Clinical trials: Radiation Effects
Breast Cancer
The Effect of Myofascial Release Exercises on Viscoelastic Changes of the Pectoralis Major Muscle, Pain, Range of Motion and Shoulder Functionality in Individuals Receiving Adjuvant Radiotherapy After Breast Cancer Surgery
Chemotherapy, hormone therapy and radiotherapy used in the treatment of breast cancer try to prevent the recurrence of cancer. In addition to the benefits of radiotherapy, such as a decrease in recurrence and an increase in…
- Trial name
- NCT06764394
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Acibadem University
Upper Abdominal Malignancies
Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies
Standard planning constraints for liver SBRT incorporate strict dose-volume limits for normal liver parenchyma to minimize the risk of radiation-induced liver disease.
- Trial name
- NCT06355895
- Testing
- Standardized high-carbohydrate meal
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Pittsburgh
Breast Cancer, Radiodermatitis
Artificial Intelligence Powered Digital Education Based on the Neuman Systems Model for Breast Cancer Patients Receiving Radiotherap
The purpose of this clinical trial is to evaluate the effect of an artificial intelligence-supported digital education program developed based on the Neuman Systems Model on radiodermatitis severity and quality of life in women…
- Trial name
- NCT07649902
- Testing
- Neuman-Based AI-Supported Digital Education Program, Standard Care (in control arm)
- Volunteers
- 38 people
- Sponsor
- Ataturk University
Back Pain Without Radiation
Different Learning Methods of Motor Control Exercises
This study evaluates the effects of self-learning exercise from multimedia content on pain and disability in patients with low back pain.
- Trial name
- NCT03984903
- Testing
- Multimedia Learning of Exercises, Face-to-face Learning of Exercises, Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Anemia, Cervical Cancer
Epoetin Beta in Treating Anemia in Patients With Cervical Cancer
RATIONALE: Epoetin beta may stimulate red blood cell production to prevent or control anemia in patients treated with chemotherapy and radiation therapy.
- Trial name
- NCT00046969
- Testing
- epoetin beta, cisplatin, brachytherapy
- Where
- Germany
- Volunteers
- 450 people
- Sponsor
- AGO Study Group
Cancer, Lung Cancer
Methionine-Restricted Diet to Potentiate The Effects of Radiation Therapy
A diet consisting of a reduced quantity of the essential amino acid methionine sensitizes cancer cells to radiation therapy and reduces metastasis formation and disease progression in mice.
- Conditions
- Cancer, Lung Cancer, Prostate Cancer, Breast Cancer
- Trial name
- NCT03574194
- Testing
- Methionine-restricted diet
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- West Virginia University
Breast Cancer
Generation of Heart Muscle Cells From Blood or Skin Cells of Breast Cancer Patients
The purpose of this study is to investigate whether cells from a biopsy taken from the patient skin can be transformed into cardiomyocytes the changes in cardiomyocyte (heart muscle cells) when grown in a special culture medium…
- Trial name
- NCT02772367
- Testing
- skin punch biopsy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Radiodermatitis, Radiation Toxicity
Efficacy of the Mepitel® Film on the Prevention of Radiodermatitis in the Inguinal Fold.
The aim is to quantify the efficiency of the Safetac product Mepitel® Film on the prevention of radiodermatitis for cancer patients treated with external beam radiation therapy near the inguinal fold(s).
- Conditions
- Radiodermatitis, Radiation Toxicity, Radiotherapy Side Effect
- Trial name
- NCT04617730
- Testing
- Mepitel® film, Flamigel®
- Volunteers
- 35 people
- Sponsor
- Jules Bordet Institute
Unspecified Adult Solid Tumor, Protocol Specific
Measuring Biomarker Response to AMP-514 in Blood Samples From Patients With Solid Tumors Undergoing Radiotherapy
This pilot research trial studies the response in blood cells to AMP-514, a drug shown to increase immune response (capacity to fight against infections and cancer) against cancer in patients with solid tumors undergoing…
- Trial name
- NCT02153151
- Testing
- Cytology specimen, Laboratory biomarker analysis
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Follow-up Time, Postoperative Knee Joint Score, Postoperative X-ray, Follow-up Postural Image Data
Comparison of Curative Effect Between New Tension Band and Patellar Tension Reduction Band in the Treatment of Lower Pole Fractures of Patella
Research purposes: Analyze the curative effect of the new tension band system composed of φ3.0mm hollow nails, titanium cables and new gaskets and the patellar tension reduction band in the treatment of lower pole fractures of…
- Trial name
- NCT04960501
- Testing
- New type of tension band or patellar tension reduction band for treatment of lower pole fracture of patella
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Peking University Third Hospital
Cardiotoxicity Induced by Drug Therapy for Breast Cancer
The Use of Shengmai San to Prevent Anthracycline Sequential Trastuzumab Therapy Related Cardiac Toxicity
To evaluate the effectiveness and safety of Shengmai San in preventing anthracycline sequential trastuzumab therapy related cardiac toxicity through a prospective randomized controlled study.
- Trial name
- START (NCT06214195)
- Testing
- Shengmai San (ingredients include ginseng, Ophiopogon japonicus, and Schisandra chinensis)
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Zhejiang Cancer Hospital
Anorexia, Cachexia
Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer
RATIONALE: Megestrol helps improve appetite. It is not yet known if megestrol is effective in limiting weight loss in patients who are undergoing radiation therapy.
- Conditions
- Anorexia, Cachexia, Lung Cancer
- Trial name
- NCT00031785
- Testing
- megestrol acetate, radiation therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Radiation-Induced Mucositis
The Effect of Alpha Lipoic Acid on the Incidence and Severity of Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients
A prospective, randomized, controlled, single-blinded study will be conducted at Clinical Oncology department, Ain Shams University Hospitals, assessing the effect of Alpha Lipoic Acid on the incidence and severity of…
- Trial name
- NCT05023863
- Testing
- Alpha Lipoic Acid 600 MG Oral Tablets, radiation or concurrent chemoradiation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Multiple Myeloma, Shortness of Breath
Dyspnea and Cardiotoxicity in Multiple Myeloma Patients Who Receive Carfilzomib
This study will explore why some multiple myeloma patients who receive carfilzomib (an anti-cancer medication) experience shortness of breath while others do not.
- Conditions
- Multiple Myeloma, Shortness of Breath, Dyspnea, Cardiotoxicity
- Trial name
- NCT04827563
- Testing
- EndoPAT, Blood Pressure Cuff, Echocardiogram
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Malignant Glioma
FMISO-PET in Brain Tumors and SCS Effect
The aim of this study is to assess, with 18F-FMISO PET, hypoxia in high grade gliomas and changes by spinal cord stimulation in a subset of patients.
- Trial name
- FMISOPETSCS (NCT01868906)
- Testing
- 18F-FMISO, PET without SCS, SCS
- Where
- 2 sites in Spain
- Volunteers
- 6 people
- Sponsor
- Bernardino Clavo, MD, PhD
Cardiac Disease, Cancer
Evaluation of Reporting of Cardio-vascular Adverse Events With Antineoplastic and Immunomodulating Agents (EROCA)
Antineoplastic and immunomodulating agents may lead to various cardio-vascular adverse reactions. This study investigates reports of cardio-vascular toxicities for treatment including Anatomical Therapeutic Chemical (ATC)…
- Trial name
- EROCA (NCT03530215)
- Testing
- Antineoplastic and Immunomodulating Agents
- Where
- France
- Volunteers
- 500,000 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
SCC - Squamous Cell Carcinoma, SCC - Squamous Cell Carcinoma of Skin
Investigation of Effect of Formulated Methylene Blue on Treatment of Squamous Cell Carcinoma Skin Cancer in Inoperable Patients and Not Suitable for Radiotherapy
The goal of this clinical trial is to evaluate whether formulated methylene blue can safely and effectively treat advanced or inoperable Squamous Cell Carcinoma (SCC), a common type of skin cancer.
- Conditions
- SCC - Squamous Cell Carcinoma, SCC - Squamous Cell Carcinoma of Skin, Inoperable Disease
- Trial name
- NCT07311057
- Testing
- Formulated Topical Methylene Blue (0.5 mg/mL), Wound Healing Gel
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Daryoush Hamidi Alamdari, PhD
Cancer, Radiotherapy
Music Therapy's Effect on Cancer Patients Undergoing Radiotherapy
The goal of this randomized controlled clinical study is to learn about the effects of music therapy on anxiety, stress, pain, and patient satisfaction in cancer patients who are newly starting radiotherapy (radiation treatment).
- Trial name
- NCT07261267
- Testing
- Music Therapy, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Kocaeli University
Cancer
Effects of Probiotics Supplementation on Intestinal Microbiome in Malignancy Pts(Get Pelvic/Abdominal Rtx)
The purpose of this study is to evaluate the effect of probiotics to improve the intestinal microbiome in malignancy patients who get pelvic/abdominal radiotherapy.
- Trial name
- RTxIMprobio (NCT01706393)
- Testing
- probiotics (six probiotic cultures)
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Seoul National University Hospital
Breast Cancer
Investigating the Therapeutic Effectiveness of Aloe Barbadensis in Reducing Cutaneous Side-Effects of Radiation Treatment for Breast Cancer.
Breast cancer treatment often involved radiation to the breast. A side-effect of this treatment is skin redness, itching and burning. Some patients have quite severe reactions.
- Trial name
- NCT00156806
- Testing
- Aloe barbadensis topical application in a moisturizing cream vehicle.
- Where
- Canada
- Volunteers
- 231 people
- Sponsor
- AHS Cancer Control Alberta
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