Clinical trials: Radiation Pneumonia
Radiation Pneumonitis
Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients
This randomized clinical study aims to assess whether prophylactic treatment with inhaled steroids in patients with locally advanced or concomitantly treated non-small cell lung carcinoma who are candidates for combination…
- Trial name
- NCT03803787
- Testing
- Inhaled budesonide
- Where
- 2 sites in Mexico
- Volunteers
- 72 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Lung Cancer, Lung Metastases
Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis
The purpose of this study is to find out what effects, good and/or bad, the drug nintedanib in combination with steroids, has on the lungs. Furthermore, such treatments' side effects will be studied together with quality of life.
- Trial name
- NCT02496585
- Testing
- Nintedanib, Prednisone
- Where
- 12 sites in United States
- Volunteers
- 34 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pneumonia, Severe Acute Respiratory Syndrome
Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19
This phase III trial compares low dose whole lung radiation therapy to best supportive care plus physicians choice in treating patients with COVID-19 infection.
- Conditions
- Pneumonia, Severe Acute Respiratory Syndrome, Symptomatic COVID-19 Infection Laboratory-Confirmed
- Trial name
- RESCUE1-19 (NCT04433949)
- Testing
- Best Practice, Low Dose Radiation Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Covid19
Evaluation of a COVID-19 Pneumonia CXR AI Detection Algorithm
This study investigates the diagnostic performance of an AI algorithm in the detection of COVID-19 pneumonia on chest radiographs.
- Trial name
- NCT04561024
- Testing
- AI model
- Where
- Hong Kong
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ensemble Group Holdings, LLC
Lung Cancer
Ventilation Imaging to Improve the Quality of Life for Patients With Lung Cancer Treated With Radiation Therapy
This research project is testing a new treatment planning method for patients with lung cancer who will be treated with radiation therapy. This new method is called Computed Tomography (CT) ventilation imaging.
- Trial name
- VITaL (NCT06127654)
- Testing
- Healthy lung sparing treatment plan
- Where
- Australia
- Volunteers
- 165 people
- Sponsor
- University of Sydney
Pneumonia
Value of Radiological Follow up in Children Hospitalized With Lobar Pneumonia
The study intends to assess the utility of performing a follow up X rays in children admitted to pediatric wards with lobar pneumonia.
- Trial name
- NCT00735592
- Testing
- Observational
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- HaEmek Medical Center, Israel
Lung Cancer
Phase II Evaluation of Exhaled Nitric Oxide (NO)
The goal of this clinical research study is to learn if the level of nitric oxide you breathe out may relate to the amount of breathing complications that you may experience due to radiation treatment.
- Trial name
- NCT01392144
- Testing
- Nitric oxide breath test, Questionnaires
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- M.D. Anderson Cancer Center
Locally Advanced Non Small Cell Lung Cancer
Prevention of Locally Advanced NSCLC Radiotherapy Pneumonia by Inhaling Beclomethasone Propionate
Radical radiotherapy is the main treatment of locally advanced lung cancer, and radiation pneumonia is the main toxic effects of radiotherapy.
- Trial name
- NCT03886441
- Testing
- Beclomethasone propionate
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Tongji University
Lower Respiratory Infection, LRTI
Effectiveness of Point-of-care Lung Ultrasound for the Management of Childhood Lower Respiratory Infections
The goal of this clinical trial is to evaluate the effectiveness of point-of-care lung ultrasound versus chest X-ray for the management of childhood lower respiratory infections in a low-resource setting.
- Conditions
- Lower Respiratory Infection, LRTI, Pneumonia, Bronchiolitis
- Trial name
- ELUS (NCT05921526)
- Testing
- Point-of-care lung ultrasound, Chest X-ray (digital images)
- Where
- Nepal
- Volunteers
- 616 people
- Sponsor
- Nagasaki University
COVID-19, Pneumonia
Low Dose Radiation Therapy for Covid-19 Pneumonia
Radiotherapy in low doses (30 to 100 cGy) was a popular treatment of viral pneumonias until 1940s. Low dose radiation therapy (LDRT) could possibly reduce the inflammation and prevent the cytokine storm thus mitigating the…
- Trial name
- NCT04394793
- Testing
- Low dose radiation therapy
- Where
- India
- Volunteers
- 10 people
- Sponsor
- All India Institute of Medical Sciences
Lung Cancer, Interstitial Lung Disease
Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease
In this double-blind phase II randomized controlled trial, patients with lung cancer or ≤2 oligometastatic pulmonary lesions and a concomitant diagnosis of ILD who are planned for radical Radiation Therapy (RT) will be randomized…
- Trial name
- RESPIRE-ILD (NCT05986318)
- Testing
- N-Acetyl cysteine, Dexamethasone Oral, Radiation Therapy
- Where
- 4 sites in Canada
- Volunteers
- 98 people
- Sponsor
- David Palma
Pneumonia
Validation of Thermal Imaging to Detect Pneumonia
The investigators are proposing a two-stage, prospective, cohort study of 138 subjects > 28 days old and < 18 years old with respiratory distress, already getting a chest x-ray as part of their routine clinical care, who will get…
- Trial name
- NCT03261479
- Testing
- Thermal image
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Massachusetts General Hospital
Radiation Pneumonitis
Risk Factors of Radiation Pneumonitis
A prospective observational study to evaluate clinical, dosimetrical, functional, and biological factors in predicting radiation pneumonitis.
- Trial name
- NCT00155909
- Where
- Taiwan
- Volunteers
- 53 people
- Sponsor
- National Taiwan University Hospital
Covid19
Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia
The purpose of this study is to document the feasibility and tolerability of low dose thoracic radiotherapy in patients with WHO level 5 COVID 19 infections.
- Trial name
- NCT04572412
- Testing
- Low dose Radiotherapy
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Lung Cancer, Radiation Therapy Complication
Xenon-enhanced Ventilation CT-guided Radiotherapy for Lung Cancer Treatment
The investigators aim to use xenon-enhanced ventilation computed tomography (CT) to design personalized functional lung avoidance radiotherapy for lung cancer patients who are scheduled to receive lung radiation therapy.
- Trial name
- NCT05134558
- Testing
- Xenon-enhanced Ventilation CT-guided Radiotherapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Dyspnea
Artificial Intelligence to Improve Physicians' Interpretation of Chest X-Rays in Breathless Patients
Identifying the cause of breathlessness in acute patients in the emergency department is critical and challenging. The chest X-ray is central but challenging to read for non-radiologist physicians.
- Trial name
- XRAI (NCT05117320)
- Testing
- AI support
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Carcinoma, Non-small-cell Lung
Prevention of Radiation Pneumonitis After Three-dimensional Conformal Radiation Therapy (3D-CRT) in Patients With Non-small-cell Lung Cancer
The purpose of this study is to evaluate the interest of breath holding for the prevention of radiation pneumonitis following conformal radiation therapy.
- Trial name
- NCT00349102
- Testing
- Free breathing, Breath holding
- Where
- 7 sites in France
- Volunteers
- 242 people
- Sponsor
- Centre Leon Berard
COVID-19, H1N1 Influenza
Comparison of COVID-19 and H1N1 Influenza Pneumonia
To explore the different clinical and CT features distinguishing COVID-19 from H1N1 influenza pneumonia.
- Trial name
- NCT04933994
- Testing
- computed Tomography
- Volunteers
- 483 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronavirus Disease 2019
Identify Coronavirus Disease by Chest X-ray
to identify the diagnostic accuracy of chest X-ray in diagnosis of Coronavirus disease19 .
- Trial name
- NCT05216471
- Testing
- chest X-ray
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Radiation Pneumonitis, Endostatin
Clinical Study of Endostatin in Improving Radiation Pneumonia and Fibrosis
To verify the efficacy and safety of endostatin in the treatment of SRILI（symptomatic radiation-induced lung injury） and fibrosis.
- Trial name
- NCT03796364
- Testing
- Endostar, standard SRILI treatment
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Xinqiao Hospital of Chongqing