Clinical trials: Radiation-Induced Mucositis
Radiation-induced Oral Mucositis, Head and Neck Cancer
Citrus Sinensis Peel Gel for Radiation-Induced Oral Mucositis
This randomized controlled clinical trial aims to evaluate the efficacy of Citrus sinensis peel extract gel in the treatment of radiation-induced oral mucositis in head and neck cancer patients.
- Trial name
- NCT07813923
- Testing
- Citrus sinensis peel extract gel, Conventional supportive treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Radiation Induced Oral Mucositis
Benzydamine vs Supersaturated Calcium Phosphate Oral Rinses for Radiation Induced Oral Mucositis in Head and Neck Cancer Patients.
The goal of this clinical trial is to compare and correlate salivary macrophage migratory inhibitory factor levels with onset and severity of radiation induced mucositis in head and neck cancer patients by using super saturated…
- Trial name
- NCT07748442
- Testing
- Benzydamine hydrochloride mouthrinse, Super saturated calcium phosphate oral rinses
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Radiation Induced Oral Mucositis, Radiodermatitis
Taurine's Therapeutic Effect on Acute Radiation-induced Oral Mucositis and Dermatitis
This is a single-center, double-blind, randomized controlled study. The patients were divided into control group and experimental group, 80 cases each.
- Trial name
- NCT07029178
- Testing
- Taurine granule
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Radiation-Induced Oral Mucositis (RTOM), Head and Neck Cancer
Sancai Fengsui Decoction for RTOM: A Multicenter RCT
How to promote the prognosis and outcome of RTOM, restore oral function, and improve quality of life are key issues for improving the long-term outcomes of head and neck malignant tumor radiotherapy, and are also integral parts…
- Conditions
- Radiation-Induced Oral Mucositis (RTOM), Head and Neck Cancer, Oral Mucositis of RTOG Grade Greater Than 1
- Trial name
- NCT07692997
- Testing
- Sancai Fengsui Decoction
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Nasopharyngeal Cancinoma (NPC), Radiation-induced Oral Mucositis
Prevention and Treatment of Radiation-Induced Oral Mucositis in NPC With Houyanqing Oral Liquid
To explore the efficacy of Houyanqing Oral Liquid combined with conventional treatment in preventing and treating radiation-induced oral mucositis, so as to improve the quality of life of nasopharyngeal carcinoma patients…
- Trial name
- NCT07311772
- Testing
- Houyanqing Oral Liquid, Conventional Treatment for Radiation-Induced Oral Mucositis
- Where
- 16 sites in China
- Volunteers
- 386 people
- Sponsor
- Sun Yat-sen University
Radiotherapy-Induced Oral Mucositis, Stomatitis
Traditional Chinese Medicine for the Prevention of Radiotherapy-Induced Oral Mucositis (RTOM)
This is a multicenter, randomized, controlled, prospective clinical trial designed to observe and evaluate the safety and efficacy of Modified Dahuang Huanglian Xiexin Mouthwash for the prevention of radiotherapy-induced oral…
- Conditions
- Radiotherapy-Induced Oral Mucositis, Stomatitis, Oral Mucositis, Radiotherapy Side Effects
- Trial name
- NCT07543978
- Testing
- Modified Dahuang Huanglian Xiexin Mouthwash
- Volunteers
- 156 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Radiation-induced Oral Mucositis, Oral Malignancy
A Phase II Prospective, Open-Label, Randomized, Multicenter Study of Kangfu Spray for the Prevention of Radiation-Induced Oral Mucositis in Patients With Oral Malignancies Receiving Intensity-Modulated Radiotherapy
This is a prospective, open-label, randomized, controlled, multicenter phase II study evaluating the efficacy and safety of Kangfu Spray for the prevention of radiation-induced oral mucositis in patients with histologically…
- Trial name
- NCT07538934
- Testing
- Kangfu Spray, Standard Oral Care
- Volunteers
- 140 people
- Sponsor
- YE ZHANG
Radiation-induced Oral Mucositis
Spirulina-Derived Product Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors
To evaluate the efficacy and safety of Spirulina-Derived Product for prevention and treatment of oral mucositis in patients undergoing radiotherapy for malignant head and neck tumors.
- Trial name
- NCT07040969
- Testing
- Spray of spirulina derivatives, Radiotherapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- West China Hospital
Radiation-induced Oral Mucositis
Traditional Chinese Medicine Oral Liquids and Mouthwashes for Radiation-induced Oral Mucositis in Head and Neck Cancer Patients
Evaluate the efficacy and safety of traditional Chinese medicine oral liquid and mouthwash in the treatment of radiotherapy induced oral mucositis in patients with head and neck malignancies
- Trial name
- NCT07282483
- Testing
- Qingying oral liquid and modified Da Huang-Huang Lian Xiexin mouthwash, radiotherapy
- Where
- China
- Volunteers
- 118 people
- Sponsor
- West China Hospital
Radiation-induced Oral Mucositis
Benzydamine for Radiation-Induced Oral Mucositis in Patients Receiving High-Dose Radiotherapy
This single-center, open-label, randomized clinical trial evaluates the effect of 0.15% benzydamine hydrochloride (Difflam) oral spray on the severity of radiation-induced oral mucositis in patients with head and neck cancer…
- Trial name
- NCT07467759
- Testing
- benzydamine hydrochloride, saline mouth rinse
- Where
- Syria
- Volunteers
- 35 people
- Sponsor
- Latakia University
Radiation Induced Oral Mucositis, Oral Mucositis
Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial
This triple-blinded, randomized controlled clinical trial investigates the effectiveness of L-arginine and L-glutamine oral suspensions in managing radiation-induced oral mucositis (RIOM) in patients with head and neck cancer…
- Conditions
- Radiation Induced Oral Mucositis, Oral Mucositis, Oral Mucositis Due to Radiation
- Trial name
- NCT07020754
- Testing
- L-arginine Oral Suspension, L-glutamine Oral Suspension, Maltodextrin Oral Suspension (Control)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Ain Shams University
Head and Neck Cancer (H&Amp;Amp;N), Radiation-induced Oral Mucositis
Mouthwash Temperature and Oral Mucositis in Head and Neck Radiotherapy
This single-center randomized controlled trial evaluates the effects of cold (15-20°C) versus room-temperature (30-35°C) water gargling on oral mucositis severity, pain, and comfort in patients with head and neck cancer…
- Conditions
- Head and Neck Cancer (H&Amp;Amp;N), Radiation-induced Oral Mucositis, Supportive Care, Nursing Interventions
- Trial name
- CoolRinseHNC (NCT07252557)
- Testing
- Water Rinse at Different Temperatures
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chung Shan Medical University
Radiation-Induced Oral Mucositis, Head &Amp; Neck Cancer
Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer
This study aims to find out if taking rice bran supplements can help reduce the painful mouth sores (oral mucositis) that often occur in patients with head and neck cancer who receive radiation therapy.
- Conditions
- Radiation-Induced Oral Mucositis, Head &Amp; Neck Cancer, Head &Amp; Neck Squamous Cell Carcinoma
- Trial name
- RICE-MUC (NCT07242859)
- Testing
- rice bran
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Christina Milad Lobos
Head and Neck Cancer, Radiation-Induced Mucositis
A Randomized Controlled Study on the Improvement of Medical Experience for Patients With Radiation-induced Oropharyngeal Mucositis Based on the RIS System of the Internet of Things
This study is a researcher-initiated, multi-center, prospective, two-arm interventional randomized controlled study across the country.
- Trial name
- NCT07126457
- Testing
- RIS system
- Where
- 4 sites in China
- Volunteers
- 110 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Head and Neck Cancer, Radiation-Induced Mucositis
Comparative Study of New Classification and Traditional Classification of Radioactive Oropharyngeal Mucositis
Radiation oropharyngeal mucositis is one of the most painful side effects of radiotherapy in patients with head and neck tumors.
- Trial name
- NCT06307327
- Where
- 4 sites in China
- Volunteers
- 264 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Radiation-induced Oral Mucositis
Hydroxychloroquine Sulfate Tablets for Radiation-induced Oral Mucositis
Evaluate the safety, tolerance and efficacy of hydroxychloroquine sulfate tablets the prevention and treatment of oral mucositis and dysgeusia in patients undergoing radiotherapy
- Trial name
- RIOM (NCT06939582)
- Testing
- Hydroxychloroquine Sulfate Tablets
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Xingchen Peng
Radiation Dermatitis, Radiation-induced Oral Mucositis
A Reminder App to Reduce Radiation Dermatitis Rates in Patients with Head-and-Neck Cancer
The goal of this randomized trial is to investigate whether the addition of a reminder app to standard care leads to a reduction of dermatitis and oral mucositis during radio(chemo)therapy for locally advanced squamous cell…
- Trial name
- RAREST-02 (NCT04110977)
- Testing
- mobile application (reminder app)
- Where
- 4 sites in Germany, Spain
- Volunteers
- 60 people
- Sponsor
- University Hospital Schleswig-Holstein
Radiation-Induced Mucositis
Effect of N-acetyl Cysteine and Zinc in Management of Head and Neck Cancer Radiotherapy Induced Oral Mucositis
The majority of individuals diagnosed with head and neck cancer, who undergo radiotherapy or concurrent Chemoradiotherapy, experience oral mucositis.
- Trial name
- NCT06482034
- Testing
- N-acetyl cysteine, Zinc sulfate, saline mouth wash
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Mucositis, Hematopoietic Stem Cell Transplantation
Effects of Mesenchymal Stem Cell Supernatant on Prevention and Treatment of Skin/Mucosal Injury in Hematology Patients
This clinical trial is studying the effects of mesenchymal stem cell (MSC) culture supernatant on the prevention and treatment of mucosal injuries in patients undergoing hematopoietic stem cell transplantation (HSCT).
- Conditions
- Mucositis, Hematopoietic Stem Cell Transplantation, Chemotherapy-Induced Mucositis, Radiation-Induced Mucositis
- Trial name
- MSC-MucInj (NCT06599346)
- Testing
- Standard Care, MSC Supernatant + Standard Care
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The General Hospital of Western Theater Command
Radiation Mucositis, Oral Mucositis (Ulcerative) Due to Radiation
Effectiveness of Topical Olive Oil in Prevention and Management of Radiation Induced Oral Mucositis
This research aims to investigate the effectiveness of topical olive oil application both clinically and biochemically as a suitable affordable treatment modality for prevention and management of radiation oral mucositis and its…
- Conditions
- Radiation Mucositis, Oral Mucositis (Ulcerative) Due to Radiation, Radiation-Induced Mucositis
- Trial name
- NCT05322421
- Testing
- Topical Olive Oil, Sodium bicarbonate 5% solution
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Salma Hesham Elhoufi