Clinical trials: Radiculopathies
Low Back Pain, Multifidus
Effects of Isolated Lumbar Extension Resistance Training Alone and in Combination with General Exercise and Manual Therapy
This study examines effects of machine-based isolated lumbar extension resistance exercise (ILEX) on paraspinal muscle morphology and function, as well as pain intensity, disability and quality of life in patients with chronic…
- Conditions
- Low Back Pain, Multifidus, Exercise Therapy, Diagnostic Imaging
- Trial name
- NCT06890052
- Testing
- Targeted exercise program, Targeted exercise as part of an integrative therapy program
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Radiculopathy Lumbar
Effectiveness of Stability Ball Training, Dead Bug Exercises, and Their Combination on Reducing Specific Low Back Pain
This study is a single-blinded, randomized controlled trial (RCT) focused on individuals aged 30 to 50 with acute specific low back pain (lumbar radiculopathy).
- Trial name
- NCT06749574
- Testing
- stability ball exercises, dead bug exercise, Combined Groupo
- Where
- Pakistan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Superior University
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lumbar Radiculopathy
Study of the Diagnostic Accuracy of the Neurodynamic Tests in Patients With Lumbar Radiculopathy
Lumbar radiculopathy is a relevant cause of disability and morbidity, accounting for between 23 and 57% of the cases of patients with low back pain and representing a significant expense due to the sick leave and health care that…
- Trial name
- NCT05636917
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Cervical Radiculopathy, Cervical Myelopathy
Quantitative Imaging of Cervical Spinal Structures - the DISC Pilot Study -
The aim of this study is to explore a multi-parametric quantitative MRI approach to measure cervical intervertebral discs, the spinal cord and its nerve roots in healthy participants and patients with cervical degenerative disc…
- Trial name
- DISC (NCT06610175)
- Testing
- Quantitative MRI and anatomical MRI
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Lumbar Radiculopathy
Effect of High Versus Low-level Laser Therapy in Patients of Lumber Radiculopathy
To Compare the effects of high-level laser therapy (HLLT) and low-level laser therapy (LLLT) on pain in patients with lumbar radiculopathy.
- Trial name
- NCT06240845
- Testing
- High-level laser therapy, Low-level laser therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Radiculopathy, Lumbosacral Region, Back Pain With Radiation
Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.
This will be a placebo controlled, randomized, double-blind, comparative effectiveness study, in which we patients are enrolled during an emergency department (ED) visit for acute radicular low back pain (LBP) and followed by…
- Conditions
- Radiculopathy, Lumbosacral Region, Back Pain With Radiation, Low Back Pain
- Trial name
- NCT05721027
- Testing
- Ibuprofen 400 mg, Dexamethasone Oral, Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Lumbar Radiculopathy, Central Sensitisation
Identifying Pain Generators and Potentiators of Residual Complaints Following Lumbar Discectomy
Lumbar discectomy (i.e. surgically removing a hernia) is frequently performed in Belgium to treat lumbar radiculopathy. Every year >12,000 interventions are performed with variable long-term results.
- Trial name
- DISC-PAIN (NCT05022251)
- Testing
- Lumbar discectomy
- Where
- Belgium
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cervical Radiculopathy
Effectiveness of Neck Isometric Exercises and Cervical Mobilization on Cervical Radiculopathy
Effectiveness of neck isometric exercises and cervical mobilization will be compared to observe the efficacy of these techniques on cervical radiculopathy
- Trial name
- NCT05884567
- Testing
- Isometric exercises, Mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Radiculopathy Lumbar
A Two-part Proof-of-Concept Study Assessing the Safety and Efficacy of LAT8881 in Lumbar Radicular Pain
The study consists of two parts. Part A will evaluate the safety and tolerability of intravenous LAT8881 in healthy volunteers using an ascending dose schedule.
- Trial name
- NCT05298306
- Testing
- LAT8881
- Where
- Australia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lateral Pharma Pty Ltd
Discopathy, Herniated Cervical Disc
Post Market Clinical Follow up Study With the Cervical Disc Prothesis MOVE®-C
Study design: International, prospective, multicentre, non-randomised, observational study according to § 23b MPG. Objectives: Observational study to confirm the safety and performance of the cervical disc prosthesis MOVE®-C.
- Conditions
- Discopathy, Herniated Cervical Disc, Stenoses, Spinal, Radiculopathy
- Trial name
- PMCF_MOVE®-C (NCT05035693)
- Testing
- MOVE®-C
- Where
- 7 sites in Austria, Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- NGMedical GmbH
Low Back Pain, Lumbosacral Radiculopathy
A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief
The purpose of this study is to collect information about how patients feel when doctors manage their pain after lumbar spine surgery using a combination of EXPAREL® and bupivacaine injected into the lumbar spine at the end of…
- Conditions
- Low Back Pain, Lumbosacral Radiculopathy, Lumbar Disc Degeneration, Lumbar Disc Herniation
- Trial name
- NCT03514277
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Cervical Radiculopathy
Sustained Natural Apophyseal Glides and Mechanical Cervical Traction in the Management of Cervical Radiculopathy
Sustained natural apophyseal glides (SNAGS), is a form of manual therapy, involved a combination of a sustained facet glide with active motion, followed by overpressure.
- Trial name
- SNAG&MCT (NCT03362567)
- Testing
- Sustained Natural Apophyseal Glides, Mechanical Cervical Traction
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University
Demyelinating Disorders, MCI
Exploring the Utility of [18F]3F4AP for Demyelination Imaging
The overall objective is to obtain an assessment of the pharmacokinetics of [18F]3F4AP in healthy volunteers and subjects with demyelinating diseases such as mild cognitive impairment (MCI), Alzheimer's Disease (AD), Multiple…
- Conditions
- Demyelinating Disorders, MCI, Alzheimer's Disease (AD), MS (Multiple Sclerosis)
- Trial name
- NCT06999434
- Testing
- [ 18F]3F4AP, [18F]MK6240, [11C]PIB
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Yale University
Lumbar Radiculopathy
Comparison Between the Imaging Consent Form and the Existing Narrative Consent Form
This is a single-center, randomized, double-blind clinical study to compare patient comprehension and anxiety by comparing a traditional paper consent form to a multimedia consent form for patients undergoing transforaminal…
- Trial name
- NCT05874427
- Testing
- Multimedia informed consent, Standard informed consent
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Radiculopathy Lumbar, MRI
Diffusion Tensor Sequences (DTI) for Study of Lumbar Roots by Magnetic Resonance Imaging (MRI)
Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots.
- Conditions
- Radiculopathy Lumbar, MRI, Diffusion Tensor Imaging
- Trial name
- OPTI-DTI (NCT04224077)
- Testing
- Optimisation of DTI sequences
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Lumbar Radiculopathy
Shacklock Neural Mobilization vs. McKenzie on Pain and Functional Disability in Lumbar Radiculopathy
This randomized comparative trial evaluates the efficacy of Shacklock neural mobilization versus the McKenzie extension principle in patients with lumbar radiculopathy.
- Trial name
- NCT07119697
- Testing
- Shacklock Neural Mobilization, McKenzie Extension Principle, Hydrocollator hot packs
- Where
- Saudi Arabia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- King Saud University
Neuropathic Pain, Radiculopathy, Cervical
Evaluation of Neuropathic Pain in the Context of Clinical Symptoms, Quantitative Sensory Tests and Imaging With FMRI
This study is planned to evaluate patients with upper extremity neuropathic pain due to cervical radiculopathy with clinical symptoms, Quantitative Sensory Testing(QST) and Functional Magnetic Resonance Imaging(fMRI).
- Trial name
- NCT03890315
- Testing
- Functional MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Cervical Radiculopathy
The Relationship Between Cervical Radiculopathy and Eye-hand Coordination
this study will be conducted to investigate if there is a relationship between cervical radiculopathy and eye-hand coordination.
- Trial name
- CR (NCT06169618)
- Testing
- cervical radiculopathy, normal group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University