Clinical trials: Radiofrequency Ablation
Chronic Low-back Pain, Facet Joint Pain
Cryoneurolysis Outcome on Pain Experience (COPE) in Patients With Low-back Pain
This study will provide information on the effectiveness of cryoneurolysis for patients with facet joint pain syndrome, and help to establish whether cryoneurolysis should be implemented in clinical practice for this patient…
- Conditions
- Chronic Low-back Pain, Facet Joint Pain, Degeneration Lumbar Spine, Facet Joint Syndrome
- Trial name
- COPE (NCT04786145)
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hepatocellular Carcinoma
Comparison of Microwave and Radiofrequency Ablation for Liver
According to randomized controlled trial requirement, the therapeutic effectiveness of cooled-probe microwave ablation and radiofrequency ablation on early-stage hepatocellular carcinoma is compared to find a better approach for…
- Trial name
- NCT02539212
- Testing
- microwave ablation, radiofrequency ablation
- Where
- China
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Knee Osteoarthritis
Comparison of Conventional and Cooled Radiofrequency Ablation in Knee Osteoarthritis
The aim of this study was to examine and compare the effects of conventional and cooled radiofrequency ablation on pain and disability levels in patients with knee pain resistant to other treatments due to knee osteoarthritis.
- Trial name
- NCT06863181
- Testing
- Radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Small Renal Masses (SRM)
Stereotactic Body Radiation Therapy Versus Radiofrequency Ablation for Small Renal Masses
The execution of this study is pertinent to evaluating SBRT's short- and long-term efficacy and safety in the treatment of SRMs. This study will be the first to compare RFA and SBRT in the treatment of SRMs.
- Trial name
- SBRT vs RFA (NCT03811665)
- Testing
- Radiofrequency Ablation, Stereotactive body radiation therapy
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Type-2 Diabetes Mellitus
A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)
The purpose of this study is to assess the safety, tolerability and effectiveness of RF vapor ablation of the proximal intestinal mucosa.
- Trial name
- RESTORE-1 (NCT07355270)
- Testing
- RF Vapor Ablation
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Aqua Medical, Inc.
Premature Ventricular Contraction
Comparision of PVC Ablation Techniques
Several reports have shown the utility of PVC ablation with cryo catheters. The aim of this study is to compare the outcomes and safety of Cryo vs. RF for PVCs.
- Trial name
- PVC (NCT03086902)
- Testing
- Radiofrequency Ablation Catheter, Cryo Ablation catheter
- Volunteers
- 88 people
- Sponsor
- Sheba Medical Center
Radiofrequency Ablation
To Improve the Clinical Outcome of Ultrasound-guided Radiofrequency Ablation by NAVIRFA® Navigation System.
Ultrasonic-guided radiofrequency ablation is the most common minimally invasive treatment for liver cancer. This study will use my country's self-developed intelligent ultrasonic navigation tool (NAVIRFA® Navigation System) to…
- Trial name
- NCT05818176
- Testing
- NAVIRFA® Navigation System, ultrasound
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Esophageal Squamous Cell Neoplasia (ESCN)
RFA for Flat Type High-grade and Medium-grade Intraepithelial Squamous Neoplasia
Multicenter, prospective cohort clinical trial in greater China
- Trial name
- REACH (NCT02953418)
- Testing
- Radiofrequency ablation
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Medtronic - MITG
Thyroid Nodule, Thyroid Cancer
The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer
The goal of this clinical trial is to test radiofrequency ablation (RFA) in thyroid cancers ≤2 cm in diameter. The main question it aims to answer is: What is the feasibility of RFA use for low-risk thyroid cancers (≤2 cm)?…
- Trial name
- NCT06929650
- Testing
- Radiofrequency ablation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Heart Failure
NoYA RAISE Trial II (Radiofrequency Ablation-Based Interatrial Shunt for Heart Failure)
A Prospective, Multiple Center, and Objective Performance Criteria Study to Evaluate the NoYA™ Radiofrequency Interatrial Shunt System manufactured by NoYA Medtech (Hangzhou) Co., Ltd.
- Trial name
- NCT05375110
- Testing
- NoYA™ Radiofrequency Interatrial Shunt System
- Where
- 31 sites in China
- Volunteers
- 120 people
- Sponsor
- Hangzhou NOYA MedTech Co. Ltm.
Recovery
Comparison of Remimazolam With Flumazenil vs. Propofol During RFCA for Atrial Fibrillation
This prospective randomized trial aims to compare recovery time from discontinuation of remimazolam followed by flumazenil administration vs.
- Trial name
- NCT05397886
- Testing
- Remimazolam Besylate, Flumazenil, Propofol
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital
Atrial Fibrillation
Prospective Cohort Study of the Risk of Recurrent Atrial Fibrillation After Radiofrequency Ablation
In this study, the continuous inclusion of atrial fibrillation patients treated by catheter ablation in the Department of Cardiology, Peking University Third Hospital, through the collection of clinical data and outpatient…
- Trial name
- NCT05638841
- Testing
- After radiofrequency ablation of atrial fibrillation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Paroxysmal Atrial Fibrillation (PAF)
Clinical Evaluation of the Blazer Open-Irrigated Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillation
The purpose of this study is to establish the safety and effectiveness of the Blazer Open-Irrigated radiofrequency ablation catheter for the treatment of drug refractory, recurrent, symptomatic, paroxysmal atrial fibrillation.
- Trial name
- ZERO-AF (NCT01687166)
- Testing
- Blazer Open-Irrigated Ablation Catheter (Boston Scientific), FDA Approved Open-Irrigated Ablation Catheter
- Where
- 38 sites in United States, Australia and 7 more
- Volunteers
- 398 people
- Sponsor
- Boston Scientific Corporation
Chronic Low-back Pain
Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain
Low back pain (LBP) is the leading cause of disability worldwide. Currently available treatment options for treating low back facet joint pain include acupuncture, pain medications, psychotherapy, anti-inflammatory steroid…
- Trial name
- NCT06804551
- Testing
- iovera system, Radiofrequency ablation alone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Barrett's Esophagus, Radiofrequency Ablation
Radiofrequency Ablation in Patients With Barrett's Esophagus
The aim of this study is to establish a nationwide registry to collect data regarding the treatment of Barrett's Esophagus (BE) with radiofrequency ablation.
- Conditions
- Barrett's Esophagus, Radiofrequency Ablation, Gastroesophageal Reflux Disease
- Trial name
- RABE (NCT02793479)
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Matthias Paireder
Paroxysmal Atrial Fibrillation
Ectopy Triggering Ganglionated Plexus Ablation to Prevent Atrial Fibrillation
Atrial fibrillation (AF) is a common heart rhythm disorder which can significantly affect a patient's quality of life and cause strokes.
- Trial name
- GANGLIA-AF (NCT02487654)
- Testing
- Pulmonary vein isolation, Ganglionated plexus ablation
- Where
- 3 sites in United Kingdom
- Volunteers
- 116 people
- Sponsor
- Imperial College London
Osteoarthritis, Knee
Genicular Radiofrequency Ablation Following Total Knee Arthroplasty
Currently, nearly 1 million total knee arthroplasties (TKA) are performed yearly in the United States. Three million are projected to be performed in 2040.
- Trial name
- GRATKA (NCT05283889)
- Testing
- Genicular Radiofrequency Ablation
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of Calgary
Varicose Veins of Lower Limb, Varicose Veins
Compression And Functional Ability After Endovenous Varicose Vein Treatment
Study's aim is to study possible differences in post-operative rehabilitation, functional ability and visual disturbances after endovascular varicose intervention (RF-catheter and foam sclerotherapy) in two study groups, where…
- Trial name
- NCT03613376
- Testing
- Class II compression stockings
- Where
- Finland
- Volunteers
- 109 people
- Sponsor
- Oulu University Hospital
Atrial Fibrillation
Comparison of RF and crYoballoon ablatiOn Therapy of AF（CRYO-AF）
It's a multi-center, prospective, randomized, controlled clinical trial of cryoballoon versus radiofrequency ablation for paroxysmal atrial fibrillation.
- Trial name
- CRYO-AF (NCT03044951)
- Testing
- cryoballoon ablation, radiofrequency ablation
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Ruijin Hospital
Liver Tumor
Treat-and-resect Study of Echo Decorrelation Imaging-controlled Radiofrequency Ablation in Liver Tumors
This study will comprise the first pilot clinical trial of 3D, ultrasound-based thermal ablation control using echo decorrelation imaging, directly testing the capability of this approach to ensure reliable tumor treatment.
- Trial name
- NCT05211388
- Testing
- RFA controlled using echo decorrelation imaging, RFA controlled using standard manufacturer-specified algorithms
- Where
- United States
- Sponsor
- University of Cincinnati