Clinical trials: Radiation Protection, open to volunteers
Sunburn
Randomized Trial of a Sun Safety Intervention for Young Adults
The goal of this randomized controlled trial is to test the efficacy of a dissonance induction intervention compared to a control group on tanning in 278 young adult tanners. The primary outcome will be tanning at 3-months.
- Trial name
- NCT07751406
- Testing
- Healthy Skin, Healthy Lifestyle
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Melanoma (Skin Cancer)
Sun Exposure and Activities After Skin Cancer: Optimization of mHealth Interventions
The purpose of this study is to evaluate 5 different smartphone administered sun protection interventions that aim to reduce unprotected sun exposure in melanoma survivors.
- Trial name
- SESAME (NCT07556380)
- Testing
- UV Real-Time Alerts, Track Your Sun Protection, Current Conditions
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Northwestern University
Radiation Exposure, Radiation Exposure to Operator
The Radiation ProtEction for Dose RedUction in the Cardiac CathEter Lab Study: The REDUCE Trial
Doctors and nurses who perform heart procedures using X-ray guidance are exposed to radiation, which can be harmful over time. This exposure increases the risk of certain health problems, including cancers, eye damage…
- Conditions
- Radiation Exposure, Radiation Exposure to Operator, Radiation Injuries, Radiation Safety
- Trial name
- REDUCE (NCT06875583)
- Testing
- Radiation
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Knowledge
Knowledge and Attitudes About Advanced Maxillofacial Imaging in Dental Professionals
Introduction: Advanced maxillofacial imaging techniques, such as CBCT, CT, MRI, and hybrid modalities (PET/CT and SPECT/CT), have transformed diagnosis and treatment planning in dentistry.
- Trial name
- KAAMI (NCT07651969)
- Testing
- Submit a questionnaire
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Radiation Protection
Study to Evaluate the Clinical Utility of Radiation Exposure Reduction: Multi-site Rampart Guardian Peripheral Trial
Study to Evaluate the Clinical Utility of Radiation Exposure Reduction (SECURE): Multi-site Rampart Guardian Peripheral Trial
- Trial name
- SECURE (NCT07467720)
- Testing
- Rampart IC System
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Baylor Research Institute
Sunburn, Sun Damaged Skin
Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics
The purpose of this study is to assess how human skin reacts and how sunscreens and sun protection fabrics protect in natural sunlight compared to their labeled claims, indoor testing methods (existing or modified) and…
- Conditions
- Sunburn, Sun Damaged Skin, Overexposure to Sun Rays
- Trial name
- NCT03007589
- Testing
- otc sunscreens, sun protection fabrics, Optical Filters
- Where
- 5 sites in United States, Chile and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Protection Foundation
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture
IOPS Technology During Cannnulation of Contralateral Limb in EVAR
Short-term results are favorable for EndoVascular Aneurysm Repair (EVAR) compared to open surgery. One of the major drawbacks to this shift is the need for fluoroscopy and contrast dyes to visualise endovascular devices.
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Radiation Exposure
- Trial name
- IOPS (NCT06570785)
- Testing
- Intra-Operative Positioning System (IOPS), Conventional group
- Where
- Serbia
- Volunteers
- 80 people
- Sponsor
- Clinical Centre of Serbia
Kidney Failure, Acute, Myopathy; Drugs
The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)
The study aims to improve the safety of the electroporation ablation (PFA) procedure by using muscle relaxants to reduce skeletal muscle damage during the procedure.
- Conditions
- Kidney Failure, Acute, Myopathy; Drugs, Heart Arrhythmia, Succinylcholine Sensitivity
- Trial name
- NCT06707532
- Testing
- Propofol, Rocuronium
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Primary Lung Cancer, Non Small Cell Lung Cancer
Prophylactic Proton Pump Inhibition for Esophageal Protection in Lung Radiation Therapy
A randomized controlled trial to assess the impact of prophylactic proton pump inhibitor use to improve esophagitis in lung cancer patients undergoing radiation.
- Conditions
- Primary Lung Cancer, Non Small Cell Lung Cancer, Small Cell Lung Cancer
- Trial name
- PPI-PROTECT (NCT07076914)
- Testing
- Experimental (Health Canada Approved Proton Pump Inhibitors)
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypothyroidism; Irradiation
TSH Suppression During Radiotherapy on Thyroid Site to Prevent Iatrogenic Hypothyroidism in Pediatric Cancer Patients
To offer the possibility of a treatment that could achieve a meaningful reduction in the incidence of post-radiation therapy hypothyroidism.
- Trial name
- WIN-HYPO2021 (NCT05316922)
- Testing
- Levothyroxine
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Hepatocellular Carcinoma
A Pilot Study of Liver Protection Using Prednisone for Patients Receiving Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma
Patients on this study will self administer Prednisone for three days before starting Radiation Therapy (RT) and continue to take 60 mg/day during the first three fractions of RT.
- Trial name
- NCT05901519
- Testing
- Prednisone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan Rogel Cancer Center
Epidermis, Ultraviolet Exposure
A Clinical Study to Evaluate the Efficacy and SPF of Two Test Materials According to an Adaptation of the Guidelines of the FDA Sunscreen Drug Products for Over-the-Counter Human Use
Approximately 70 subjects (35 subjects per light and dark group) will be enrolled in this clinical study (to complete with a minimum of 10 subjects per skin type (I-VI) to assess the effects of known UV Radiation dosage on light…
- Trial name
- NCT07789639
- Testing
- Hybrid sunscreen, Chemical sunscreen, No sunscreen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Good Molecules, LLC
Nasopharyngeal Carcinoma, Quality of Life
Prophylactic Radiotherapy Optimization for Enhanced Thyroid Function Protection in NPC
This study is a multicenter, non-inferiority, open-label, randomized controlled Phase III clinical trial. It aims to compare the efficacy of modified delineation radiotherapy (experimental group) versus standard delineation…
- Conditions
- Nasopharyngeal Carcinoma, Quality of Life, Thyroid Diseases, Radiotherapy Side Effect
- Trial name
- PROTECT-NPC (NCT06752239)
- Testing
- Modified delineation, Standard delineation
- Where
- China
- Volunteers
- 474 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Radiation Protection, Image Enhancement
Next-Generation Photon-Counting CT Technology: Development and Clinical Evaluation
This project aims to develop and evaluate a next-generation photon-counting CT prototype, and assess whether next-generation photon-counting CT--which enables reduced radiation dose, high spatial resolution, and spectral…
- Trial name
- CT-DACE (NCT06691659)
- Testing
- CT-DACE
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Pennsylvania
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Study on the Use of Lateral Decubitus Position in Left Breast Cancer Patients Undergoing Adjuvant Radiotherapy
A Prospective Study on the Application of Lateral Decubitus Position in Patients with Left Breast Cancer Undergoing Adjuvant Radiotherapy
- Trial name
- LDPLBC (NCT06902051)
- Testing
- Lateral Decubitus position, Lateral Decubitus device
- Where
- 2 sites in China
- Volunteers
- 86 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Radiation Exposure
Clinical Evaluation of a Novel Textile Radiation Protection Device
This study will use procedure-specific dosimetry to evaluate whether Texray's novel woven radiation protection fabric (HeadPeace and MindPeace) reduces occupational radiation dose to the head and thyroid of interventional…
- Trial name
- NCT07768605
- Testing
- Standard PPE, Texray PPE
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Medulloblastoma Tumor
Evaluation of The Radioprotective Effect of 3D-Printed Intraoral Stents in Children With Brain Cancer.
Brain cancer patients undergoing radiotherapy may experience oral complications such as oral mucositis, gingival inflammation, plaque accumulation, radiation-induced caries, and reduced oral-health-related quality of life due to…
- Trial name
- NCT07715357
- Testing
- 3D printed intraoral stents.
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
DNA, Cancer
Optimization of Radiation Protection Through Genomic Analyses
The long-term goal is to define "signatures" in the form of genomic changes through sequence analyses of genomic DNA using modern Next Generation Sequencing (NGS) methods, which 1. determine the radiation exposure of humans. 2.
- Conditions
- DNA, Cancer, Radiation
- Trial name
- ORtogether (NCT06253338)
- Testing
- genomic alterations
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen