Clinical trials: Radiation Dermatitis Acute
Dermatitis, Radiation Induced
Efficacy of Pulsed Electromagnetic Field Therapy on Acute Radiodermatitis in Breast Cancer Patients
This study aims to evaluate the impact of PEMF on acute radiodermatitis in breast cancer patient and post mastectomy patients.
- Trial name
- NCT06003764
- Testing
- Pulsed electromagnetic field, traditional skin care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ahram Canadian University
Radiation Dermatitis
Adapalene Gel for Acute Radiation-Induced Skin Injury
his study aims to evaluate whether adapalene gel is effective and safe for treating acute radiation-induced skin injury in adults receiving radiotherapy.
- Trial name
- YNSZLYY-RADGEL (NCT07886320)
- Testing
- Adapalene gel 0.1%, Biafine topical emulsion
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yunnan Cancer Hospital
Radiation Induced Oral Mucositis, Radiodermatitis
Taurine's Therapeutic Effect on Acute Radiation-induced Oral Mucositis and Dermatitis
This is a single-center, double-blind, randomized controlled study. The patients were divided into control group and experimental group, 80 cases each.
- Trial name
- NCT07029178
- Testing
- Taurine granule
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Radiodermatitis; Acute
Use of Topical Olive Oil Cream for Prophylaxis Against Acute Radiodermatitis in Breast Cancer Patients
This study aims to compare the prophylactic effect of topical betamethasone valerate cream and topical olive oil cream in the prevention of acute radiation dermatitis (ARD) in breast cancer patients treated with radiation.
- Trial name
- NCT05285943
- Testing
- Olive oil cream, Betamethasone Valerate Cream, Base Cream
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Cairo University
Radiation Dermatitis
M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis
The purpose of this research study is to test the ability of a mobile device application (MyCap) to collect patient information about their radiation skin rash in patients with head and neck cancer being treated with radiation…
- Trial name
- NCT06441266
- Testing
- KeraStat cream, M-PART Assessments via MyCap, Clinical Assessments
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Wake Forest University Health Sciences
Nasopharangeal Cancer
Topical Chlorhexidine Spray for the Prevention of Acute Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma:
This study investigated the effects of topical chlorhexidine spray on the incidence, severity, and quality of life during radiotherapy in nasopharyngeal carcinoma patients.
- Trial name
- NCT07559877
- Testing
- 2% chlorhexidine, Sterile Water as control
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Acute Radiation Dermatitis, Head and Neck Cancer (H&N)
Effectiveness of 0.9% Normal Saline Soaking in Managing Acute Radiation Dermatitis
The goal of this clinical trial is to learn if normal saline soaks can reduce the severity of acute radiation dermatitis in patients with sarcomas or head and neck cancer receiving radiotherapy.
- Conditions
- Acute Radiation Dermatitis, Head and Neck Cancer (H&N), Sarcomas
- Trial name
- NCT07553260
- Testing
- Normal Saline Soaks (0.9% Sodium Chloride)
- Where
- Jordan
- Volunteers
- 150 people
- Sponsor
- King Hussein Cancer Center
Head and Neck Cancer, Radiation Dermatitis Acute
Using Silverlon® for Head and Neck Patients With Tracheostomies
The purpose of this study is to determine if prophylactic silver-nylon burn dressing Silverlon® prevents a severe skin reaction under tracheostomy collars.
- Conditions
- Head and Neck Cancer, Radiation Dermatitis Acute, Radiation Treatment
- Trial name
- NCT07856732
- Testing
- Silverlon®
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- State University of New York - Upstate Medical University
Radiodermatitis, Breast Cancer
Photobiomodulation Therapy for the Prevention of Acute Radiodermatitis in Breast Cancer Patients Undergoing Radiotherapy
Radiodermatitis (RD), an inflammatory skin reaction, occurs in more than 90 percent of cancer patients treated with radiotherapy (RT). This is the result of the radiation causing damage to the epidermal basal skin stem cells.
- Trial name
- LABRA (NCT03924011)
- Testing
- Photobiomodulation therapy (PBMT)
- Where
- 2 sites in Belgium
- Volunteers
- 71 people
- Sponsor
- Hasselt University
Head and Neck Cancers, Acute Radiation Dermatitis
StrataXRT vs Standard Clinical Practice for the Prevention of Acute Dermatitis in Head and Neck Cancers Patients
This is a phase IV, prospective, double-blind, randomized controlled trial with 2 study arms. The study population will be patients receiving chemoradiation for head and neck carcinomas, the majority of whom will be outpatients…
- Trial name
- NCT03394417
- Testing
- StrataXRT
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Acute Radiation Dermatitis, Traditional Chinese Medicine (TCM)
Efficacy and Safety of Qibei Jiedu Formula for Preventing and Managing Acute Radiation Dermatitis in Breast Cancer Patients
1. To evaluate the preventive and therapeutic effects of Qibei Jiedu Formula on acute radiation dermatitis in breast cancer patients, including the incidence of grade 2 or higher radiation dermatitis, wound healing time, and…
- Conditions
- Acute Radiation Dermatitis, Traditional Chinese Medicine (TCM), Breast Cancer
- Trial name
- NCT07380230
- Testing
- Standard Basic Treatment Combined with Qibei Jiedu Formula, Standard Basic Treatment Combined with Qibei Jiedu Formula simulator
- Where
- China
- Volunteers
- 60 people
- Sponsor
- LI FENG
Breast Ductal Carcinoma In Situ, Invasive Breast Carcinoma
Comparing Supplemental Topical Agents for the Treatment of Acute Radiation Dermatitis in Patients With Breast Cancer
This clinical trial compares two supplemental topical agents (Aquaphor and Miaderm) for the treatment of acute radiation dermatitis in patients with breast cancer undergoing radiation therapy.
- Trial name
- NCT05340673
- Testing
- Agent Affecting Integumentary System, Petrolatum-Mineral Oil-Lanolin-Ceresin Ointment, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- City of Hope Medical Center
Radiodermatitis; Acute, Radiotherapy Side Effect
The Use of Photobiomodulation in the Management of Radiodermatitis in Patients in Palliative Care. A Prospective Study.
It is estimated that there will be 670,000 new cases of cancer worldwide in 2020-2022 and it is known that the most commonly instituted treatments in cancer are chemotherapy, radiotherapy and surgery.
- Conditions
- Radiodermatitis; Acute, Radiotherapy Side Effect, Cancer Patients, Palliative Care
- Trial name
- NCT05561803
- Testing
- Photobiomodulation Therapy
- Where
- Brazil
- Sponsor
- University of Nove de Julho
Radiation Dermatitis Acute, Radiation Dermatitis
Oral or Topical Catechins for Radiation Dermatitis
Introduction Radiation-induced dermatitis (RID), which includes both acute and chronic forms, affects up to 95% of patients undergoing radiation therapy.
- Conditions
- Radiation Dermatitis Acute, Radiation Dermatitis, Fibrosis; Skin
- Trial name
- OCTOPUS-RD (NCT07149506)
- Testing
- Epicatechin, Epigallocatechin Gallate (EGCG), Saline (0.9% NaCl)
- Where
- Mexico
- Volunteers
- 162 people
- Sponsor
- CARLOS FRANCISCO SAAVEDRA GARCIA
Rectal Cancer, Radiotherapy, Anal Pain
Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin
Background: According to GLOBOCAN 2022 statistics, colorectal cancer has become the third most common cancer disease worldwide, and also the second leading cause of death.
- Conditions
- Rectal Cancer, Radiotherapy, Anal Pain, Acute Radiation Dermatitis, Anal Canal
- Trial name
- NCT06837831
- Testing
- Control group, Experimental group
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Qianfoshan Hospital
Radiodermatitis; Acute
A Study of GR1014 Cutaneous Gel for the Prevention of Skin Reactions Caused by Radiation Therapy for Breast Cancer
This clinical trial is testing a new skin gel called GR1014-CG to evaluate its safety and see if it can help prevent or reduce skin irritation (such as redness, soreness, etc.) caused by radiation therapy (RT) after…
- Trial name
- GuARD (NCT07192588)
- Testing
- GR1014-CG 2.4%, Vehicle Gel, Radiation Therapy
- Where
- 4 sites in France, United Kingdom
- Volunteers
- 273 people
- Sponsor
- Graegis Pharmaceuticals Ltd
Radiation-Induced Skin Injury
Akkermansia Muciniphila (AKK) for Radiation-Induced Skin Injury
This study is a multicenter, open-label, Phase I single-arm clinical trial evaluating the safety and tolerability of a topical AKK probiotic preparation (Akkermansia muciniphila) for the prevention and treatment of…
- Trial name
- AKK-RIS (NCT07635277)
- Testing
- AKK Topical Preparation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- West China Hospital
Radiodermatitis; Acute, Radiation Dermatitis
Novel Skin Care Product for the Management of Acute Radiodermatitis
Notwithstanding the continuous progress in cancer treatment, patients with cancer still have to cope with quality of life (QoL) - impairing complications.
- Trial name
- RTSkin (NCT04929808)
- Testing
- Hydrating emollient for acute radiodermatitis, Standard institutional skin care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Radiodermatitis
Orally Administrated JBM-TC4 Prevents Acute Radiodermatitis in Breast Cancer Patients
This trial is designed as a multicenter, double-blinded, randomized, placebo controlled study to assess the safety and efficacy of JBM-TC4 for the prevention and treatment of acute radiation-induced dermatitis in breast cancer…
- Trial name
- NCT02289365
- Testing
- 2000 mg of JBM-TC4 per day, 3000 mg of JBM-TC4 per day, 3000 mg of PEG-400 per day
- Where
- 3 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Joben Bio-Medical Co., Ltd.
Radiation-induced Dermatitis
Superoxide Dismutase Skin Spray for the Prevention of Acute Radiation Dermatitis in Head and Neck Cancer
To evaluate the efficacy and safety of superoxide dismutase skin spray for the reducing the acute radiation dermatitis in patients with head and neck malignancies undergoing radiotherapy.
- Trial name
- NCT07704372
- Testing
- A topical superoxide dismutase skin spray
- Where
- China
- Volunteers
- 140 people
- Sponsor
- West China Hospital