Clinical trials: Radiation Dosage
Radiation Dose Reduction
Tin Filter Calcium Scoring
The aim of this study is to prospectively investigate the diagnostic performance and potential radiation dose reduction in coronary artery calcium scoring using the new tin filter system of the 3rd generation DSCT scanner.
- Trial name
- NCT02855528
- Testing
- Tin Filter
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Uterine Cervical Neoplasms
The Long-term Benefit of Hydrogel Spacer in Reducing Rectal Radiation Dose in Cervical Cancer Radiation Therapy.
This study is an exploratory study based on the previous study " A prospective, multicenter, randomized, parallel arm-controlled, superiority clinical study to evaluate the role of hydrogel spacer in reducing rectal radiation…
- Trial name
- NCT05902390
- Testing
- hydrogel spacer
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cardiac Toxicity
Race Difference Moxifloxacin-induced QT Prolongation Between Healthy Chinese and Caucasian Volunteers
A double-center, randomized, double-blinded, 2-way crossover, placebo-controlled Study: Comparison of single oral dose 400mg Moxifloxacin-induced QT prolongation between healthy Chinese volunteers and Caucasian Volunteers Study…
- Trial name
- NCT02119091
- Testing
- Moxifloxacin
- Where
- 2 sites in United States, China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Haiyan Li
Obesity, Morbid
Utilization of Simulated Grid (SimGrid™) Technology for the Reduction of Ionizing Radiation Dose on X-ray Examination in Obese Patients
The purpose of this research study is to learn if a new imaging processing technique called Simulated grid (SimGrid™) will help in getting better quality X-ray images in obese subjects.
- Trial name
- NCT04161924
- Testing
- X-ray imaging with physical grid using conventional processing, X-ray imaging without physical grid using conventional processing, X-ray imaging without physical grid using experimental SimGrid offline processing
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Radiation Exposure, Urolithiasis
Study of the Patient Radiation Dose During Five Endourological Procedures
In the medical world more and more procedures are performed with the use of ionizing radiation (x-ray), both diagnostic and therapeutic.
- Trial name
- PRDE (NCT06384105)
- Testing
- frames per second
- Where
- 2 sites in Belgium
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Lumbar Disc Herniation, Radiculopathy Lumbar
The Effect of Ultrasound Guidance on Radiation Dose and Procedure Time in Lumbar Transforaminal Epidural Injection
Low back pain is one of the leading causes of disability, and its social burden and economic cost are quite high. Although there are many causes that can lead to low back pain, radicular pain, which develops mostly secondary to…
- Trial name
- NCT05793528
- Testing
- Fluoroscopy Guided Transforaminal Epidural Steroid Injection, Ultrasound Guided Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy
PET Whole Body Imaging Using a Peripheral Benzodiazepine Receptor Ligand [C-11]PBR28
In this study we will examine where the radioactive tracer [11C]PBR28 is distributed in the body of healthy volunteers to calculate the radiation exposure to organs of the body.
- Trial name
- NCT00407693
- Testing
- [C-11]PRB28
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Glioblastoma Multiforme
Safety Study of the Combination of Tandutinib With Temozolomide and Bevacizumab After Radiation and Temozolomide in Patients With Newly Diagnosed With Glioblastoma Multiforme
This is a safety study of tandutinib in combination with temozolomide and bevacizumab after people have received radiation therapy and temozolomide treatment.
- Trial name
- NCT00904852
- Testing
- Tandutinib, bevacizumab, and temozolomide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Millennium Pharmaceuticals, Inc.
Patients Treated by Radiotherapy With < One Gy to the Brain
Long Term Neurocognitive Effects of Low-dose Radiation in the Brain: Study of 150 Patients in the French Hemangioma Cohort
Context: Studies that address specifically the neurocognitive consequences that can be caused by low-dose radiation receiving during the childhood have still to be performed.
- Trial name
- CogRad (NCT01960751)
- Testing
- neurocognitive tests battery
- Where
- France
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome
This phase I trial tests the side effects and best dose of total marrow lymphoid irradiation along with chemotherapy, with fludarabine and melphalan, with or without thiotepa, in combination with Orca-T cells for patients with…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome
- Trial name
- NCT06195891
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Radiation
Intensity-modulated Radiotherapy Protocol in Cervix Cancer
Definitive treatment protocol for high-dose intensity-modulated radiotherapy (IMRT) with intracavitary radiotherapy in locally advanced cervical cancer: A phase II trial
- Trial name
- NCT02993653
- Testing
- High-dose Intensity-modulated radiotherapy
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul St. Mary's Hospital
Enteritis Caused by Radiation
Multiple Ascending Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered SYN 020
This is a Phase 1, randomized, double-blind, placebo-controlled, multiple-ascending-dose study to assess the PK, safety, and tolerability of SYN-020 oral delayed release capsules (SYN 020) in healthy adults.
- Trial name
- NCT05045833
- Testing
- SYN-020 Delayed Release Capsule
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Theriva Biologics, Inc.
Diagnostic Imaging
Evaluation of the Diagnostic Potential of BAY1006578 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of BAY1006578 in Healthy Volunteers
PET (positron emission tomography) imaging with BAY1006578 for investigation of diagnostic potential in probable Alzheimer Disease patients versus healthy volunteers and radiation dosimetry in healthy volunteers.
- Trial name
- NCT01153607
- Testing
- BAY1006578
- Where
- 2 sites in Finland, Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lantheus Biosciences Ltd.
Breast Cancer Female
Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer
Breast cancer (BC) radiotherapy leads to coincidental radiation of the heart, resulting in increased risk of a variety of heart diseases.
- Trial name
- EARLY-HEART (NCT03297346)
- Testing
- Cardiac imaging and circulating biomarkers
- Where
- 5 sites in France, Germany and 3 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- French Nuclear Safety and Radiation Protection Authority (ASNR)
Exposure to Medical Diagnostic Radiation
Low Tube Voltage Computed Tomographic (CT) Urography Using Low Concentration Iodine Contrast Agent
Computed Tomographic (CT) urography is the best imaging modality to evaluate obstructing lesions of urinary tract such as urinary stone, tumor and inflammatory lesion.
- Trial name
- NCT01855204
- Testing
- Computed tomographic urography
- Where
- South Korea
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital