- Volunteers
- 68 people
- Sponsor
- Shandong Cancer Hospital and Institute
Alopecia, Radiodermatitis
Exploratory Study of Norepinephrine to Prevent Alopecia in Head and Neck Cancer Patients Treated With Radiotherapy
The study will evaluate the safety of topical norepinephrine in head and neck cancer patients who are receiving treatment with intensity modulated radiotherapy (IMRT).
- Trial name
- NCT01367990
- Testing
- Norepinephrine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- ProCertus BioPharm, Inc
Dermatitis, Healthy
Induction of Suction Blisters in Patients With Urticaria, Blistering Diseases, Inflammatory Dermatoses and Neoplastic Disorders, and in Normal Volunteers
The use of a suction blister apparatus has facilitated study of the immunologic capacity of human epidermal cells. We have been able to prepare purified populations of these cells after blister formation.
- Conditions
- Dermatitis, Healthy, Neoplasm, Urticaria
- Trial name
- NCT00001150
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
Determining Molecular Drivers of Radiation Dermatitis
This study is being conducted to address key gaps in current knowledge and set the stage for rational design of strategies to prevent (pre-exposure to radiation), mitigate (post-exposure to radiation before overt signs/symptoms…
- Trial name
- NCT04764682
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic