Clinical trials: Radiodermatitis
Breast Cancer, Breast Cancer Stage
A Study of Oleogel-S10 Gel for the Treatment of Radiation Dermatitis in People With Breast Cancer
The purpose of this study is find out whether Oleogel-S10 is an effective treatment for radiation dermatitis when it is used in combination with a standard wound treatment cream called triamcinolone.
- Conditions
- Breast Cancer, Breast Cancer Stage, Breast Cancer Stage I, Breast Cancer Stage II
- Trial name
- NCT05190770
- Testing
- Triamcinolone Acetonide, Oleogel-S10
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Head and Neck Cancer, Breast Cancer
Neoviderm Skin Emulsion in the Prevention of Radiation Dermatitis
The purpose of this study is to determine whether NeoVIDERM is effective at preventing radiation dermatitis in patients receiving external beam radiation therapy to the head and neck or breast areas.
- Trial name
- NCT01701466
- Testing
- Aveeno cream, Flamazine cream, NeoVIDERM cream
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Breast Cancer, Radiodermatitis
Artificial Intelligence Powered Digital Education Based on the Neuman Systems Model for Breast Cancer Patients Receiving Radiotherap
The purpose of this clinical trial is to evaluate the effect of an artificial intelligence-supported digital education program developed based on the Neuman Systems Model on radiodermatitis severity and quality of life in women…
- Trial name
- NCT07649902
- Testing
- Neuman-Based AI-Supported Digital Education Program, Standard Care (in control arm)
- Volunteers
- 38 people
- Sponsor
- Ataturk University
Radiation Dermatitis
Clinical Study to Evaluate Safety and Efficacy of KAM1403 Gel to Treat Radiation Dermatitis
The main purpose of this study is to demonstrate the safety and efficacy of KAM1403 GEL in reducing the symptoms of mild to moderate Radiation Dermatitis.
- Trial name
- kam1403 (NCT02051907)
- Testing
- KAM1403 Gel, aloevera gel
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Kamedis Ltd.
Radiodermatitis
Evaluation of Therapeutic Efficacy in Use of Chamomilla Gel, Chamomilla Infuse and Urea in Radiodermatitis
This study aims to evaluate therapeutics interventions in radiodermatitis in patients with breast or head and neck cancer. The data collect is going to begin after determining the better dose in a dose-response curve that is…
- Trial name
- ChamomillaTH (NCT02251392)
- Testing
- Chamomila recutita Gel, Chamomila recutita Infuse, Urea cream based
- Volunteers
- 100 people
- Sponsor
- University of Brasilia
Breast Carcinoma
Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy
This study evaluates patient-reported experiences of radiation dermatitis in patients with breast cancer undergoing radiotherapy.
- Trial name
- NCT06953245
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Acute Radiation Dermatitis, Traditional Chinese Medicine (TCM)
Efficacy and Safety of Qibei Jiedu Formula for Preventing and Managing Acute Radiation Dermatitis in Breast Cancer Patients
1. To evaluate the preventive and therapeutic effects of Qibei Jiedu Formula on acute radiation dermatitis in breast cancer patients, including the incidence of grade 2 or higher radiation dermatitis, wound healing time, and…
- Conditions
- Acute Radiation Dermatitis, Traditional Chinese Medicine (TCM), Breast Cancer
- Trial name
- NCT07380230
- Testing
- Standard Basic Treatment Combined with Qibei Jiedu Formula, Standard Basic Treatment Combined with Qibei Jiedu Formula simulator
- Where
- China
- Volunteers
- 60 people
- Sponsor
- LI FENG
Radiation Dermatitis Acute
Acute Radiation Dermatitis After Adjuvant Radiotherapy for Breast Cancer Patients With the Use of Silver-Plated Technology
Patients who are eligible to receive adjuvant whole breast radiotherapy with or without regional nodal irradiation as part of their care will be included in this study.
- Trial name
- NCT06831084
- Testing
- Silver plated technology (SPT) dressing
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Parul Barry
Radiodermatitis; Acute
A Study of GR1014 Cutaneous Gel for the Prevention of Skin Reactions Caused by Radiation Therapy for Breast Cancer
This clinical trial is testing a new skin gel called GR1014-CG to evaluate its safety and see if it can help prevent or reduce skin irritation (such as redness, soreness, etc.) caused by radiation therapy (RT) after…
- Trial name
- GuARD (NCT07192588)
- Testing
- GR1014-CG 2.4%, Vehicle Gel, Radiation Therapy
- Where
- 4 sites in France, United Kingdom
- Volunteers
- 273 people
- Sponsor
- Graegis Pharmaceuticals Ltd
Head and Neck Carcinoma, Radiation-Induced Dermatitis
Modified Dakin's Solution in Reducing Radiation-Induced Dermatitis in Patients With Head and Neck Cancer Undergoing Radiation Therapy
This randomized phase 3 trial studies how well modified Dakin's solution works in reducing radiation-induced dermatitis, a common skin reaction to radiation therapy, in patients with head and neck cancer undergoing radiation…
- Trial name
- NCT02369835
- Testing
- Dakin's solution
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- Stanford University
Head and Neck Neoplasms, Radiodermatitis
Topical Boswellia Serrata 2% to Prevent Radiation Dermatitis in Head and Neck Cancer
This study evaluates a topical 2% Boswellia serrata (Indian olibanum) gum-resin cream for the prevention of acute radiation-induced dermatitis in patients with head and neck cancer undergoing radiotherapy.
- Trial name
- NCT07778290
- Testing
- Boswellia serrata 2% topical cream
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Youssef Hashem Hafez
Radiodermatitis, Breast Neoplasms
Patient Reported Outcomes Using Mepitel Film During Radiotherapy
Breast cancer patients in post-operative radiotherapy (RT) often experience acute skin reactions like erythema, pain, itching and oversensitivity.
- Conditions
- Radiodermatitis, Breast Neoplasms, Side Effect
- Trial name
- NCT06133218
- Testing
- Mepitel Film
- Volunteers
- 101 people
- Sponsor
- Odense University Hospital
Mucositis Oral, Head and Neck Cancer
Photobiomodulation for the Prevention of Radiation Induced Oral Mucositis
Radiotherapy for head and neck cancer can cause severe mucositis (ulcers in the mouth) and pain. Photobiomodulation (Light therapy) will be used before and during radiotherapy to try to reduce the occurence and severity of…
- Conditions
- Mucositis Oral, Head and Neck Cancer, Radiation Dermatitis
- Trial name
- NCT04671862
- Testing
- Photobiomodulation
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Ottawa Hospital Research Institute
Radiation Dermatitis, Breast Cancer
Topical Dermaprazole for Radiation Dermatitis in Breast Cancer Patients (TOPAZ)
Radiotherapy is a mainstay of treatment in breast cancer treatment, in the adjuvant setting. Radiation dermatitis occurs in up to 65% of these patients; currently, there is no standard of care for this treatment-related toxicity.
- Trial name
- NCT05269160
- Testing
- Dermaprazole 1%, Dermaprazole 2%
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Baylor College of Medicine
Radiation Dermatitis
Efficacy of Superoxide Dismutase in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer .
Radiotherapy always results in many complications such as radiation dermatitis,dry mouth, cranial nerve damage, and swallowing function.
- Trial name
- NCT07399990
- Testing
- Saline Spray, SOD spray
- Volunteers
- healthy volunteers welcome
- Sponsor
- West China Hospital
Radiation-Induced Skin Injury
Akkermansia Muciniphila (AKK) for Radiation-Induced Skin Injury
This study is a multicenter, open-label, Phase I single-arm clinical trial evaluating the safety and tolerability of a topical AKK probiotic preparation (Akkermansia muciniphila) for the prevention and treatment of…
- Trial name
- AKK-RIS (NCT07635277)
- Testing
- AKK Topical Preparation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- West China Hospital
Radiation Dermatitis
Utilizing Topical Sodium Hypochlorite to Ameliorate Radiation Dermatitis
The objective of the pilot study is to determine compliance, acceptability, and feasibility of using topical sodium hypochlorite to ameliorate or reduce radiation dermatitis, and to collect preliminary data and estimates for…
- Trial name
- NCT04630821
- Testing
- Dilute Sodium Hypochlorite solution
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Northwestern University
Breast Cancer, Radiation Dermatitis
Hydrosorb® Versus Control in the Management of Radio-induced Skin Toxicity: Multicentre Controlled Phase III Randomized Trial
The primary objective consisted of avoiding deterioration and/or restoring the integrity of the skin of patients treated by radiotherapy, right from the first signs of grade 1 or 2 radiation dermatitis.
- Trial name
- HYDROSORB (NCT02839473)
- Testing
- Castalie water spray, Hydrogel Hydrosorb®
- Where
- 2 sites in France
- Volunteers
- 278 people
- Sponsor
- Institut Curie
Breast Carcinoma
Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy
This phase III trial studies how well Mepitel Film works in reducing radiation dermatitis (redness and peeling) in patients with breast cancer during radiation therapy after a mastectomy.
- Trial name
- NCT04989504
- Testing
- Best Practice, Wound Dressing Material, Quality-of-Life Assessment
- Where
- 49 sites in United States
- Volunteers
- 216 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Radiation Induced Oral Mucositis, Radiodermatitis
Taurine's Therapeutic Effect on Acute Radiation-induced Oral Mucositis and Dermatitis
This is a single-center, double-blind, randomized controlled study. The patients were divided into control group and experimental group, 80 cases each.
- Trial name
- NCT07029178
- Testing
- Taurine granule
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University