Clinical trials: Radiation Protection
Ototoxicity, Hearing Loss
The Protective Effect of Ginkgo Biloba Extract on Cisplatin-induced Ototoxicity in Humans
The proposal of this study was to evaluate in human beings, using distortion product otoacoustic emission (DPOAE) test, the action of ginkgo biloba extract (GBE761)as a possible ear protective against cisplatin (CDDP) induced…
- Trial name
- NCT01139281
- Testing
- Ginkgo Biloba Extract (GBE761)
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Brasilia
Radiation Protection, Image Enhancement
Next-Generation Photon-Counting CT Technology: Development and Clinical Evaluation
This project aims to develop and evaluate a next-generation photon-counting CT prototype, and assess whether next-generation photon-counting CT--which enables reduced radiation dose, high spatial resolution, and spectral…
- Trial name
- CT-DACE (NCT06691659)
- Testing
- CT-DACE
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Pennsylvania
Cholangiopancreatography, Endoscopic Retrograde, Occupational Exposure
Radiation Exposure During Endoscopic Retrograde Cholangiopancreatography
Radiation now becomes a dreadful effect as its outcomes are tremendous to be expected. As a result, anesthetists become an inevitable target to the radiation exposure since they have to monitor patients closely during the…
- Conditions
- Cholangiopancreatography, Endoscopic Retrograde, Occupational Exposure, Radiation Injuries
- Trial name
- NCT02985164
- Testing
- PDSa, PDSb
- Volunteers
- 222 people
- Sponsor
- Siriraj Hospital
Radiation Exposure, Knowledge, Attitudes, Practice
Knowledge and Attitude of the Operating Room Nurses About Radiation Exposure
This study aims to evaluate the level of knowledge and attitude of the operating room nurses about radiation exposure.This descriptive study was conducted with 100 nurses working in the operating room of two university hospitals…
- Trial name
- NCT04703933
- Testing
- EVALUATION OF THE LEVEL OF KNOWLEDGE AND ATTITUDE OF THE OPERATING ROOM NURSES
- Volunteers
- 100 people
- Sponsor
- Acelya Turkmen
Oxidative Stress, DNA Damage, Radiation Induced
Multi-Nutrient Supplement for Radio-Protection
Exposure to radiation, such as during routine CTs, bone scans, or X-rays, causes oxidative stress which can damage the DNA (your genetic material) within your white blood cells.
- Conditions
- Oxidative Stress, DNA Damage, Radiation Induced, Radiation Exposure
- Trial name
- MNSRP (NCT04781868)
- Testing
- Multi-nutrient supplement
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Any Pathology Requiring a Cranial CT Imaging
Crystalline Exposition During Pediatric Cranial CT Imaging
This study focuses on reduction of X-rays dose applied to eye's lens during cranial CT in children. Principal objective is to analyse the efficiency of ocular bismuth masks, which are associated with an eye's lens dose modulation
- Trial name
- ECTOPIC (NCT03665181)
- Testing
- use or non-use of dose modulator and bismuth mask
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Bordeaux
Radiation Exposure
Suspended Personal Protection System Versus Conventional Protection (Aka Zero-Gravity vs Shield and Apron)
This trial investigates operator radiation doses when performing standardized procedures using two different means of radiation protection, namely conventional lead shield and apron versus suspended protection system…
- Trial name
- NCT04078165
- Testing
- Zero-Gravity, Conventional radiation protection
- Where
- Finland
- Volunteers
- 72 people
- Sponsor
- Helsinki University Central Hospital
Ergonomics, Orthopedic Injury
Ergonomics in the Cardiac Catheterization Laboratory
The goal of this observational study is to quantify ergonomic risk associated with traditional protective equipment in operators working in the cardiac catheterization laboratory as compared with a mobile protection system.
- Conditions
- Ergonomics, Orthopedic Injury, Wellness
- Trial name
- ERGO-CATH (NCT06506968)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Non Small Cell Lung Carcinoma
Phase II Study of Celecoxib and Concurrent Radiotherapy in Stage II-III NSCLC
The purpose of this study is to investigate the effect of the adminstration of celecoxib, a cox2-inhibitor in patients with stage II-III non small cell lung cancer receiving radical radiotherapy.
- Trial name
- NCT00181532
- Testing
- Celecoxib
- Where
- Netherlands
- Volunteers
- 102 people
- Sponsor
- Maastricht Radiation Oncology
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture
IOPS Technology During Cannnulation of Contralateral Limb in EVAR
Short-term results are favorable for EndoVascular Aneurysm Repair (EVAR) compared to open surgery. One of the major drawbacks to this shift is the need for fluoroscopy and contrast dyes to visualise endovascular devices.
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Radiation Exposure
- Trial name
- IOPS (NCT06570785)
- Testing
- Intra-Operative Positioning System (IOPS), Conventional group
- Where
- Serbia
- Volunteers
- 80 people
- Sponsor
- Clinical Centre of Serbia
Polymorphic Light Eruption
Sunscreen and After-sun-lotion Protection in Polymorphic Light Eruption
Polymorphic light eruption (PLE) is a common photodermatosis characterized by the appearance of itching, erythema, papules or vesicles on sun-exposed skin.
- Trial name
- NCT00549588
- Testing
- After-sun-lotion with DNA repair enzymes, SPF30 sunscreen, Intervention: none (only UV)
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Graz
Toxic Nodular Goitre, Graves' Disease
Block-replacement Therapy During Radioiodine Therapy
Background: The use of radioactive iodine (131I) therapy as the definite cure of hyperthyroidism is widespread. According to a survey on the management of Graves' disease, thirty per cent of physicians prefer to render their…
- Trial name
- NCT00150124
- Testing
- MTZ+LT4, Methimazole
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Steen Bonnema
Central Nervous System Carcinoma
A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for a Brain Tumor
This phase III trial compares memantine to placebo in treating patients with primary central nervous system tumors. Memantine may block receptors (parts of nerve cells) in the brain known to contribute to a decline in cognitive…
- Trial name
- NCT04939597
- Testing
- Biospecimen Collection, Cognitive Assessment, Magnetic Resonance Imaging
- Where
- 138 sites in United States, Puerto Rico
- Volunteers
- 162 people
- Sponsor
- Children's Oncology Group
Radiation Exposure to Operator
Physician Radiation Exposure During Radial Access Cardiac Catheterization Using a RAD Board
Radiation exposure to operator is an occupational hazard of invasive cardiologists. During radial access for diagnostic catheterization, a new radio-dense arm board is advertised to reduce operator radiation exposure.
- Trial name
- NCT02088788
- Testing
- Board, No Board
- Where
- United States
- Volunteers
- 265 people
- Sponsor
- Geisinger Clinic
Coronary Artery Disease
Prospective Randomized Trial On Radiation Dose Estimates Of CT Angiography In Patients Applying Iterative Image Reconstruction Techniques - The PROTECTION V Study -
The objective of this study is to compare a standard coronary CT angiography scan protocol with conventional image reconstruction with a scan protocol using reduced tube current and a new image reconstruction algorithm.
- Trial name
- PROTECTION-V (NCT01453712)
- Testing
- Control group, Intervention group
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Study on the Use of Lateral Decubitus Position in Left Breast Cancer Patients Undergoing Adjuvant Radiotherapy
A Prospective Study on the Application of Lateral Decubitus Position in Patients with Left Breast Cancer Undergoing Adjuvant Radiotherapy
- Trial name
- LDPLBC (NCT06902051)
- Testing
- Lateral Decubitus position, Lateral Decubitus device
- Where
- 2 sites in China
- Volunteers
- 86 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Exposure
New Fabric Attenuation Device in Endovascular Interventional Radiology (PREFER)
The PREFER Trial primary objective of the trial is to show how much radiation attenuation is provided by XPF in absolute and relative terms.
- Trial name
- PREFER (NCT01450969)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baptist Health South Florida
Head and Neck Cancer, Adaptive Radiotherapy
Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors
Adaptive radiotherapy (ART) includes image-guided radiotherapy (IGRT) and also offers further possibilities for plan adaptation.
- Conditions
- Head and Neck Cancer, Adaptive Radiotherapy, Radiation, Optimized Treatment
- Trial name
- ART in HNT (NCT06214611)
- Testing
- Adaptive Radiotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen
Coronary Artery Disease, Coronary Disease
Prospective Multicenter Registry On Radiation Dose Estimates Of Cardiac CT Angiography in Daily Practice in 2017 (PROTECTION VI)
Background: CCTA is a common way to evaluate coronary artery disease. It stands for coronary computed tomography angiography. It uses scanning to look at the arteries that supply blood to the heart.
- Conditions
- Coronary Artery Disease, Coronary Disease, Myocardial Ischemia, Arterial Occlusive Diseases
- Trial name
- NCT03253692
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sunburn
Water Immersion Studies of a Long-wear Sunscreen to Improve Protection Against Ultraviolet Radiation
This study is designed to determine the Sun Protection Factor (SPF) of a test product following 80 Minute Water Immersion methodology defined in Final Monograph - Code of Federal Regulations Title 21 - "Labeling and Effectiveness…
- Trial name
- NCT05767008
- Testing
- Sunscreen -R43
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nanometics (d.b.a. PHD Biosciences)