Clinical trials: Radiation Effects
Cancer, Hepatocellular, Radiotherapy Side Effect
A Pilot Study For Patients Receiving Radiation Therapy for Liver Cancer
The purpose of this study is to evaluate the role of quantitative MR imaging and blood-based biomarkers to measure liver function in patients receiving radiation therapy for liver cancer or cancer that has spread to the liver.
- Trial name
- HepQuant (NCT06144827)
- Testing
- Multiparametric MRI scans, Multiparametric MRI scans + HepQuantShunt Test
- Sponsor
- Montefiore Medical Center
Breast Cancer, Neoplasm Metastasis
Liposomal Doxorubicin and Docetaxel in HER2 Negative Metastatic Breast Cancer
This is an open phase II multicentre study evaluating the efficacy and safety of the non pegylated liposomal doxorubicin (Myocet®) and docetaxel (Taxotere®) combination as first-line treatment of patients with metastatic HER2/neu…
- Trial name
- MYOTAX (NCT00377559)
- Testing
- Non pegylated liposomal doxorubicin and docetaxel
- Where
- 10 sites in Netherlands
- Volunteers
- 70 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Radiotherapy Side Effect, Nutrition Related Cancer
Nutrition Education Program for Cancer Patients Receiving Radiotherapy
Using randomized control study, explore the effect of novel nutrition education program on the nutrition status and life quality of cancer patients receiving radiotherapy
- Trial name
- NCT05329688
- Testing
- novel nutrition program
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Medical University WanFang Hospital
Cervical Cancer, Radiotherapy Side Effect
An Analysis of the Quality of Life and Sexual Quality of Life of Cervical Cancer Radiotherapy Patients
Cervical cancer radiotherapy patients have a decline in quality of life and sexual quality of life
- Conditions
- Cervical Cancer, Radiotherapy Side Effect, Quality of Life
- Trial name
- NCT03885505
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Acute Exercise Cardioprotection From Doxorubicin
In rodents, a single bout of exercise prior to injection of a chemotherapy agent used to treat breast cancer prevents or attenuates a number of markers of cardiac injury.
- Trial name
- NCT02006979
- Testing
- exercise
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of British Columbia
Breast Cancer
Effect of Concomitant Radiotherapy and Trastuzumab on Cardiotoxicity of Patients Treated for Early Breast Cancer
The purpose of this study is to determine whether concomitant radiotherapy and trastuzumab (patients treated for early breast cancer) is really safe for the heart even years after treatment and if the investigators should use…
- Trial name
- NCT01572883
- Where
- Slovenia
- Volunteers
- 175 people
- Sponsor
- Institute of Oncology Ljubljana
Breast Cancer
Evaluating 6-months of HER2-targeted Therapy in Patients With HER2 Positive Early-stage Breast Cancer That Achieve a Pathological Complete Response to Neoadjuvant Systemic Therapy
The activity of trastuzumab in early-stage, HER2-positive breast cancer, has been demonstrated in many studies, with meta-analyses showing that in combination with a variety of chemotherapy backbones, trastuzumab reduces the risk…
- Trial name
- NCT04928261
- Testing
- Trastuzumab
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Ottawa Hospital Research Institute
Breast Cancer, Cognitive/Functional Effects
Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
RATIONALE: Stereotactic radiation therapy can send x-rays directly to the tumor and cause less damage to normal tissue. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Lung Cancer, Metastatic Cancer
- Trial name
- NCT00377156
- Testing
- radiation therapy, stereotactic radiosurgery
- Where
- 64 sites in United States, Canada
- Volunteers
- 213 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Prostate Cancer, Radiotherapy Side Effect
Prostate Reirradiation Toxicity Outcomes Feasibility Study
The RO-PIP trial aims to determine the feasibility of recruitment to a trial randomising patients to salvage ultra-hypofractionated external beam radiotherapy or high dose rate brachytherapy and provide prospective data on…
- Trial name
- RO-PIP (NCT05614700)
- Testing
- Brachytherapy, Sterotactic Body Radiotherapy
- Volunteers
- 60 people
- Sponsor
- University of Leeds
Urinary Incontinence, Quality of Life
Effect of HIFEM® Treatment of Urinary Incontinence in Women in Primary Care. A Randomized Controlled Trial
Urinary incontinence (UI) is a condition with involuntary leakage of urine. UI has a significant impact on health related quality of life, poorer sleep quality and sexual function, reduced participation in social and physical…
- Conditions
- Urinary Incontinence, Quality of Life, Menopause, Mental Health Issue
- Trial name
- NCT06485167
- Testing
- HIFEM- chair
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Bone Metastases, Radiotherapy Side Effect
A Prospective Randomized Trial of High Dose Versus Standard Dose Stereotactic Radiotherapy for Pain Control in Patients With Bone Metastases
In the present study, we will prospectively evaluate the pain response and treatment failure rate to determine the most favorable radiation dose in single fraction stereotactic radiotherapy using the modern highly conformal…
- Trial name
- NCT04063254
- Testing
- Stereotactic Radiotherapy
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stage IIIA Hepatocellular Carcinoma
Radiotherapy Combined With TKI and Anti-PD-1 Antibody for Stage IIIA Hepatocellular Carcinoma
The purpose of this clinical research study is to investigate the efficacy and safety of Radiotherapy Combined with TKI and Anti-PD-1 Antibody for Stage IIIA Hepatocellular Carcinoma with Portal Vein Tumor Thrombus(PVTT).
- Trial name
- NCT06061445
- Testing
- Radiotherapy combined with TKI and Anti-PD-1 Antibody
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Fujian Cancer Hospital
Hodgkin's Disease, Lymphoma
Evaluation of Late Treatment Effects in Long-Term Survivors of Hodgkin's Disease Previously Treated at NIH: A Multi-Institutional Trial
Background: Researchers are greatly interested in knowing more about the long-term effects of various treatments for cancers such as Hodgkin's disease, particularly from those who have lived 20 to 30 years after treatment.
- Trial name
- NCT00924131
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
MIBG Scintigraphy and Strain Echocardiography in the Detection of Subclinical Cardiovascular Effects One Year After (Neo)Adjuvant Breast Cancer Treatment With Docetaxel, Doxorubicin and Cyclophosphamide (TAC): a Pilot Study
Many patients with breastcancer in the past, were treated with TAC. These last years, there is more and more focus on the effects of chemotherapy, particularly in children treated with this.
- Trial name
- TOXTAC (NCT01246856)
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Radboud University Medical Center
Head and Neck Neoplasms
Effects of Nutritional Counseling on Nutritional Status and Quality of Life of Head and Neck Cancer Patients
This study investigates the effects of nutritional counseling versus standard nutritional care on nutritional status and quality of life in patients with head and neck cancer submitted to radiotherapy.Half participants will…
- Trial name
- NCT03114202
- Testing
- intensive nutritional counseling, Standard care
- Where
- 2 sites in Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Brain Injuries
Effect of Bevacizumab on Asymptomatic Radiotherapy-induced Brain Injury
To investigate the effect of Bevacizumab on asymptomatic radiotherapy-induced brain injury patients with head and neck cancer.
- Trial name
- BRAIN (NCT05303259)
- Testing
- Bevacizumab
- Where
- China
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cervical Cancer, Radiotherapy Side Effect
Study on Adaptive Radiotherapy and Multimodal Information of Cervical Cancer Assisted by Artificial Intelligence
The standard treatment for non-operative cervical cancer is concurrent external radiation therapy and chemotherapy followed by brachytherapy.
- Conditions
- Cervical Cancer, Radiotherapy Side Effect, Biomarker, Artificial Intelligence
- Trial name
- SOARAMIOCC (NCT04022018)
- Testing
- Adaptive radiotherapy, no adaptive radiotherapy
- Where
- China
- Volunteers
- 122 people
- Sponsor
- The University of Hong Kong-Shenzhen Hospital
Breast Cancer, Cardiotoxicity
Cardiotoxicity Prevention in Breast Cancer Patients Treated With Anthracyclines and/or Trastuzumab
The aim of the study is to analyze the protective impact on the cardiac damage of beta blockers and ACE inhibitors for breast cancer patients treated with anthracyclines-based chemotherapy with or without trastuzumab.
- Trial name
- SAFE (NCT02236806)
- Testing
- Bisoprolol, Ramipril
- Where
- Italy
- Volunteers
- 262 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Radiation-Induced Oral Mucositis, Head &Amp; Neck Cancer
Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer
This study aims to find out if taking rice bran supplements can help reduce the painful mouth sores (oral mucositis) that often occur in patients with head and neck cancer who receive radiation therapy.
- Conditions
- Radiation-Induced Oral Mucositis, Head &Amp; Neck Cancer, Head &Amp; Neck Squamous Cell Carcinoma
- Trial name
- RICE-MUC (NCT07242859)
- Testing
- rice bran
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Christina Milad Lobos
To Study Immunostatus of HIV-cancer Patients Who Recived RT Befor RT and Last Week of RT, To Study HIV Viral Load of HIV-cancer Patients Who Recived RT Befor RT and Last Week of RT
Observational Study of Effect of Radiation Therapy to Immuno Status in HIV-cancer Patients
Objectives: To study immunostatus (CD4) and HIV viral load in HIV-cancer patients before RT and last weeks of RT .
- Trial name
- NCT01546376
- Testing
- Radiation therapy, Venepuncture
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
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