Clinical trials: Radiation Treatment
Effects of Chemotherapy
Assessing Fertility Potential in Female Cancer Survivors
Hypothesis: Girls and women exposed to chemotherapy and/or radiation therapy experience endocrine changes more similar to women in their late reproductive years than to same-age peers.
- Trial name
- NCT01143844
- Where
- 2 sites in United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pain, Inflammation
UVB Model Validation Study
Single centre, subject and observer blinded, placebo controlled, cross-over study of the effect of oral ibuprofen and topical hydrocortisone-21-acetate on ultraviolet radiation (UVR) induced pain and inflammation in healthy…
- Conditions
- Pain, Inflammation, Healthy Volunteers
- Trial name
- NCT01055249
- Testing
- Ibuprofen, Hydrocortisone, Hydrocortisone
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- X-pert Med GmbH
Healthy
A Study to Investigate the Whole Body Distribution and Radiation Dosimetry of the Positron Emission Tomography Ligand Fluoride-18 (18F)-JNJ-64326067 in Healthy Participants
The purpose of this study is to measure the whole-body distribution and radiation dosimetry of 18F-JNJ-64326067 in healthy participants.
- Trial name
- NCT03581916
- Testing
- 18F-JNJ-64326067
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Xerostomia Due to Radiotherapy (Disorder)
Screening of Biomarkers and Related Mechanisms for RIX
A large number of patients undergoing radiotherapy and chemotherapy are suffering from dry mouth. Due to reduced saliva secretion, patients may experience symptoms such as difficulty chewing and swallowing.
- Trial name
- RIX (NCT06700863)
- Testing
- Radiation Therapy
- Where
- 4 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Healthy Volunteers
Feasibility of Upskilling Non-Radiology Personnel in X-ray
The goal of this feasibility study is to learn if individuals without formal radiology training can safely acquire adequate x-ray images following a structured training and real-time remote guidance from a licensed radiologic…
- Trial name
- NCT07713563
- Testing
- X-ray Operator Training
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Over-Active Bladder
VESIcare For Improving OAB Symptoms in Patients Undergoing IGRT of the Prostate
The purpose of this study is to determine if Vesicare (Solifenacin succinate) is effective in treating over-active bladder symptoms during radiation therapy of the prostate.
- Trial name
- NCT01777217
- Testing
- Solifenacin succinate
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Advanced Research Network
Health Physics, Healthcare Professionals, Toolbox Trainings
The Effect of Toolbox Training on Radiation Protection Practices of Health Professionals in Radioactive Workplaces
This study will be conducted in a randomized controlled, pre-test, post-test and experimental group design to determine the effects of on-the-job training on radiation workers (radiation safety, protective clothing, awareness).
- Trial name
- NCT06530121
- Testing
- Toolbox trainings
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Disease
A Phase I Study in Healthy Volunteers to Evaluate the Safety of CardioPET™ in Detection of Coronary Artery Disease
Safety and dosimetry of CardioPET™ will be evaluated in normal healthy volunteers and CAD subjects both male and female between the ages of 50-85.
- Trial name
- NCT00413647
- Testing
- CardioPET
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Fluoropharma, Inc.
Head and Neck Cancer
Clinical Trial on the Efficacy and Safety of Chining Decoction in the Treatment of Radiation Stomatitis
This study evaluates the efficiency and safety of ChiNing decoction to head and neck cancer patients with radioactive stomatitis.
- Trial name
- NCT02303197
- Testing
- ChiNing decoction
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Spinal Metastases, Spinal Tumor
En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.
The purpose of this clinical trial is to explore the impact of En bloc surgery and separation surgery combined with radiation therapy on the prognosis and survival of patients with spinal oligometastatic cancer, describe the…
- Conditions
- Spinal Metastases, Spinal Tumor, Radiotherapy, Malignant Bone Tumor
- Trial name
- NCT06120426
- Testing
- total en bloc spondylectomy
- Where
- China
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Primary Brain Tumor, Radiation Toxicity
Cognitive Function After Radiation Therapy for Brain Tumours
This study will assess cognitive function in adult patients with a primary brain tumour treated with surgical resection with or without radiation therapy (RT). All types of brain tumours apart from glioblastoma will be included
- Trial name
- WP-12-pre (NCT04118426)
- Testing
- Cognitive testing
- Where
- Denmark
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Recurrent Prostate Cancer After Surgery
This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
There is significant, proven use of radiation for recurrent prostate cancer after surgical resection. This treatment typically is delivered over seven and a half weeks of daily treatments, presenting a burden to patients and the…
- Trial name
- DASBRT-RPC (NCT05946824)
- Testing
- Daily-adaptive Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Colorectal Cancer
Radiation Therapy on Pelvic Floor Disorders in Women
Investigators propose a retrospective cohort study to examine the impact of radiation therapy on the global pelvic floor function of women who have completed the immediate surveillance period for colorectal cancer
- Trial name
- RadPFD (NCT04623515)
- Testing
- REDCap Questionnaires
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Glioma, Breast Cancer
68Ga-NOTA-NFB: Radiation Dosimetry in Healthy Volunteers and Applications in Glioma Patients or Breast Cancer Patients
The purpose of this study is to assess the safety, biodistribution, dosimetric properties of the positron emission tomography (PET) radiopharmaceutical agent 68Ga-NOTA-NFB.
- Trial name
- GNNGB (NCT02327442)
- Testing
- 68Ga-NOTA-NFB
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Healthy Subjects, Rheumatoid Arthritis
Biodistribution, Dosimetry and Performance of [68Ga]Ga-DOTA-Siglec-9 in Healthy and Patients With Rheumatoid Arthritis, Vasculitis or Pulmonary Sarcoidosis
This study evaluates safety, tolerability, biodistribution and performance of the [68Ga]Ga-DOTA-Siglec-9 following a single intravenous administration in patients with active rheumatoid arthritis, vasculitis or pulmonary…
- Conditions
- Healthy Subjects, Rheumatoid Arthritis, Vasculitis, Pulmonary Sarcoidosis
- Trial name
- SIGLEC (NCT03755245)
- Testing
- [68Ga]Ga-DOTA-Siglec-9
- Where
- Finland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Neoplasm Metastasis, Carcinoma
Helical Tomotherapy as a Radiotherapy Technique for Treating Pelvic and Abdominal Metastases
Radiation treatment is often used to treat cancer that has spread to the abdomen. It can be very effective at relieving symptoms such as pain, but the radiotherapy itself can cause side-effects such as cramping and diarrhea.
- Trial name
- NCT00129051
- Testing
- Tomotherapy
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alberta Health services
Healthy Volunteers, Breast Cancer
Study to Evaluate the Safety, Biodistribution, Radiation Dosimetry and Tumor Imaging Potential of [131I]-SGMIB Anti-HER2 VHH1 in Healthy Volunteers and Breast Cancer Patients
Primary purpose of the clinical study is to evaluate the safety, biodistribution and radiation dosimetry of [131I]-SGMIB Anti-HER2 VHH1 in healthy volunteers and patients with HER2+ breast cancer.
- Trial name
- CAM-VHH1 (NCT02683083)
- Testing
- [131I]-SGMIB Anti-HER2 VHH1
- Where
- Belgium
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Precirix
Radiation Disease
Pelvic Radiation Disease in Childhood Cancer Survivors
This study aims to characterise the impact of radiotherapy on physical symptoms and quality of life in childhood and young adult cancer survivors.
- Trial name
- NCT05533541
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Head and Neck Cancer, Chronic Periodontitis
Estimation of (suPAR) in Chronic Periodontitis With Post-radiotherapy on HNCs Patients
This study aims to improve a soluble urokinase plasminogen activator receptor suPAR is a reliable biomarker of chronic periodontitis and may be replaced in patients with head and neck cancer post-radiotherapy (HNC post-RT).
- Conditions
- Head and Neck Cancer, Chronic Periodontitis, Radiotherapy Side Effect
- Trial name
- HNCs (NCT06529588)
- Testing
- Radiation
- Where
- Iraq
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Al-Maarif University College
Coronary Artery Disease
A Phase I Study to Evaluate BFPET as a Potential Myocardial Perfusion Imaging(MPI) Agent for PET
Safety and dosimetry of BFPET™ will be evaluated in healthy volunteers and Coronary Artery Disease (CAD) patients , male or female and of age ranging between 20-80 years old.
- Trial name
- NCT00733460
- Testing
- BFPET
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fluoropharma, Inc.