Clinical trials: Radiocontrast Nephropathy
Coronary Atherosclerosis, Coronary Artery Disease
Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging
In a prospective international multicenter observational study, 1080 stable chest pain patients (REALITY Advanced registry of CCTA patients) with the suspected chronic coronary syndrome will be enrolled.
- Conditions
- Coronary Atherosclerosis, Coronary Artery Disease, Contrast-induced Nephropathy, Cerebrovascular Disease
- Trial name
- REALITY (NCT02440646)
- Testing
- Coronary computed tomography angiography, Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 4 sites in Estonia, Netherlands and 1 more
- Volunteers
- 1,080 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
Kidney Failure
PROMISS: Simvastatin Prevents the Contrast Induced Acute Renal Failure in Patients With Renal Insufficiency Undergoing Coronary Angiography
The contrast induced kidney toxicity has been known to affect the mortality and morbidity in the patients undergoing coronary angiography. But the mechanism and therapeutic strategy for it is not well known.
- Trial name
- NCT00259441
- Testing
- Simvastatin
- Where
- South Korea
- Volunteers
- 320 people
- Sponsor
- Seoul National University Hospital
Radiocontrast Nephropathy
N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients
Multiple agents have been studied to prevent radiocontrast nephropathy. One of these agents is N-Acetylcysteine. Previous trials to assess N-Acetylcysteine's efficacy in the prevention of contrast nephropathy have been promising.
- Trial name
- NCT00780962
- Testing
- N-Acetylcysteine (NAC), 0.9% Sodium-chloride
- Where
- United States
- Volunteers
- 399 people
- Sponsor
- Beth Israel Deaconess Medical Center
Radiocontrast-Induced Nephropathy, Chronic Kidney Disease
Efficacy of N-Acetylcysteine in Prevention of Post-Catheterization Contrast-Induced Nephropathy in Diabetic Patients With Chronic Kidney Disease
Contrast-induced nephropathy (CIN) is the third most common cause of hospital acquired acute kidney injury, accounting for 10% of all cases. The pathophysiology of CIN is unclear. Possible mechanisms involve 1.
- Conditions
- Radiocontrast-Induced Nephropathy, Chronic Kidney Disease, Diabetes Mellitus
- Trial name
- NCT00808795
- Testing
- N-acetylcysteine
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Tehran University of Medical Sciences
Acute Abdomen, Radiocontrast Nephropathy
Intravenous Contrast Computed Tomography Versus Native Computed Tomography in Patients With Acute Abdomen and Impaired Renal Function
Computer tomography (CT) is the primary imaging option for acute abdominal pain in adults. Intravenous (IV) contrast media is used to improve the CT quality.
- Trial name
- INCARO (NCT04196244)
- Testing
- Abdominal or body CT with intravenous contrast, Abdominal or body CT without intravenous contrast (native CT)
- Where
- 3 sites in Finland
- Volunteers
- 994 people
- Sponsor
- Helsinki University Central Hospital
Kidney Function Affection Upon Exposure to Radiocontrast, Diabetes
Contrast Nephropathy in Type 2 Diabetes
To study the effect of radiocontrast material on kidney functions in diabetics with microalbuminuria
- Conditions
- Kidney Function Affection Upon Exposure to Radiocontrast, Diabetes, Microalbuminuria
- Trial name
- VCG4 (NCT03470454)
- Testing
- Linagliptin Oral Tablet
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
Radiocontrast-induced Nephropathy
Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material
Millions of people receive radiographic contrast material for investigations like CT and coronary angiography. While considered safe in healthy patients, it can cause acute renal impairment.
- Trial name
- NCT00558142
- Testing
- Acetylcysteine, Visipaque 320
- Where
- United Kingdom
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Renal Failure, Kidney Failure
COOL RCN: Cooling to Prevent Radiocontrast Nephropathy
Radiographic contrast agents are administered to all patients undergoing diagnostic or interventional catheterization procedures.
- Conditions
- Renal Failure, Kidney Failure, Renal Insufficiency
- Trial name
- NCT00306306
- Testing
- Reprieve Endovascular Temperature Therapy System
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Radiant Medical
Contrast Induced Nephropathy
Erythropoietin in Radiocontrast Induced Nephropathy (ERIN) Trial
Full Title: A Randomized Controlled Trial of Procrit for the Prevention of Acute Renal Failure in Patients Receiving Intravenous Contrast Primary Objective: To evaluate the efficacy of a one-time dose of intravenous…
- Trial name
- ERIN (NCT00476619)
- Testing
- erythropoeitin
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Brigham and Women's Hospital
Acute Kidney Injury
Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent
This trial will evaluate whether treatment with CRMD001 (unique formulations of the iron chelator, Deferiprone) will reduce morbidity and mortality in subjects with Chronic Kidney Disease (CKD) and additional risk factors.
- Trial name
- NCT01391520
- Testing
- deferiprone
- Sponsor
- CorMedix Therapeutics